Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Valentina Nieddu"'
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Akademický článek
Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness
Autor: Chiara Battistini, Hilary A. Kenny, Melissa Zambuto, Valentina Nieddu, Valentina Melocchi, Alessandra Decio, Pietro Lo Riso, Carlo Emanuele Villa, Alessia Gatto, Mariacristina Ghioni, Francesca M. Porta, Giuseppe Testa, Raffaella Giavazzi, Nicoletta Colombo, Fabrizio Bianchi, Ernst Lengyel, Ugo Cavallaro
Publikováno v: Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract In ovarian tumors, the omental microenvironment profoundly influences the behavior of cancer cells and sustains the acquisition of stem-like traits, with major impacts on tumor aggressiveness and relapse. Here, we leverage a patient-derived
Externí odkaz: https://doaj.org/article/bbabde530b394fa6aa21455619c9f3bc
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8
Rational design, synthesis, and pharmacological evaluation of a cohort of novel beta-adrenergic receptors ligands enables an assessment of structure-activity relationships
Autor: Jacopo Tricomi, Luca Landini, Valentina Nieddu, Ugo Cavallaro, Jillian G. Baker, Athanasios Papakyriakou, Barbara Richichi
Publikováno v: European journal of medicinal chemistry. 246
Biomedical applications of molecules that are able to modulate β-adrenergic signaling have become increasingly attractive over the last decade, revealing that β-adrenergic receptors (β-ARs) are key targets for a plethora of therapeutic interventio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b824d84d096972c54742aedcf91980c5
https://pubmed.ncbi.nlm.nih.gov/36495629
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9
ATR is a MYB regulated gene and potential therapeutic target in adenoid cystic carcinoma
Autor: Olesya Chayka, Paloma Tejera Nevado, Valentina Nieddu, Gabriele Corda, Göran Stenman, Lilam Rai, Mattias K Andersson, Giovanna Mangiapane, Therese Carlsson, Alexia Tsakaneli, Michael J Wick, Carla Abrahamian, Amanda J. Kedaigle, Arturo Sala
Publikováno v: Oncogenesis
Oncogenesis, Vol 9, Iss 1, Pp 1-10 (2020)
Adenoid cystic carcinoma (ACC) is a rare cancer that preferentially occurs in the head and neck, breast, as well as in other sites. It is an aggressive cancer with high rates of recurrence and distant metastasis. Patients with advanced disease are ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c55e230b49da29550201c9b956d190
https://doi.org/10.1038/s41389-020-0194-3
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10
Repurposing a psychoactive drug for children with cancer: p27Kip1-dependent inhibition of metastatic neuroblastomas by Prozac
Autor: Manuela Iezzi, Sandra Bibbò, Alexia Tsakaneli, Paolo Ciufici, Gianluca Sala, Arturo Sala, Alessia Lamolinara, Emily Capone, Stefania Purgato, Valeria Panella, Michele Sallese, Vincenzo De Laurenzi, Giovanni Perini, Cosmo Rossi, Valentina Nieddu
Publikováno v: Oncogenesis
Oncogenesis, Vol 9, Iss 1, Pp 1-8 (2020)
The MYC family of transcription factors is a major driver of human cancer and potential therapeutic target. However, no clinically viable drugs have been yet developed that are able to directly tackle MYC oncoproteins. In our laboratory, we are explo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9d3c7b151e422abecc5c73ffd5b8c8
http://europepmc.org/articles/PMC6949307
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