Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Valentin Nelea"'
Autor:
Michael R. Wozny, Valentin Nelea, Iram Fatima S. Siddiqui, Shaynah Wanga, Vivian de Waard, Mike Strauss, Dieter P. Reinhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Microfibril-associated glycoprotein 4 (MFAP4) is a 36-kDa extracellular matrix glycoprotein with critical roles in organ fibrosis, chronic obstructive pulmonary disease, and cardiovascular disorders, including aortic aneurysms. MFAP4 multime
Externí odkaz:
https://doaj.org/article/77dac9f9c47942b7b5f0d8d66ef6937b
Autor:
Wenge Jiang, Dimitra Athanasiadou, Shaodong Zhang, Raffaella Demichelis, Katarzyna B. Koziara, Paolo Raiteri, Valentin Nelea, Wenbo Mi, Jun-An Ma, Julian D. Gale, Marc D. McKee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Induction of complex homochiral architectures by chiral transformation in a mixed enantiomer system has remained largely elusive. Here, the authors report a chirality dominance effect which induces homochiral suprastructures of calcium carbonate by a
Externí odkaz:
https://doaj.org/article/0a9b8d5a89ee4d33900115a5a077ff97
Autor:
Marietta Herrmann, Anne Babler, Irina Moshkova, Felix Gremse, Fabian Kiessling, Ulrike Kusebauch, Valentin Nelea, Rafael Kramann, Robert L Moritz, Marc D McKee, Willi Jahnen-Dechent
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228503 (2020)
The plasma protein fetuin-A mediates the formation of protein-mineral colloids known as calciprotein particles (CPP)-rapid clearance of these CPP by the reticuloendothelial system prevents errant mineral precipitation and therefore pathological miner
Externí odkaz:
https://doaj.org/article/084dc924231d43c7911233b5161a2802
Autor:
Wenge Jiang, Michael S. Pacella, Dimitra Athanasiadou, Valentin Nelea, Hojatollah Vali, Robert M. Hazen, Jeffrey J. Gray, Marc D. McKee
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Chiral structures are formed in numerous processes including biomineralization of calcium carbonate. Here, the authors demonstrate that the chiral, hierarchically-organized architecture of the calcium carbonate mineral, vaterite, can be controlled si
Externí odkaz:
https://doaj.org/article/74444347728740e5bb9ea69e1fc61b9d
Publikováno v:
Crystal Growth & Design. 21:2898-2910
In proteins, phosphorylation of amino acid residues confers unique functions, including mineral-binding properties. For example, osteopontin, an abundant phosphoprotein in many biomineralized tissu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a33d8d1c8b04bd183b798e69dc43db1f
https://doi.org/10.1021/acs.cgd.1c00082
https://doi.org/10.1021/acs.cgd.1c00082
Autor:
Heena Kumra, Valentin Nelea, Jiongci Xu, Hiromi Yanagisawa, Hana Hakami, Dieter P. Reinhardt, Amelie Pagliuzza, Jelena Djokic
Publikováno v:
Proceedings of the National Academy of Sciences. 116:20428-20437
Elastogenesis is a hierarchical process by which cells form functional elastic fibers, providing elasticity and the ability to regulate growth factor bioavailability in tissues, including blood vessels, lung, and skin. This process requires accessory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07855493a38f988605005ef1b913219a
https://doi.org/10.1073/pnas.1901048116
https://doi.org/10.1073/pnas.1901048116
Autor:
Wenge Jiang, Dimitra Athanasiadou, Natalie Reznikov, Yongfeng Hu, Matthew Bilton, Valentin Nelea, Marc D. McKee, Alicia González-Segura, Roland Kröger, Alejandro B. Rodríguez-Navarro
Publikováno v:
Journal of Structural Biology
Mammalian otoconia of the inner ear vestibular apparatus are calcium carbonate-containing mineralized structures critical for maintaining balance and detecting linear acceleration. The mineral phase of otoconia is calcite, which coherently diffracts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dbafabdbeb1f187bb5a1380e53ef74
https://pubmed.ncbi.nlm.nih.gov/32142754
https://pubmed.ncbi.nlm.nih.gov/32142754
Publikováno v:
Bone. 101:37-48
Osteopontin (OPN) belongs to the SIBLING family (Small, Integrin-Binding LIgand N-linked Glycoproteins) of mineral-binding matrix proteins found in bones and teeth. OPN is a well-known inhibitor of matrix mineralization, and enzymatic modification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3feb7499c00fb73da8be92c015d278
https://doi.org/10.1016/j.bone.2017.04.007
https://doi.org/10.1016/j.bone.2017.04.007
Autor:
Jeffrey J. Gray, Robert M. Hazen, Hojatollah Vali, Michael S. Pacella, Dimitra Athanasiadou, Marc D. McKee, Wenge Jiang, Valentin Nelea
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
Chirality is ubiquitous in biology, including in biomineralization, where it is found in many hardened structures of invertebrate marine and terrestrial organisms (for example, spiralling gastropod shells). Here we show that chiral, hierarchically or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0198800711293de6698ae9e74e343ad5
https://doaj.org/article/74444347728740e5bb9ea69e1fc61b9d
https://doaj.org/article/74444347728740e5bb9ea69e1fc61b9d
Autor:
Valentin, Nelea, Dieter P, Reinhardt
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2043
Multidomain matrix-associated zinc extracellular proteases ADAMTS and ADAMTS-like proteins have important biological activities in cells and tissues. Beyond their traditional role in procollagen and von Willebrand factor processing and proteoglycan c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b9bf44c15ecd10ca6a1e7fae844b5f5
https://pubmed.ncbi.nlm.nih.gov/31463915
https://pubmed.ncbi.nlm.nih.gov/31463915