Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Valentina Pita-Grisanti"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Siderophores are iron chelating molecules produced by nearly all organisms, most notably by bacteria, to efficiently sequester the limited iron that is available in the environment. Siderophores are an essential component of mammalian iron homeostasi
Externí odkaz:
https://doaj.org/article/23a3027d65674b278cdf643ce9cb2b81
Altered Plasma Fatty Acid Abundance Is Associated with Cachexia in Treatment-Naïve Pancreatic Cancer
Autor:
Kristyn Gumpper-Fedus, Phil A. Hart, Martha A. Belury, Olivia Crowe, Rachel M. Cole, Valentina Pita Grisanti, Niharika Badi, Sophia Liva, Alice Hinton, Christopher Coss, Mitchell L. Ramsey, Anne Noonan, Darwin L. Conwell, Zobeida Cruz-Monserrate
Publikováno v:
Cells, Vol 11, Iss 5, p 910 (2022)
Cachexia occurs in up to 80% of pancreatic ductal adenocarcinoma (PDAC) patients and is characterized by unintentional weight loss and tissue wasting. To understand the metabolic changes that occur in PDAC-associated cachexia, we compared the abundan
Externí odkaz:
https://doaj.org/article/3a605ce68b1f40bc87416471aeadcd69
Autor:
Zobeida Cruz-Monserrate, Keri Schadler, Valentina Pita-Grisanti, Kristyn Gumpper-Fedus, Ali Lahooti, Hsiang-Yin Hsueh, Myrriah Chavez-Tomar
Publikováno v:
Pancreatology
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer, and the increasing incidence of PDAC may be related to the prevalence of obesity. Physical activity (PA), a method known to mitigate obesity by increasing total energy e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0dfb0727c6ec1d989e0b56ce343e42
https://doi.org/10.1016/j.pan.2021.10.004
https://doi.org/10.1016/j.pan.2021.10.004
Autor:
Kristyn Gumpper-Fedus, Olivia Crowe, Phil A. Hart, Valentina Pita-Grisanti, Ericka Velez-Bonet, Martha A. Belury, Mitchell Ramsey, Rachel M Cole, Niharika Badi, Stacey Culp, Alice Hinton, Luis Lara, Somashekar G. Krishna, Darwin L. Conwell, Zobeida Cruz-Monserrate
Publikováno v:
bioRxiv
ObjectivesChronic pancreatitis (CP) is an inflammatory disease that affects the absorption of nutrients like fats. Molecular signaling in pancreatic cells can be influenced by fatty acids (FAs) and changes in FA abundance could impact CP-associated c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d8193387ebe491e1e6397a3863a517
https://europepmc.org/articles/PMC9881940/
https://europepmc.org/articles/PMC9881940/
Autor:
Valentina Pita-Grisanti, Kelly Dubay, Ali Lahooti, Niharika Badi, Olivia Ueltschi, Kristyn Gumpper-Fedus, Hsiang-Yin Hsueh, Ila Lahooti, Myrriah Chavez-Tomar, Samantha Terhorst, Sue E. Knoblaugh, Lei Cao, Wei Huang, Christopher C. Coss, Thomas A. Mace, Fouad Choueiry, Alice Hinton, Jennifer M Mitchell, Rosemarie Schmandt, Michaela Onstad Grinsfelder, Karen Basen-Engquist, Zobeida Cruz-Monserrate
BACKGROUND & AIMSObesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), a deadly disease with limited preventive strategies. Lifestyle interventions to decrease obesity might prevent obesity-associated PDAC. Here, we examined whether d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82ed8042beb2fad95158dbe777544c7
https://doi.org/10.1101/2023.01.03.521203
https://doi.org/10.1101/2023.01.03.521203
Autor:
Valentina Pita Grisanti, Andrew W. Dangel, Maciej Pietrzak, Amy Hite, Zobeida Cruz-Monserrate
Publikováno v:
Cancer Research. 82:B008-B008
Background: Pancreatic Ductal Adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the US. Lipocalin 2 (LCN2) is upregulated in PDAC patients and promotes inflammation and tumor growth. LCN2 regulates iron levels, which are dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ea42c1f6e2181f61cbee6408cb61856
https://doi.org/10.1158/1538-7445.panca22-b008
https://doi.org/10.1158/1538-7445.panca22-b008
Autor:
Maciej Pietrzak, Andrea Ludwig, Madelyn Traczek, Zobeida Cruz-Monserrate, Rosa F. Hwang, Amy Webb, Olivia Ueltschi, Xiaokui Mo, Valentina Pita-Grisanti, Niharika Badi, Kristyn Gumpper, Andrew W. Dangel
Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease with poor outcomes. Iron is known to signal cellular responses, and its levels are regulated by lipocalin-2 (LCN2) expression, a PDAC pro-tumorigenic molecule. However, how iron a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f08d9e0148b8ae5cee35046fd103b70
Autor:
Samantha Terhorst, Niharika Badi, Jennifer M. Mitchell, Karen Basen-Engquist, Alice Hinton, Kelly Dubay, Myrriah Chavez-Tomar, Thomas A. Mace, Valentina Pita-Grisanti, Fouad Choueiry, Zobeida Cruz-Monserrate, Ali Lahooti, Olivia Ueltschi, Christopher C. Coss, Sue E. Knoblaugh
Publikováno v:
Cancer Research. 80:PO-034
Background: Obesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), a deadly disease with no preventive strategies. Lifestyle interventions to decrease obesity might serve to prevent obesity-induced PDAC. We examined whether decreasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e2559f4a74dd53bd3f83f4c5b83151b
https://doi.org/10.1158/1538-7445.panca20-po-034
https://doi.org/10.1158/1538-7445.panca20-po-034
Autor:
Pablo E. Vivas-Mejia, Valentina Pita-Grisanti, Ginette S Santiago-Sánchez, Kristyn Gumpper, Zobeida Cruz-Monserrate, Blanca I Quiñones-Díaz
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4365, p 4365 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 4365, p 4365 (2020)
Lipocalin-2 (LCN2) is a secreted glycoprotein linked to several physiological roles, including transporting hydrophobic ligands across cell membranes, modulating immune responses, maintaining iron homeostasis, and promoting epithelial cell differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6923a3e16093c7091207ec4f72a4b54
https://doi.org/10.3390/ijms21124365
https://doi.org/10.3390/ijms21124365
Publikováno v:
Journal of the Endocrine Society; 2024 Supplement, Vol. 8, pA1-A1192, 3359p