Validation of the Performance of A1HPV6, a Triage Blood Test for the Early Diagnosis and Prognosis of SARS-CoV-2 Infection

Autor: Pauline Maisonnasse, Thierry Poynard, Mehdi Sakka, Sepideh Akhavan, Romain Marlin, Valentina Peta, Olivier Deckmyn, Nesrine Braham Ghedira, Yen Ngo, Marika Rudler, Sylvie van der Werf, Stephane Marot, Dominique Thabut, Harry Sokol, Chantal Housset, Alain Combes, Roger Le Grand, Patrice Cacoub

Publikováno v: Gastro Hep Advances, Vol 1, Iss 3, Pp 393-402 (2022)

Background and Aims: Apolipoprotein A1 (A1) and haptoglobin (HP) serum levels are associated with the spread and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We have constructed and validated a multivariable ris

Externí odkaz: https://doaj.org/article/d512ccbd6fe74ee2be66d77c0226a4b7

External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV

Autor: Thierry Poynard, Jean Marc Lacombe, Olivier Deckmyn, Valentina Peta, Sepideh Akhavan, Victor de Ledinghen, Fabien Zoulim, Didier Samuel, Philippe Mathurin, Vlad Ratziu, Dominique Thabut, Chantal Housset, Hélène Fontaine, Stanislas Pol, Fabrice Carrat

Publikováno v: JHEP Reports, Vol 3, Iss 4, Pp 100298- (2021)

Background & Aims: The Liver Cancer Risk test algorithm (LCR1-LCR2) is a multianalyte blood test combining proteins involved in liver cell repair (apolipoprotein-A1 and haptoglobin), known hepatocellular carcinoma (HCC) risk factors (sex, age, and ga

Externí odkaz: https://doaj.org/article/2a6493e2f7954175b1cb400a894224aa

Performance of serum apolipoprotein-A1 as a sentinel of Covid-19.

Autor: Thierry Poynard, Olivier Deckmyn, Marika Rudler, Valentina Peta, Yen Ngo, Mathieu Vautier, Sepideh Akhavan, Vincent Calvez, Clemence Franc, Jean Marie Castille, Fabienne Drane, Mehdi Sakka, Dominique Bonnefont-Rousselot, Jean Marc Lacorte, David Saadoun, Yves Allenbach, Olivier Benveniste, Frederique Gandjbakhch, Julien Mayaux, Olivier Lucidarme, Bruno Fautrel, Vlad Ratziu, Chantal Housset, Dominique Thabut, Patrice Cacoub

Publikováno v: PLoS ONE, Vol 15, Iss 11, p e0242306 (2020)

BackgroundSince 1920, a decrease in serum cholesterol has been identified as a marker of severe pneumonia. We have assessed the performance of serum apolipoprotein-A1, the main transporter of HDL-cholesterol, to identify the early spread of coronavir

Externí odkaz: https://doaj.org/article/7670e55a12e8446e9f2a9702b4c12247

Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.

Autor: Valentina Peta, Chantal Tse, Hugo Perazzo, Mona Munteanu, Yen Ngo, An Ngo, Nittia Ramanujam, Lea Verglas, Maxime Mallet, Vlad Ratziu, Dominique Thabut, Marika Rudler, Vincent Thibault, Ina Schuppe-Koistinen, Dominique Bonnefont-Rousselot, Bernard Hainque, Françoise Imbert-Bismut, Michael Merz, Gerd Kullak-Ublick, Raul Andrade, Florian van Boemmel, Eckart Schott, Thierry Poynard, Drug Induced Liver Injury- Groupe Hospitalier Pitié-Salpêtrière, Drug Induced Liver Group of the Injury Safer and Faster Evidence-based Translation consortium

Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189436 (2017)

There is a clear need for better biomarkers of drug-induced-liver-injury (DILI).We aimed to evaluate the possible prognostic value of ActiTest and FibroTest proteins apoliprotein-A1, haptoglobin and alpha-2-macroglobulin, in patients with DILI.We ana

Externí odkaz: https://doaj.org/article/0fbb698e110c4d4ca92f5f00fed29596

Prospective external validation of a new non‐invasive test for the diagnosis of non‐alcoholic steatohepatitis in patients with type 2 diabetes

Autor: Stanislas Pol, Christian Boitard, Nathalie Gault, Jimmy Mullaert, Pauline Manchon, J.M. Castille, Sébastien Czernichow, Thierry Poynard, Jean-François Gautier, Béatrice Parfait, Benoit Terris, Estelle Marcault, Anaïs Vallet-Pichard, Etienne Larger, Valérie Paradis, Cédric Laouénan, F. Drane, Laurent Castera, Valentina Peta, Dominique Valla, Angelique Brzustowski, Olivier Deckmyn, Pierre Bedossa, Nassima Si Mohammed, Mark Ibberson, Dominique Roulot

Publikováno v: Alimentary Pharmacology & Therapeutics (Suppl)
Alimentary Pharmacology & Therapeutics (Suppl), 2021, 54 (7), pp.952-966. ⟨10.1111/apt.16543⟩
Alimentary Pharmacology & Therapeutics

Summary Background One of the unmet needs in patients with type 2 diabetes mellitus (T2DM) is the prediction of non‐alcoholic liver disease by non‐invasive blood tests, for each of the three main histological features, fibrosis, non‐alcoholic s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4521b5ffdae4c677d7c9f448add607b4
https://hal.sorbonne-universite.fr/hal-03350034