Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Valentin Jakob"'
Autor:
Valentin Jakob, Ben G.E. Zoller, Julia Rinkes, Yingwen Wu, Alexander F. Kiefer, Michael Hust, Saskia Polten, Andrew M. White, Peta J. Harvey, Thomas Durek, David J. Craik, Andreas Siebert, Uli Kazmaier, Martin Empting
Small macrocyclic peptides are promising candidates for new anti-infective drugs. To date, such peptides have been poorly studied in the context of anti-virulence targets. Using phage display and a self-designed peptide library, we identified a cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e738afb2fdc11b9e7e791db3ccd0a1b
Autor:
Walid A. M. Elgaher, Christine Walt, Thomas F. Schulz, Kevin Oberhausen, Valentin Jakob, Martin Empting, Philine Kirsch
Publikováno v:
ACS chemical biology
With the aim to develop novel antiviral agents against Kaposi's Sarcoma Herpesvirus (KSHV), we are targeting the latency-associated nuclear antigen (LANA). This protein plays an important role in viral genome maintenance during latent infection. LANA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37df79907374f794822a7f0988d4701
https://pubmed.ncbi.nlm.nih.gov/31944659
https://pubmed.ncbi.nlm.nih.gov/31944659
Autor:
Gebhardt, Valentin Jakob
Städte gelten als unverzichtbare Verbündete im Kampf gegen den Klimawandel. In dem Diskurs um Nachhaltigkeit und Transformation von Städten sowie ländlichen Räumen gewinnt das noch junge, experimentelle sowie transdisziplinäre Konzept der Reall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b167a139ac673fe8fe68949e785e6e46
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2070
Phage display is a commonly used technology for the screening of large clonal libraries of proteins and peptides. The construction of peptide libraries containing very short sequences, however, poses certain problems for conventional restriction-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::434fb00b25aedaeb0545f5b00489d235
https://pubmed.ncbi.nlm.nih.gov/31625092
https://pubmed.ncbi.nlm.nih.gov/31625092
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998524
Phage display is a commonly used technology for the screening of large clonal libraries of proteins and peptides. The construction of peptide libraries containing very short sequences, however, poses certain problems for conventional restriction-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24fd1d77e05d80719a229b0543882e04
https://doi.org/10.1007/978-1-4939-9853-1_6
https://doi.org/10.1007/978-1-4939-9853-1_6
Autor:
Saskia C. Stein, Valentin Jakob, Martin Empting, Philine Kirsch, Kevin Oberhausen, Thomas F. Schulz, Ivano Cucarro
Publikováno v:
Journal of medicinal chemistry
The latency-associated nuclear antigen (LANA) is required for latent replication and persistence of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. It acts via replicating and tethering the virus episome to the host chromatin and exerts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ab45ba064fa29b5f55d7009f9f856f
https://pubmed.ncbi.nlm.nih.gov/30888817
https://pubmed.ncbi.nlm.nih.gov/30888817
Autor:
Christina S. Müller, Carina Greth, Edward J. Reijerse, Kathrin Stegmaier, Catharina M. Blinn, Antonio J. Pierik, Volker Schünemann, Dominique F. Bechtel, Daili J. A. Netz, Valentin Jakob, Hendrik Auerbach
Publikováno v:
Journal of the American Chemical Society. 141(14)
Apd1, a cytosolic yeast protein, and Aim32, its counterpart in the mitochondrial matrix, have a C-terminal thioredoxin-like ferredoxin (TLF) domain and a widely divergent N-terminal domain. These proteins are found in bacteria, plants, fungi, and uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8dee35fee808013569170701fc8e35
https://pubmed.ncbi.nlm.nih.gov/30879301
https://pubmed.ncbi.nlm.nih.gov/30879301
Autor:
Saskia C. Stein, Julia Rinkes, Valentin Jakob, Martin Empting, Philine Kirsch, Thomas F. Schulz, Aylin Berwanger
Publikováno v:
European journal of medicinal chemistry
France
France
The Latency-associated nuclear antigen (LANA) plays a central role for the latent persistence of the Kaposi's Sarcoma Herpesvirus (KSHV) in the human host and helps to establish lifelong infections. Herein, we report our efforts towards hit-to-lead g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4650314a445bd86fbe9ed97c315668
https://doi.org/10.1016/j.ejmech.2020.112525
https://doi.org/10.1016/j.ejmech.2020.112525
Autor:
Valentin Jakob, Hendrik Auerbach, Dominique F. Bechtel, Volker Schünemann, Daili J. A. Netz, Antonio J. Pierik, Catharina M. Blinn, Christina S. Müller, Carina Greth, Kathrin Stegmaier
Apd1, a cytosolic yeast protein, and Aim32, its counterpart in the mitochondrial matrix, have a C-terminal thioredoxinlike ferredoxin domain and a widely divergent N-terminal domain. These proteins are found in bacteria, plants, fungi and unicellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7a4a151bf4339e93fcf35749ef7de5
https://doi.org/10.26434/chemrxiv.7443971.v1
https://doi.org/10.26434/chemrxiv.7443971.v1
Autor:
Valentin, Jakob
vorgestellt in einer Predigt an dem ausserordentlichen Buss-Bätt- und Dank-Tag, den 8./19. Februar 1756 von Jakob Valentin, Pfarrer zu Luzein in Bündten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dec4abbac9e51a8a1297a52f402ff3fc