Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Valentina Perotti"'
Autor:
Andrea Anichini, Roberta Mortarini, Alessandro M. Gianni, Carmelo Carlo-Stella, Soldano Ferrone, Michele Milella, Nadia Zaffaroni, Marzia Pennati, Valentina Perotti, Ilaria Bersani, Alessandra Molla, Claudia Vegetti, Marina Zanon, Elena Tassi
Purpose: To assess the role of Apollon in melanoma resistance to intrinsic and extrinsic pathways of apoptosis and to identify strategies to reduce its expression.Experimental Design: Apollon expression was assessed in melanoma cells in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c7e4b6a4d36796611b3832c2e2b141
https://doi.org/10.1158/1078-0432.c.6520007.v1
https://doi.org/10.1158/1078-0432.c.6520007.v1
Autor:
Andrea Anichini, Roberta Mortarini, Alessandro M. Gianni, Carmelo Carlo-Stella, Soldano Ferrone, Michele Milella, Nadia Zaffaroni, Marzia Pennati, Valentina Perotti, Ilaria Bersani, Alessandra Molla, Claudia Vegetti, Marina Zanon, Elena Tassi
PDF file, 1009KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113e42dd1c0ad46223302d5106d48985
https://doi.org/10.1158/1078-0432.22443905.v1
https://doi.org/10.1158/1078-0432.22443905.v1
Autor:
Giacomo Bonitatibus, Giuseppe Luigi Paterlini, Matteo Zanzucchi, Valentina Perotti, Paolo Ernesto Villani
Background: gastric pneumatosis is a rare sign with a primarily radiological diagnosis. In newborn infants, this finding should raise the suspicion of necrotizing enterocolitis, which represents a serious clinical condition with high morbidity and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daf6b68a7b492f7e1aa6ea262b0709eb
https://doi.org/10.21203/rs.3.rs-1973995/v1
https://doi.org/10.21203/rs.3.rs-1973995/v1
Autor:
Roberta Mortarini, Fabio Benigni, Mario Santinami, Paola Baldassari, Alessandra Molla, Gabriella Nicolini, Ilaria Bersani, Andrea Maurichi, Andrea Anichini, Valentina Perotti, Giulia Grazia
Publikováno v:
Oncogene
Discovery of new actionable targets and functional networks in melanoma is an urgent need as only a fraction of metastatic patients achieves durable clinical benefit by targeted therapy or immunotherapy approaches. Here we show that NFATc2 expression
Autor:
A. Anichini, Roberta Mortarini, Valentina Perotti, Ilaria Bersani, Paola Baldassari, Andrea Maurichi, Mario Santinami, Alessandra Molla, Claudia Vegetti
Publikováno v:
Oncogene. 35:2862-2872
Melanoma dedifferentiation, characterized by the loss of MITF and MITF regulated genes and by upregulation of stemness markers as CD271, is implicated in resistance to chemotherapy, target therapy and immunotherapy. The identification of intrinsic me
Autor:
A. Anichini, Valentina Perotti, Claudia Vegetti, Andrea Maurichi, Mario Santinami, Paola Baldassari, Ilaria Bersani, Alessandra Molla, Roberta Mortarini
Publikováno v:
Oncogene
Melanoma dedifferentiation, characterized by the loss of MITF and MITF regulated genes and by upregulation of stemness markers as CD271, is implicated in resistance to chemotherapy, target therapy and immunotherapy. The identification of intrinsic me
Publikováno v:
International Journal of Oncology
Over the last few years, clinical trials with BRAF and mitogen-activated protein/extracellular signal-regulated kinase (MEK) inhibitors have shown significant clinical activity in melanoma, but only a fraction of patients respond to these therapies,
Autor:
Jessica Dal Col, Paola Baldassari, Ilaria Bersani, Andrea Anichini, Valentina Perotti, Elena Tassi, Claudia Vegetti, Roberta Mortarini, Riccardo Dolcetti, Alessandra Molla
Publikováno v:
Journal of Investigative Dermatology. 132(11):2652-2660
The identification of intracellular signaling pathways that promote cell proliferation and resistance to cell death may lead to the development of improved treatment for advanced melanoma. Here we show that the calcineurin/nuclear factor of activated
Autor:
Valentina Perotti, Elena Tassi, Soldano Ferrone, Ilaria Bersani, Marina Zanon, Carmelo Carlo-Stella, Marzia Pennati, Alessandra Molla, Alessandro M. Gianni, Andrea Anichini, Michele Milella, Claudia Vegetti, Roberta Mortarini, Nadia Zaffaroni
Publikováno v:
Clinical Cancer Research. 18:3316-3327
Purpose: To assess the role of Apollon in melanoma resistance to intrinsic and extrinsic pathways of apoptosis and to identify strategies to reduce its expression. Experimental Design: Apollon expression was assessed in melanoma cells in vitro and in
Autor:
Giulia Grazia, Elena Tassi, A. Anichini, Ilaria Bersani, F Benigni, Roberta Mortarini, Valentina Perotti, Carmelo Carlo-Stella, Silvana Canevari, A.M. Gianni, G. Nicolini, I Penna, Claudia Vegetti
Publikováno v:
Cell Death & Disease
Improving treatment of advanced melanoma may require the development of effective strategies to overcome resistance to different anti-tumor agents and to counteract relevant pro-tumoral mechanisms in the microenvironment. Here we provide preclinical