Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Valentina, Bordoni"'
Autor:
Federico Riu, Roberta Ibba, Stefano Zoroddu, Simona Sestito, Michele Lai, Sandra Piras, Luca Sanna, Valentina Bordoni, Luigi Bagella, Antonio Carta
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2223-2240 (2022)
Introduction: Colchicine-binding site inhibitors are some of the most interesting ligands belonging to the wider family of microtubule-destabilising agents.Results: A novel series of 4′-fluoro-substituted ligands (5–13) was synthesised. The antip
Externí odkaz:
https://doaj.org/article/3146be1fa5764644947125552e4d52ee
Autor:
Francesco Spannella, Federico Giulietti, Chiara Di Pentima, Massimiliano Allevi, Valentina Bordoni, Andrea Filipponi, Sara Falzetti, Caterina Garbuglia, Samuele Scorcella, Piero Giordano, Riccardo Sarzani
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundOlder adults are at higher risk of morbidity and mortality for coronavirus disease 2019 (COVID-19). Renin-angiotensin-system inhibitors (RASi) were found to have a neutral or protective effect against mortality in COVID-19 adult patients.Ai
Externí odkaz:
https://doaj.org/article/28ce05b20bcd4b639e06be1bdedb3529
Autor:
Patrizia Virdis, Irene Marchesi, Francesco Paolo Fiorentino, Rossana Migheli, Luca Sanna, Valentina Bordoni, Giorgio Pintore, Grazia Galleri, Maria Rosaria Muroni, Luigi Bagella, Claudio Fozza, Maria Rosaria De Miglio, Luigi Podda
Publikováno v:
Life, Vol 11, Iss 11, p 1128 (2021)
(1) Tomentosin is the most representative sesquiterpene lactone extracted by I. viscosa. Recently, it has gained particular attention in therapeutic oncologic fields due to its anti-tumor properties. (2) In this study, the potential anticancer featur
Externí odkaz:
https://doaj.org/article/bd5baa551e894006aa9844547c6bea88
Autor:
Bagella, Stefano Zoroddu, Luca Sanna, Valentina Bordoni, Weidong Lyu, Gabriele Murineddu, Gerard A. Pinna, Sonia Vanina Forcales, Arturo Sala, David J. Kelvin, Luigi
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 14; Pages: 11263
1,3,4-Oxadiazole derivatives are among the most studied anticancer drugs. Previous studies have analyzed the action of different 1,3,4-oxadiazole derivatives and their effects on cancer cells. This study investigated the characterization of two new c
Autor:
Sanna L, Zeng Tiansheng, David J. Kelvin, Valentina Bordoni, Luigi Bagella, Lyu Weidong, Li Chengxun, Gérard Aimé Pinna, Gabriele Murineddu
Publikováno v:
Journal of Cellular Physiology. 236:3789-3799
1,3,4-Oxadiazole derivatives are widely used in research on antineoplastic drugs. Recently, we discovered a novel unsymmetrical 1,3,4-oxadiazole compound with antiproliferative properties called 2j. To further investigate its possible targets and mol
Autor:
Irene Marchesi, Milena Fais, Francesco Paolo Fiorentino, Valentina Bordoni, Luca Sanna, Stefano Zoroddu, Luigi Bagella
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3581
Rhabdomyosarcoma (RMS) is the most common type of pediatric soft tissue sarcoma. It is classified into two main subtypes: embryonal (eRMS) and alveolar (aRMS). MYC family proteins are frequently highly expressed in RMS tumors, with the highest levels
Autor:
Claudia Fuoco, Marco Orecchioni, Shi Guo, Raquel Sainz, Cansu Gurcan, Darawan Rinchai, Valentina Bordoni, Barbara Zavan, Lucia Gemma Delogu, Alberto Bianco, Açelya Yilmazer, Laura Fusco, Martina Zoccheddu, Cécilia Ménard-Moyon, Davide Bedognetti, Wouter Hendrickx, Raghvendra Mall
Publikováno v:
Nanoscale. 14(2)
We recently found by single-cell mass cytometry that ex vivo human B cells internalize graphene oxide (GO). The functional impact of such uptake on B cells remains unexplored. Here, we disclosed the effects of GO and amino-functionalized GO (GONH2) i
Autor:
Francesco Fiorentino, Luigi Bagella, Maria Rosaria Muroni, Claudio Fozza, Maria Rosaria De Miglio, Valentina Bordoni, Patrizia Virdis, Sanna L, Rossana Migheli, Luigi Podda, Giorgio Antonio Mario Pintore, Grazia Galleri, Irene Marchesi
Publikováno v:
Life
Volume 11
Issue 11
Life, Vol 11, Iss 1128, p 1128 (2021)
Volume 11
Issue 11
Life, Vol 11, Iss 1128, p 1128 (2021)
(1) Tomentosin is the most representative sesquiterpene lactone extracted by I. viscosa. Recently, it has gained particular attention in therapeutic oncologic fields due to its anti-tumor properties. (2) In this study, the potential anticancer featur
Autor:
Maria Rosaria De Miglio, Claudio Fozza, Maria Rosaria Muroni, Giorgio Antonio Mario Pintore, Rossana Migheli, Francesco Fiorentino, Patrizia Virdis, Grazia Galleri, Valentina Bordoni, Sanna L, Irene Marchesi, Luigi Bagella, Luigi Podda
Publikováno v:
International Journal of Molecular Medicine
Multiple myeloma (MM) is an aggressive B cell malignancy. Substantial progress has been made in the therapeutic context for patients with MM, however it still represents an incurable disease due to drug resistance and recurrence. Development of more
Autor:
Stefano Zoroddu, Sanna L, Valentina Bordoni, Weidong Lyu, Serenella Medici, Elisabetta Avitabile, David J. Kelvin, Luigi Bagella
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8621, p 8621 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
The fight against cancer is one of the main challenges for medical research. Recently, nanotechnology has made significant progress, providing possibilities for developing innovative nanomaterials to overcome the common limitations of current therapi