Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Valentina Condelli"'
Autor:
Paola Mirra, Alessia Parascandolo, Graziella Marino, Federica D’Alterio, Lorenza Zinna, Antonella Desiderio, Giuseppe Patitucci, Giulia Anna Carmen Vita, Valentina Condelli, Sabino Russi, Francesco D’Andrea, Francesco Beguinot, Claudia Miele, Pietro Formisano, Vittoria D’Esposito
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-9 (2024)
Abstract The adipose tissue (AT) surrounding breast cancer (BC) plays a pivotal role in cancer progression and represents an optimal source for new biomarker discovery. The aim of this work was to investigate whether specific AT factors may have prog
Externí odkaz:
https://doaj.org/article/011d546ef709475da91b0b7f85549e11
Autor:
Francesca Pia Caruso, Mario Rosario D’Andrea, Luigi Coppola, Matteo Landriscina, Valentina Condelli, Luigi Cerulo, Guido Giordano, Almudena Porras, Massimo Pancione
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract In addition to being novel biomarkers for poor cancer prognosis, members of Lymphocyte antigen-6 (Ly6) gene family also play a crucial role in avoiding immune responses to tumors. However, it has not been possible to identify the underlying
Externí odkaz:
https://doaj.org/article/86c34b9740db494db12496f33c51bbe9
Publikováno v:
Cancer Cell International, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background BRAF inhibitors are effective anticancer agents in BRAF-mutated melanomas. By contrast, evidences about sensitivity of thyroid carcinomas to BRAF inhibition are conflicting and it has been proposed that BRAF V600E thyroid carcinom
Externí odkaz:
https://doaj.org/article/330f03d64470425c91fabd3ea3fc5e68
Autor:
Giacomo Lettini, Valentina Condelli, Michele Pietrafesa, Fabiana Crispo, Pietro Zoppoli, Francesca Maddalena, Ilaria Laurenzana, Alessandro Sgambato, Franca Esposito, Matteo Landriscina
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7526 (2020)
Wnt/β-Catenin signaling is involved in embryonic development, regeneration, and cellular differentiation and is responsible for cancer stemness maintenance. The HSP90 molecular chaperone TRAP1 is upregulated in 60–70% of human colorectal carcinoma
Externí odkaz:
https://doaj.org/article/19034249c8914e1f8ced42be4cbc536e
Autor:
Fabiana Crispo, Michele Pietrafesa, Valentina Condelli, Francesca Maddalena, Giuseppina Bruno, Annamaria Piscazzi, Alessandro Sgambato, Franca Esposito, Matteo Landriscina
Publikováno v:
Molecules, Vol 25, Iss 16, p 3754 (2020)
Cholangiocarcinoma is a primary malignancy of the biliary tract characterized by late and unspecific symptoms, unfavorable prognosis, and few treatment options. The advent of next-generation sequencing has revealed potential targetable or actionable
Externí odkaz:
https://doaj.org/article/e75a858fb11e46fcaccf73d283e63b70
Autor:
Michele Pietrafesa, Francesca Maddalena, Luciana Possidente, Valentina Condelli, Pietro Zoppoli, Valeria Li Bergolis, Maria Grazia Rodriquenz, Michele Aieta, Giulia Vita, Franca Esposito, Matteo Landriscina
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 145 (2019)
Tumor Necrosis Factor Receptor-Associated Protein 1 (TRAP1) is a heat shock protein 90 (HSP90) molecular chaperone overexpressed in 60−70% human colorectal carcinomas (CRCs) and the co-upregulation of TRAP1 and associated 6-related proteins identif
Externí odkaz:
https://doaj.org/article/c49bfe29f584480eb204861552a4b757
Autor:
Girolamo Spagnoletti, Valeria Li Bergolis, Annamaria Piscazzi, Francesca Giannelli, Valentina Condelli, Lorenza Sisinni, Giuseppe Bove, Giovanni Storto, Matteo Landriscina
Publikováno v:
Tumor Biology, Vol 40 (2018)
Objectives: Preoperative chemoradiation is currently the standard of care in locally advanced rectal carcinoma, even though a subset of rectal tumors does not achieve major clinically meaningful responses upon neoadjuvant chemoradiation. At present,
Externí odkaz:
https://doaj.org/article/233c916fc10e47e5b1426dac20e99b80
Autor:
Fabiana Crispo, Valentina Condelli, Silvia Lepore, Tiziana Notarangelo, Alessandro Sgambato, Franca Esposito, Francesca Maddalena, Matteo Landriscina
Publikováno v:
Cells, Vol 8, Iss 8, p 798 (2019)
Cancer has been considered, for a long time, a genetic disease where mutations in key regulatory genes drive tumor initiation, growth, metastasis, and drug resistance. Instead, the advent of high-throughput technologies has revolutionized cancer rese
Externí odkaz:
https://doaj.org/article/ec58746a3bef40a69e67f50c1771c0a2
Autor:
Valentina Condelli, Fabiana Crispo, Michele Pietrafesa, Giacomo Lettini, Danilo Swann Matassa, Franca Esposito, Matteo Landriscina, Francesca Maddalena
Publikováno v:
Cells, Vol 8, Iss 6, p 532 (2019)
Heat shock protein 90 (HSP90) molecular chaperones are a family of ubiquitous proteins participating in several cellular functions through the regulation of folding and/or assembly of large multiprotein complexes and client proteins. Thus, HSP90s cha
Externí odkaz:
https://doaj.org/article/5fac772dc3f845699d1e379d3306fdc6
Autor:
Lorenza Sisinni, Michele Pietrafesa, Silvia Lepore, Francesca Maddalena, Valentina Condelli, Franca Esposito, Matteo Landriscina
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 4, p 857 (2019)
The unfolded protein response (UPR) is a stress response activated by the accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum (ER) and its uncontrolled activation is mechanistically responsible for several human p
Externí odkaz:
https://doaj.org/article/3c7f4a63a9ee4ae1934744ba1fb1cb39