Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Valentina, Di Biase"'
Autor:
Stefano Lanzetti, Valentina Di Biase
Publikováno v:
Molecules, Vol 27, Iss 4, p 1312 (2022)
Voltage-gated calcium channels (VGCCs) are widely expressed in the brain, heart and vessels, smooth and skeletal muscle, as well as in endocrine cells. VGCCs mediate gene transcription, synaptic and neuronal structural plasticity, muscle contraction,
Externí odkaz:
https://doaj.org/article/db20b592c59847c6b8521455cebacab6
Autor:
Miao Sun, Astrid Rohlmann, Anna Ciuraszkiewicz-Wojciech, Renato Frischknecht, Romy Freund, Sara Enrile Lacalle, Markus Missler, Arthur Bikbaev, Jessica Mitlöhner, Valentina Di Biase, Jennifer Heck, Gerald J. Obermair, Oliver Klatt, Daniele Repetto, Martin Heine, Cornelia Ablinger
Publikováno v:
The Journal of Neuroscience
VGCCs are multisubunit complexes that play a crucial role in neuronal signaling. Auxiliary α2δ subunits of VGCCs modulate trafficking and biophysical properties of the pore-forming α1 subunit and trigger excitatory synaptogenesis. Alterations in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5f494d475d964855445679a6cbe9d8
http://europepmc.org/articles/PMC7326358
http://europepmc.org/articles/PMC7326358
Autor:
Hai Qian, Tommaso Patriarchi, Geoffrey G. Murphy, William A. Catterall, Franz Hofmann, Olivia R. Buonarati, Chao Ye Chen, Erik A. Hammes, Ruth E. Westenbroek, Jennifer L. Price, Yang Kevin Xiang, Zulfiquar A. Malik, Dhrubajyoti Chowdhury, Manuel F. Navedo, Johannes W. Hell, Valentina Di Biase
Publikováno v:
The EMBO journal, vol 35, iss 12
Agonist‐triggered downregulation of β‐adrenergic receptors (ARs) constitutes vital negative feedback to prevent cellular overexcitation. Here, we report a novel downregulation of β2 AR signaling highly specific for Cav1.2. We find that β2‐AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bc0d9c8d7d8a4c47513762c28adede
https://doi.org/10.15252/embj.201593409
https://doi.org/10.15252/embj.201593409
Autor:
Andrea Baessler, Lars S. Maier, Maria Giglberger, Valentina Di Biase, Marcus Fischer, Gabriela Pietrzyk, Teresa Stauber, Theresa Bourjau, Stefan Wagner, Marta Campiglio, Karin P. Hammer, Barbara Schober
Publikováno v:
Biophysical Journal. 118:34a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8420bc9894ce1c6fadb53348bf2df84f
https://doi.org/10.1016/j.bpj.2019.11.366
https://doi.org/10.1016/j.bpj.2019.11.366
Autor:
Alessandra, Folci, Angela, Steinberger, Boram, Lee, Ruslan, Stanika, Susanne, Scheruebel, Marta, Campiglio, Claudia, Ramprecht, Brigitte, Pelzmann, Johannes W, Hell, Gerald J, Obermair, Martin, Heine, Valentina, Di Biase
Publikováno v:
The Journal of Biological Chemistry
L-type voltage-gated CaV1.2 calcium channels (CaV1.2) are key regulators of neuronal excitability, synaptic plasticity, and excitation-transcription coupling. Surface-exposed CaV1.2 distributes in clusters along the dendrites of hippocampal neurons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9ba3d456be45f0d530f58f72705416c
https://pubmed.ncbi.nlm.nih.gov/29180451
https://pubmed.ncbi.nlm.nih.gov/29180451
Autor:
Valentina Di Biase, Gerald J. Obermair, Mathias Gebhart, Bettina Schlick, Prakash Subramanyam, Bernhard E. Flucher, Sabine Baumgartner
Publikováno v:
Journal of Biological Chemistry. 285:5776-5791
Auxiliary beta subunits modulate current properties and mediate the functional membrane expression of voltage-gated Ca(2+) channels in heterologous cells. In brain, all four beta isoforms are widely expressed, yet little is known about their specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f3501141c1066613810c1fc8a14feb
https://doi.org/10.1074/jbc.m109.044271
https://doi.org/10.1074/jbc.m109.044271
Publikováno v:
The Journal of Cell Biology
The functional separation between skeletal and cardiac muscles, which occurs at the threshold between vertebrates and invertebrates, involves the evolution of separate contractile and control proteins for the two types of striated muscles, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba679c5005bd279aef414d30d79557ff
https://doi.org/10.1083/jcb.200503077
https://doi.org/10.1083/jcb.200503077
The β 1a subunit is essential for the assembly of dihydropyridine-receptor arrays in skeletal muscle
Autor:
Clara Franzini-Armstrong, Gerald J. Obermair, Valentina Di Biase, E. Tatiana Felder, Johann Schredelseker, Manfred Grabner, Bernhard E. Flucher
Publikováno v:
Proceedings of the National Academy of Sciences. 102:17219-17224
Homozygous zebrafish of the mutant relaxed ( red ts25 ) are paralyzed and die within days after hatching. A significant reduction of intramembrane charge movements and the lack of depolarization-induced but not caffeine-induced Ca 2+ transients sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6daedf02ee7160f5ac7b6757eae7c0
https://doi.org/10.1073/pnas.0508710102
https://doi.org/10.1073/pnas.0508710102
Publikováno v:
Journal of Cell Science.
Voltage-gated Ca2+ channels are multi-subunit membrane proteins that transduce depolarization into cellular functions such as excitation–contraction coupling in muscle or neurotransmitter release in neurons. The auxiliary β subunits function in me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5398fc66ba124ec11ec5478d6ef024a
https://doi.org/10.1242/jcs.jcs124537
https://doi.org/10.1242/jcs.jcs124537
Autor:
Gerald J. Obermair, Valentina Di Biase, Alessandra Folci, Martin Heine, Angela Steinberger, Ruslan Stanika, Claudia Ramprecht, Marta Campiglio
Publikováno v:
Biophysical Journal. 110:442a
Calcium influx via CaV1.2 L-type voltage gated calcium channels plays a pivotal role in neuronal functions. CaV1.2s distribute in clusters along the dendritic shafts and on the spines of cultured hippocampal neurons. An equilibrium of clustered and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c8e19336ba7ae1a96efc3897d41fc6
https://doi.org/10.1016/j.bpj.2015.11.2379
https://doi.org/10.1016/j.bpj.2015.11.2379