Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Valentina Siino"'
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33057- (2024)
Biochemical differences between sexes can also be seen in non-sexual organs and may affect organ functions and susceptibility to diseases. It has been shown that there are sex-biased visual perceptions and impairments. Abundance differences of eye pr
Externí odkaz:
https://doaj.org/article/0b19ace5403b4af898cdba731e3e0f75
Autor:
Kinjal Shah, Ahmad Nasimian, Mehreen Ahmed, Lina Al Ashiri, Linn Denison, Wondossen Sime, Katerina Bendak, Iryna Kolosenko, Valentina Siino, Fredrik Levander, Caroline Palm-Apergi, Ramin Massoumi, Richard B. Lock, Julhash U. Kazi
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The deregulation of BCL2 family proteins plays a crucial role in leukemia development. Therefore, pharmacological inhibition of this family of proteins is becoming a prevalent treatment method. However, due to the emergence of primary and ac
Externí odkaz:
https://doaj.org/article/ab4571946cdc4a52b01f17d2beb37ca1
Autor:
Muhammad Zubair Ashraf, Kanakachari Mogilicherla, Gothandapani Sellamuthu, Valentina Siino, Fredrik Levander, Amit Roy
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
The bark beetle, Ips typographus (L.), is a major pest of Norway spruce, Picea abies (L.), causing enormous economic losses globally. The adult stage of the I. typographus has a complex life cycle (callow and sclerotized); the callow beetles feed fer
Externí odkaz:
https://doaj.org/article/ce03b7a970174390bbb9b7fc8122d154
Autor:
Renato Ivan de Ávila, Sofía Carreira Santos, Valentina Siino, Fredrik Levander, Malin Lindstedt, Kathrin S. Zeller
Publikováno v:
Data in Brief, Vol 46, Iss , Pp 108878- (2023)
Dendritic cells are the sentinels of the immune system, linking the innate and adaptive immune response. Myeloid and dendritic cell models have been successfully used in in vitro approaches to predict adverse outcomes such as skin sensitization. We h
Externí odkaz:
https://doaj.org/article/1455b82e36e148ccb6c1771128b8b128
Autor:
Renato Ivan de Ávila, Sofía Carreira Santos, Valentina Siino, Fredrik Levander, Malin Lindstedt, Kathrin S. Zeller
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 2030-2041 (2022)
New approaches based on -omics technologies can identify biomarkers and processes regulated in response to xenobiotics, and thus support toxicological risk assessments. This is vital to meet the challenges associated with “cocktail effects”, i.e.
Externí odkaz:
https://doaj.org/article/8896b5f1c55e490f83f1f0c2cd7536ba
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Background Visual exploration of gene product behavior across multiple omic datasets can pinpoint technical limitations in data and reveal biological trends. Still, such exploration is challenging as there is a need for visualizations that a
Externí odkaz:
https://doaj.org/article/8d196063a86046959dfca0a6a194a96c
Autor:
Erna Davydova, Tadahiro Shimazu, Maren Kirstin Schuhmacher, Magnus E. Jakobsson, Hanneke L. D. M. Willemen, Tongri Liu, Anders Moen, Angela Y. Y. Ho, Jędrzej Małecki, Lisa Schroer, Rita Pinto, Takehiro Suzuki, Ida A. Grønsberg, Yoshihiro Sohtome, Mai Akakabe, Sara Weirich, Masaki Kikuchi, Jesper V. Olsen, Naoshi Dohmae, Takashi Umehara, Mikiko Sodeoka, Valentina Siino, Michael A. McDonough, Niels Eijkelkamp, Christopher J. Schofield, Albert Jeltsch, Yoichi Shinkai, Pål Ø. Falnes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Only very few enzymes are known to catalyze protein histidine methylation. Here, the authors show that METTL9 is responsible for most 1-methylhistidine modifications in mouse and human proteomes, and characterize METTL9′s substrate specificity and
Externí odkaz:
https://doaj.org/article/f285ea6c5c6e4717b078c180ed9b6cd5
Autor:
Sergio Mosquim Junior, Valentina Siino, Lisa Rydén, Johan Vallon-Christersson, Fredrik Levander
Publikováno v:
Cancers, Vol 14, Iss 23, p 5761 (2022)
In recent years, several advances have been achieved in breast cancer (BC) classification and treatment. However, overdiagnosis, overtreatment, and recurrent disease are still significant causes of complication and death. Here, we present the develop
Externí odkaz:
https://doaj.org/article/883ec0bf49bc453983a533bf7758daf0
Autor:
Valentina Siino, Pia Jensen, Peter James, Sonya Vasto, Antonella Amato, Flavia Mulè, Giulia Accardi, Martin Røssel Larsen
Publikováno v:
Nutrition and Metabolic Insights, Vol 14 (2021)
Obesity constitutes a major global health threat and is associated with a variety of diseases ranging from metabolic and cardiovascular disease, cancer to neurodegeneration. The hallmarks of neurodegeneration include oxidative stress, proteasome impa
Externí odkaz:
https://doaj.org/article/0e67a1893d5940d496e7cc6bc3bddb6e
Autor:
Patrizia Cancemi, Anna Aiello, Giulia Accardi, Rosalia Caldarella, Giuseppina Candore, Calogero Caruso, Marcello Ciaccio, Laura Cristaldi, Francesca Di Gaudio, Valentina Siino, Sonya Vasto
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Extracellular matrix metalloproteinases (MMPs) are a group of proteins that activate substrates by enzymatic cleavage and, on the basis of their activities, have been demonstrated to play a role in ageing. Thus, in order to gain insight into the path
Externí odkaz:
https://doaj.org/article/61c5c1e630b84c5492f8f0d14309bacb