Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Valentina Farini"'
Autor:
Marta Di Martile, Chiara Gabellini, Marianna Desideri, Marta Matraxia, Valentina Farini, Elisabetta Valentini, Simone Carradori, Cristiana Ercolani, Simonetta Buglioni, Daniela Secci, Massimiliano Andreazzoli, Donatella Del Bufalo, Daniela Trisciuoglio
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-14 (2020)
Abstract Background Understanding the signalling pathways involved in angiogenesis, and developing anti-angiogenic drugs are one of the major focuses on cancer research. Herein, we assessed the effect of CPTH6, a lysine acetyltransferase inhibitor an
Externí odkaz:
https://doaj.org/article/2931084bd4cc42b489a191825c894f44
Autor:
Antonio Sica, Marta Di Martile, Valentina Farini, Francesca Maria Consonni, Daniela Trisciuoglio, Marianna Desideri, Elisabetta Valentini, Simona D'Aguanno, Maria Grazia Tupone, Simonetta Buglioni, Cristiana Ercolani, Enzo Gallo, Bruno Amadio, Irene Terrenato, Maria Laura Foddai, Donatella Del Bufalo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundA bidirectional crosstalk between tumor cells and the surrounding microenvironment contributes to tumor progression and response to therapy. Our previous studies have demonstrated that bcl-2 affects melanoma progression and regulates the tu
Externí odkaz:
https://doaj.org/article/0961c635f0ff4438ae7ac8440e0572b5
Autor:
Fiorenzo Stirpe, Barbara Monti, Elisabetta Polazzi, Maria Giulia Battelli, Andrea Bolognesi, Valentina Farini, Christian D’Alessandro, Antonio Contestabile
Publikováno v:
NeuroToxicology. 28:637-644
Lanceolin and stenodactylin, new type 2 ribosome-inactivating proteins (RIPs) from Adenia plants were recently isolated and their high cytotoxicity was described. Present experiments were performed to investigate the effect of these toxins on neural
Autor:
Matteo Parri, Daniela Massi, Stefania Innocenti, Valentina Farini, Roberto Cecchi, Paola Chiarugi, Silvia Moretti, Gianna Baroni
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 93(3)
Recent studies sight β-adrenergic receptor (AR) antagonists as novel therapeutic agents for melanoma, as they may reduce disease progression. Here within, we evaluated the expression of β-ARs in a series of human cutaneous melanocytic lesions, and
Autor:
Vittoria Scicchitano, Letizia Polito, Luigi Barbieri, Andrea Bolognesi, Valentina Farini, Maria Giulia Battelli
Background The present research studied the interaction of two ribosome-inactivating proteins (RIPs) from Adenia genus with HeLa cells. Namely, lanceolin and stenodactylin were examined in comparison to volkensin, another toxic two-chain RIP from Ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f70f38f2d3819a2c2d9f316691d84c2
http://hdl.handle.net/11585/92183
http://hdl.handle.net/11585/92183
Autor:
Andrea Bolognesi, Pier Luigi Tazzari, Letizia Polito, Massimo Bortolotti, Valentina Farini, Manuela Pedrazzi
Publikováno v:
British journal of haematology. 147(5)
Summary Anti-thymocyte globulins (ATG) are currently used to prevent graft-versushost disease in haematopoietic stem cell transplants from alternative donors and to treat and prevent acute organ rejection after transplantation. Many recent studies ha
Autor:
Valentina Farini, Simona Fermani, Luigi Barbieri, Andrea Bolognesi, Giuseppe Falini, Letizia Polito, Alberto Ripamonti, Giovanna Tosi, Angela Chambery
Publikováno v:
Journal of structural biology. 168(2)
The three-dimensional structures of two type 1 RIPs, bouganin and lychnin, has been solved. Their adenine polynucleotide glycosylase activity was also determined together with other known RIPs: dianthin 30, PAP-R, momordin I, ricin A chain and sapori
Autor:
Luigi Barbieri, Andrea Bolognesi, Valentina Farini, Massimo Bortolotti, Maria Giulia Battelli, Letizia Polito
Ribosome-inactivating protein (RIP)-containing immunotoxins are currently used in clinical trials as anti-tumour drugs, in particular against haematological malignancies. In cell killing-based therapies it is important to identify the death pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57057e99d9b6ae348659734c1bfada18
http://hdl.handle.net/11585/66174
http://hdl.handle.net/11585/66174
Autor:
Paola Strocchi, Fiorenzo Stirpe, Angela Chambery, Massimo Bortolotti, Augusto Parente, Chiara Lubelli, Barbara Dozza, Letizia Polito, Emanuele Pelosi, Luigi Barbieri, Andrea Bolognesi, Valentina Farini
From the caudices of the Passifloraceae Adenia lanceolata and A. stenodactyla, two lectins called lanceolin and stenodactylin, respectively, were purified by affinity chromatography on CL Sepharose 6B. The lectins are glycoproteins with Mr 61,243 (la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534e2ae7d61b8a788a5c01d308b23445
http://hdl.handle.net/11585/48342
http://hdl.handle.net/11585/48342