Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Valentina Lacovich"'
Autor:
Ketty Sinigaglia, Anna Cherian, Qiupei Du, Valentina Lacovich, Dragana Vukić, Janka Melicherová, Pavla Linhartova, Lisa Zerad, Stanislav Stejskal, Radek Malik, Jan Prochazka, Nadège Bondurand, Radislav Sedláček, Mary A. O’Connell, Liam P. Keegan
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114618- (2024)
Summary: Adar null mutant mouse embryos die with aberrant double-stranded RNA (dsRNA)-driven interferon induction, and Adar Mavs double mutants, in which interferon induction is prevented, die soon after birth. Protein kinase R (Pkr) is aberrantly ac
Externí odkaz:
https://doaj.org/article/0794de743b15475c9b2dd4e108099a8c
Autor:
Victorio M. Pozo Devoto, Valentina Lacovich, Monica Feole, Pratiksha Bhat, Jaroslav Chovan, Maria Čarna, Isaac G. Onyango, Neda Dragišić, Martina Sűsserová, Martin E. Barrios-Llerena, Gorazd B. Stokin
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-27 (2022)
Abstract Axonal swellings (AS) are one of the neuropathological hallmark of axonal injury in several disorders from trauma to neurodegeneration. Current evidence proposes a role of perturbed Ca2+ homeostasis in AS formation, involving impaired axonal
Externí odkaz:
https://doaj.org/article/bf7fa4016d9d46b798fa0983c59cfed9
Autor:
Kateřina Sheardová, Gustavo Sevlever, Victoria David-Dirgo, Marian Hajduch, Patrick Pirrotte, Clara Limbäck-Stokin, Ritin Sharma, Durga Jha, Robert A. Rissman, Lucia Pertierra, Maria Carna, Richard A. G. Smith, Petr Kaňovsky, Nadine Bakkar, Valentina Lacovich, Hana Markova, Mojmir Vinkler, Giancarlo Forte, Jiri Damborsky, Jan Fric, Silvie Belaskova, Krystine Garcia-Mansfield, Hernan Chaves, Eric B. Dammer, Marketa Nezvedova, Ruben Houbrechts, Gorazd B. Stokin, Nicholas T. Seyfried, Robert Bowser, Martin Vyhnalek, Zuzana Nedelska, Stanislav Katina, Kateřina Texlova, Jan Laczó, Isaac G. Onyango, Thijs Vande Vyvere, Dusan Holub, Zdenek Spacil, Jakub Hort
Publikováno v:
Alzheimer´s & Dementia
Alzheimer’s disease is a neurodegenerative disorder characterized clinically by cognitive decline and pathologically by amyloid deposition and neurofibrillary changes. These neuropathological hallmarks are accompanied by reactive events including m
Autor:
Gorazd B. Stokin, Maria Carna, Valentina Lacovich, Victorio Martin Pozo Devoto, Monica Feole, Katerina Texlova
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Tomás L. Falzone, Luciana Bruno, Maria Carna, Jean-Marc Gallo, Lucas Eneas Cromberg, Gorazd B. Stokin, Matías Alloatti, M. Elena Avale, Giancarlo Forte, Sonia Espindola, Victorio Martin Pozo Devoto, Valentina Lacovich
Publikováno v:
The Journal of Neuroscience. 37:58-69
Tau, as a microtubule (MT)-associated protein, participates in key neuronal functions such as the regulation of MT dynamics, axonal transport, and neurite outgrowth. Alternative splicing of exon 10 in the tau primary transcript gives rise to protein
Autor:
Janina Krell-Roesch, Gorazd B. Stokin, Yonas E. Geda, Pavla Foltynová, Valentina Lacovich, Maria Carna, Victorio Martin Pozo Devoto
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
IBRO Reports. 6:S119
Autor:
Patrizia D’Adamo, Maja Potokar, Robert Zorec, Jernej Jorgačevski, Marko Kreft, Nina Vardjan, Valentina Lacovich, Veronica Bianchi
Publikováno v:
Molecular neurobiology. 54(4)
X-linked non-syndromic intellectual disability (XLID) is a common mental disorder recognized by cognitive and behavioral deficits. Mutations in the brain-specific αGDI, shown to alter a subset of RAB GTPases redistribution in cells, are linked to XL
Publikováno v:
Glia. 60:594-604
Rab4 and Rab5 GTPases are key players in the regulation of endocytosis. Although their role has been studied intensively in the past, it is still unclear how they regulate vesicle mobility. In particular, in astrocytes, the most abundant glial cells
Autor:
Matias Alloatti, Sonia Espindola, Maria Carna, Valentina Lacovich, Giancarlo Forte, Maria Elena Avale, Tomás L. Falzone, Janina Krell-Roesch, Gorazd B. Stokin, Yonas E. Geda
Publikováno v:
Alzheimer's & Dementia. 11