Výsledky vyhledávání - "Valentina Iorio"

Laminin N‐terminus α31 expression during development is lethal and causes widespread tissue‐specific defects in a transgenic mouse model

Autor: Conor J. Sugden, Valentina Iorio, Lee D. Troughton, Ke Liu, Mychel R. P. T. Morais, Rachel Lennon, George Bou‐Gharios, Kevin J. Hamill

Publikováno v: The FASEB Journal. 36

Laminins (LMs) are essential components of all basement membranes where they regulate an extensive array of tissue functions. Alternative splicing from the laminin α3 gene produces a non-laminin but netrin-like protein, Laminin N terminus α31 (LaNt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7b847b7684ae674dbf68708139b6ec
https://doi.org/10.1096/fj.202002588rrr

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Laminin N-terminus α31 expression during development is lethal and causes widespread tissue-specific defects in a transgenic mouse model

Autor: George Bou-Gharios, Lee D. Troughton, Ke Liu, Kevin J. Hamill, Conor J Sugden, Valentina Iorio

Laminins are essential components of all basement membranes where they regulate an extensive array of tissue functions. Alternative splicing from the laminin α3 gene produces a non-laminin but netrin-like protein, Laminin N terminus α31 (LaNt α31)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ae302bc3684f8fb35e4bc43ad455bf6
https://doi.org/10.1101/2020.07.26.221663

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Laminin N-terminus α31 regulates keratinocyte adhesion and migration through modifying the organisation and proteolytic processing of laminin 332

Autor: Valentina Iorio, Liam Shaw, Kazuhiro Yamamoto, Lee D. Troughton, Kevin J. Hamill, Conor J Sugden

Laminin N-terminus α31 (LaNt α31), a member of the laminin superfamily, expressed at low levels in intact epithelium but upregulated during wound repair. Increased expression of LaNt α31 reduced migration rate of corneal keratinocytes through an u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe70131ddf4456d2dac7efeb23814596
https://doi.org/10.1101/617597

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Laminins: Roles and Utility in Wound Repair

Autor: Valentina Iorio, Lee D. Troughton, Kevin J. Hamill

Publikováno v: Advances in Wound Care. 4:250-263

Significance: Laminins are complex extracellular macromolecules that are major players in the control of a variety of core cell processes, including regulating rates of cell proliferation, differentiation, adhesion, and migration. Laminins, and relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6927f607bdffc2e55e4050fe8fe148
https://doi.org/10.1089/wound.2014.0533

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