Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Valentina M. Fokina"'
Autor:
Jörg König, Xiaoming Wang, Valentina M. Fokina, Masatoshi Tomi, Saki Noguchi, Tatiana N. Nanovskaya, Mahmoud Ahmed, Svetlana Patrikeeva
Publikováno v:
J Pharm Sci
Pravastatin is currently under evaluation for prevention of preeclampsia. Factors contributing to placental disposition of pravastatin are important in assessment of potential undesirable fetal effects. The purpose of this study was to identify the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc1c79032d2a8b72d97bd6a73ff31f1
https://doi.org/10.1016/j.xphs.2021.09.035
https://doi.org/10.1016/j.xphs.2021.09.035
Autor:
Marjan Afrouzian, Tatiana N. Nanovskaya, Mahmoud Ahmed, Valentina M. Fokina, Sherif Z. Abdel-Rahman, Svetlana Patrikeeva, Maged M. Costantine, Meixiang Xu, Rabab Al-Lahham, Wayne G. Fischer
Publikováno v:
Biochemical Pharmacology. 156:467-478
The expression and activity of human placental transporters during pregnancy could be altered by several factors including pathological changes associated with preeclampsia. The aims of this study were to identify the placental efflux transporters in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100cad1f880e3e014bdc316a8cc279f6
https://doi.org/10.1016/j.bcp.2018.09.012
https://doi.org/10.1016/j.bcp.2018.09.012
Autor:
Shannon M. Clark, Sherif Z. Abdel-Rahman, Tatiana N. Nanovskaya, Erik Rytting, Cheryl Oncken, Gary D.V. Hankins, Valentina M. Fokina, Meixiang Xu, Mahmoud Ahmed, Holly West
Publikováno v:
Drug Metabolism and Disposition. 44:1832-1838
Bupropion sustained release is used to promote smoking cessation in males and nonpregnant females. However, its efficacy as a smoking cessation aid during pregnancy is not reported. The pregnancy-associated changes in maternal physiology may alter th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a8bffb01f83517eea71308f4f99896
https://doi.org/10.1124/dmd.116.071530
https://doi.org/10.1124/dmd.116.071530
Autor:
Gary D.V. Hankins, Svetlana Patrikeeva, Cheryl Oncken, Mahmoud Ahmed, Tatiana N. Nanovskaya, Valentina M. Fokina
Publikováno v:
Drug Metabolism Letters. 11
BACKGROUND Bupropion (BUP) has a potential to be an effective pharmacotherapy for smoking cessation during pregnancy. Smoking during pregnancy stimulates placental carbonyl reductases that catalyze the biotransformation of BUP. 4-methylnitrosamino-1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8385e9f5cc32962f0e2d0e16d60f1b30
https://doi.org/10.2174/1872312811666170607095202
https://doi.org/10.2174/1872312811666170607095202
Autor:
Xing Zhang, Xiaoming Wang, Valentina M. Fokina, Tatiana N. Nanovskaya, Gary D.V. Hankins, Mahmoud Ahmed, Daria I. Vernikovskaya
Publikováno v:
Biomedical Chromatography. 29:560-569
This report describes the development and validation of an LC-MS/MS method for the quantitative determination of glyburide (GLB), its five metabolites (M1, M2a, M2b, M3 and M4) and metformin (MET) in plasma and urine of pregnant patients under treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a56d7f23739ad56a4f25e851bbe31d0
https://doi.org/10.1002/bmc.3314
https://doi.org/10.1002/bmc.3314
Autor:
Marxa L. Figueiredo, Forum S. Shah, Jeffrey M. Gimble, Jayne Ellis, Joseph J. Shearer, Valentina M. Fokina, Olga Zolochevska
Publikováno v:
Cytotherapy. 16:346-356
Adipose-derived mesenchymal stromal cells (ASCs) are promising tools for delivery of cytotherapy against cancer. However, ASCs can exert profound effects on biological behavior of tumor cells. Our study aimed to examine the influence of ASCs on gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852f60302f5cf5d7b4d4ee75a60d98df
https://doi.org/10.1016/j.jcyt.2013.11.012
https://doi.org/10.1016/j.jcyt.2013.11.012
Autor:
Gary D.V. Hankins, Valentina M. Fokina, Holly West, Cheryl Oncken, Tatiana N. Nanovskaya, Mahmoud Ahmed
Publikováno v:
Drug and Alcohol Dependence. 171:e150-e151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f8e83bf2feb63b0df6decafd8ef093
https://doi.org/10.1016/j.drugalcdep.2016.08.416
https://doi.org/10.1016/j.drugalcdep.2016.08.416
Autor:
Tatiana N. Nanovskaya, Ronald A. Hill, Olga L. Zharikova, Valentina M. Fokina, Donald R. Mattison, Mahmoud Ahmed, Gary D.V. Hankins
Publikováno v:
Biochemical Pharmacology. 78:1483-1490
One of the factors affecting the pharmacokinetics (PK) of a drug during pregnancy is the activity of hepatic and placental metabolizing enzymes. Recently, we reported on the biotransformation of glyburide by human hepatic and placental microsomes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efcfa6ae78c9d367c5a097eb7b2f576
https://doi.org/10.1016/j.bcp.2009.08.003
https://doi.org/10.1016/j.bcp.2009.08.003
Publikováno v:
Gene Expression Patterns. 4:335-338
We isolated the chicken homologue of opticin (cOptc), a member of the small leucine-rich repeat protein (SLRP) family. cOptc is expressed in the brain and the neural tube from stage 9 onward. At later stages, cOptc is expressed in the ciliary epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4cdbce6d5a952c34124857e93285eb1
https://doi.org/10.1016/j.modgep.2003.10.002
https://doi.org/10.1016/j.modgep.2003.10.002
Autor:
Richard Feinn, Valentina M. Fokina, Shannon M. Clark, Tatiana N. Nanovskaya, Sunil K. Jain, Cheryl Oncken, Gary D.V. Hankins, Mahmoud Ahmed, Holly West
Publikováno v:
American Journal of Obstetrics and Gynecology. 216:420.e1-420.e9
Background Bupropion is used to treat depression during pregnancy. However, its usefulness as a smoking cessation aid for pregnant women is not fully known. Objective The objective of the study was to evaluate the preliminary efficacy of bupropion su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1dce08132e6fa51eb3e68f478225176
https://doi.org/10.1016/j.ajog.2016.11.1036
https://doi.org/10.1016/j.ajog.2016.11.1036