Výsledky vyhledávání - "Valentina Sukonina"

FOXK1 and FOXK2 regulate aerobic glycolysis

Publikováno v: Nature. 566(7743)

Adaptation to the environment and extraction of energy are essential for survival. Some species have found niches and specialized in using a particular source of energy, whereas others-including humans and several other mammals-have developed a high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::92aa91e6a765b008524038c15117cb64
https://pubmed.ncbi.nlm.nih.gov/30700909

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Effects of hyperinsulinemia on lipoprotein lipase, angiopoietin-like protein 4, and glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 in subjects with and without type 2 diabetes mellitus

Autor: Toralph Ruge, Jan W. Eriksson, Elena Makoveichuk, Olessia Kroupa, Magdalena Lundgren, Maria Svensson, Gunilla Olivecrona, Valentina Sukonina

Publikováno v: Metabolism. 61:652-660

Our aims were to compare the systemic effects of insulin on lipoprotein lipase (LPL) in tissues from subjects with different degrees of insulin sensitivity. The effects of insulin on LPL during a 4-hour hyperinsulinemic, euglycemic clamp were studied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd6c3026231f7aecf7ff1bd7c2a82f1
https://doi.org/10.1016/j.metabol.2011.09.014

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Two primate-specific small non-protein-coding RNAs in transgenic mice: neuronal expression, subcellular localization and binding partners

Autor: Boris V. Skryabin, Valentina Sukonina, Marsha Bundman, Sergej Handel, Jürgen Brosius, Chenna R. Galiveti, Timofey S. Rozhdestvensky, Tasneem Khanam, Ursula Jordan

Publikováno v: Nucleic Acids Research

In a rare occasion a single chromosomal locus was targeted twice by independent Alu-related retroposon insertions, and in both cases supported neuronal expression of the respective inserted genes encoding small non-protein coding RNAs (npcRNAs): BC20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53d0b2e6e291a7a8a44dbff8806c539
https://doi.org/10.1093/nar/gkl1082

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Lipoprotein lipase in the kidney: activity varies widely among animal species

Autor: Knut Nordstoga, Thomas Olivecrona, Toralph Ruge, Barbara Frankel, Lucyna Neuger, Jitendra Gupta, Gunilla Olivecrona, Gengshu Wu, Stefan Barath, Bjørn O. Christophersen, Valentina Sukonina

Publikováno v: American Journal of Physiology-Renal Physiology. 287:F1131-F1139

Much evidence points to a relationship among kidney disease, lipoprotein metabolism, and the enzyme lipoprotein lipase (LPL), but there is little information on LPL in the kidney. The range of LPL activity in the kidney in five species differed by >5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676e6149948c1d97f309383627820db7
https://doi.org/10.1152/ajprenal.00089.2004

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Neuronal Untranslated BC1 RNA: Targeted Gene Elimination in Mice

Autor: Jürgen Brosius, Boris V. Skryabin, Ursula Jordan, Henri Tiedge, Valentina Sukonina, Lars Lewejohann, Ilham A. Muslimov, Norbert Sachser

Publikováno v: Molecular and Cellular Biology. 23:6435-6441

Despite the potentially important roles of untranslated RNAs in cellular form or function, genes encoding such RNAs have until now received surprisingly little attention. One such gene encodes BC1 RNA, a small non-mRNA that is delivered to dendritic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1c6f1934a06cb46bb9cf032c2c0f3d
https://doi.org/10.1128/mcb.23.18.6435-6441.2003

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Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue

Autor: Olessia Kroupa, Sander Kersten, Stefan K. Nilsson, Gunilla Olivecrona, Thomas Olivecrona, Frits Mattijssen, Rinke Stienstra, Evelina Vorrsjö, Valentina Sukonina

Publikováno v: BMC Physiology
BMC Physiology, Vol 12, Iss 1, p 13 (2012)
BMC Physiology 12 (2012)
BMC Physiology, 12

Background Lipoprotein lipase (LPL) hydrolyzes triglycerides in lipoproteins and makes fatty acids available for tissue metabolism. The activity of the enzyme is modulated in a tissue specific manner by interaction with other proteins. We have studie

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https://doi.org/10.1186/1472-6793-12-13

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Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed

Autor: Ewa Ehrenborg, Elena Makoveichuk, Gunilla Olivecrona, Petra Thulin, Valentina Sukonina, Olessia Kroupa, Thomas Olivecrona

Publikováno v: Biochemical and biophysical research communications. 425(2)

Lipoprotein lipase (LPL) hydrolyzes triglycerides in plasma lipoproteins causing release of fatty acids for metabolic purposes in muscles and adipose tissue. LPL in macrophages in the artery wall may, however, promote foam cell formation and atherosc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79bcdbfc694320c3915bdfabb299ba4
https://pubmed.ncbi.nlm.nih.gov/22820186

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The adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial function

Autor: Martin E. Lidell, Paula Itkonen, Zahra Arani, Fredrik Westberg, Tommy Nilsson, Xiao-Rong Peng, Julia Fernandez-Rodriguez, Sven Enerbäck, Markku Laakso, Valentina Sukonina, Erin L. Seifert, Adrienne Gowing, Rickard Westergren, Mary-Ellen Harper, Mikael Heglind, Simonetta Wallin

Publikováno v: Diabetes

OBJECTIVE Previous findings demonstrate that enhanced expression of the forkhead transcription factor Foxc2 in adipose tissue leads to a lean and insulin-sensitive phenotype. These findings prompted us to further investigate the role of Foxc2 in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd3d7c79eff67792dae428ac03da14d
https://pubmed.ncbi.nlm.nih.gov/21270254

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Acute hyperinsulinemia raises plasma interleukin-6 in both nondiabetic and type 2 diabetes mellitus subjects, and this effect is inversely associated with body mass index

Autor: J. Andrew Lockton, Valentina Sukonina, Toralph Ruge, Maria Svensson, Frida Renström, Theodore Lystig, Jan W. Eriksson

Publikováno v: Metabolism: clinical and experimental. 58(6)

Hyperinsulinemia is a characteristic of type 2 diabetes mellitus (T2DM) and is believed to play a role in the low-grade inflammation seen in T2DM. The main aim was to study the effect of hyperinsulinemia on adipokines in individuals with different le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4734b585a461db942f6edf62927391a
https://pubmed.ncbi.nlm.nih.gov/19375766

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