Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Valentina Salsi"'
Autor:
Cinzia Bettio, Federico Banchelli, Valentina Salsi, Roberto Vicini, Oscar Crisafulli, Lucia Ruggiero, Giulia Ricci, Elisabetta Bucci, Corrado Angelini, Angela Berardinelli, Silvia Bonanno, Maria Grazia D’Angelo, Antonio Di Muzio, Massimiliano Filosto, Erica Frezza, Lorenzo Maggi, Tiziana Mongini, Elena Pegoraro, Carmelo Rodolico, Marina Scarlato, Gaetano Vattemi, Daniele Velardo, Giuliano Tomelleri, Roberto D’Amico, Giuseppe D’Antona, Rossella Tupler
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background In facioscapulohumeral muscular dystrophy (FSHD), it is not known whether physical activity (PA) practiced at young age is associated with the clinical presentation of disease. To assess this issue, we performed a retrospective co
Externí odkaz:
https://doaj.org/article/61de057bf13d4fb78dcd7f9489634400
Autor:
Cinzia Bettio, Valentina Salsi, Mirko Orsini, Enrico Calanchi, Luca Magnotta, Luca Gagliardelli, June Kinoshita, Sonia Bergamaschi, Rossella Tupler
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-13 (2021)
Abstract Background The Italian Clinical network for FSHD (ICNF) has established the Italian National Registry for FSHD (INRF), collecting data from patients affected by Facioscapulohumeral dystrophy (FSHD) and their relatives. The INRF has gathered
Externí odkaz:
https://doaj.org/article/f2cc7c6cc1104d04a0dd2afdd0dacf6e
Autor:
Ana Nikolic, Takako I Jones, Monica Govi, Fabiano Mele, Louise Maranda, Francesco Sera, Giulia Ricci, Lucia Ruggiero, Liliana Vercelli, Simona Portaro, Luisa Villa, Chiara Fiorillo, Lorenzo Maggi, Lucio Santoro, Giovanni Antonini, Massimiliano Filosto, Maurizio Moggio, Corrado Angelini, Elena Pegoraro, Angela Berardinelli, Maria Antonetta Maioli, Grazia D’Angelo, Antonino Di Muzio, Gabriele Siciliano, Giuliano Tomelleri, Maurizio D’Esposito, Floriana Della Ragione, Arianna Brancaccio, Rachele Piras, Carmelo Rodolico, Tiziana Mongini, Frederique Magdinier, Valentina Salsi, Peter L. Jones, Rossella Tupler
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2635 (2020)
Facioscapulohumeral muscular dystrophy (FSHD) is characterized by incomplete penetrance and intra-familial clinical variability. The disease has been associated with the genetic and epigenetic features of the D4Z4 repetitive elements at 4q35. Recentl
Externí odkaz:
https://doaj.org/article/5b6b3f45c2674a0395380962e0671831
Autor:
Vincenzo Zappavigna, Cristina Mecucci, Francesca Chiavolelli, Sebastian Fantini, Paolo Gorello, Silvia Ferrari, Valentina Salsi
PDF - K, Supplementary Figure 5. Interference of NUP98-fusions with APC/C activity involves primarily CDC20. HEK293 cells were transfected with a control siRNA or with siRNAs against the indicated proteins (CDC20 or CDH1), together with the expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7935e83dd2803c9a0628ae08d0850a
https://doi.org/10.1158/0008-5472.22402239.v1
https://doi.org/10.1158/0008-5472.22402239.v1
Autor:
Vincenzo Zappavigna, Cristina Mecucci, Francesca Chiavolelli, Sebastian Fantini, Paolo Gorello, Silvia Ferrari, Valentina Salsi
PDF - 2287K, Supplementary Figure 3. Mitotic index in transfected and in nocodazole arrested HEK293 cells. A, Mitotic index of control untransfected, nocodazole-arrested HEK293 and U937 cells. Cells were labelled with a specific anti-phosphoSer10 ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9540a238778b8a3e63d83b24cc576e7d
https://doi.org/10.1158/0008-5472.22402245.v1
https://doi.org/10.1158/0008-5472.22402245.v1
Autor:
Vincenzo Zappavigna, Cristina Mecucci, Francesca Chiavolelli, Sebastian Fantini, Paolo Gorello, Silvia Ferrari, Valentina Salsi
PDF - 1659K, Supplementary Figure 4. siRNA knock-down experiments. A, Immunoblots showing the effects of siRNAs on CDC20 or CDH1 protein expression. Anti-betaactin was used as a loading control. Graphs representing immunoblot quantitations are shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e504dc5c49f82602ffab5f950fb2944
https://doi.org/10.1158/0008-5472.22402242
https://doi.org/10.1158/0008-5472.22402242
Autor:
Vincenzo Zappavigna, Cristina Mecucci, Francesca Chiavolelli, Sebastian Fantini, Paolo Gorello, Silvia Ferrari, Valentina Salsi
PDF - 77K, Legends to Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e096eab59276db81f07f97984167a4a9
https://doi.org/10.1158/0008-5472.22402236.v1
https://doi.org/10.1158/0008-5472.22402236.v1
Autor:
Vincenzo Zappavigna, Cristina Mecucci, Francesca Chiavolelli, Sebastian Fantini, Paolo Gorello, Silvia Ferrari, Valentina Salsi
PDF - 2289K, Supplemental Figure 1. Expression of NUP98 and of NUP98 fusion oncoproteins in HEK293 cells. A, Schematic representation of the structures of human NUP98 (AAC50366) and of its chimeric oncoproteins. The GLFG repeats and the Rae1-interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61011a1d82b380de03897448c3183a54
https://doi.org/10.1158/0008-5472.22402251.v1
https://doi.org/10.1158/0008-5472.22402251.v1
Autor:
Vincenzo Zappavigna, Cristina Mecucci, Francesca Chiavolelli, Sebastian Fantini, Paolo Gorello, Silvia Ferrari, Valentina Salsi
PDF - 1450K, Supplementary Figure 2. Proteasome inhibition rescues NUP98-fusions effects on Securin and Cyclin B degradation. Western blot analysis showing securin (SEC) and cyclin B (CCNB1) levels in HEK293 cells transfected with the indicated const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa1ec99a93d05b2dedd14dcddd7073f
https://doi.org/10.1158/0008-5472.22402248
https://doi.org/10.1158/0008-5472.22402248
Data from NUP98 Fusion Oncoproteins Promote Aneuploidy by Attenuating the Mitotic Spindle Checkpoint
Autor:
Vincenzo Zappavigna, Cristina Mecucci, Francesca Chiavolelli, Sebastian Fantini, Paolo Gorello, Silvia Ferrari, Valentina Salsi
NUP98 is a recurrent fusion partner in chromosome translocations that cause acute myelogenous leukemia. NUP98, a nucleoporin, and its interaction partner Rae1, have been implicated in the control of chromosome segregation, but their mechanistic contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f09533a82985429d24abc14c484b44c
https://doi.org/10.1158/0008-5472.c.6506019
https://doi.org/10.1158/0008-5472.c.6506019