A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis

Autor: Brad H. Rovin, Neil Solomons, William F. Pendergraft, Mary Anne Dooley, James Tumlin, Juanita Romero-Diaz, Lidia Lysenko, Sandra V. Navarra, Robert B. Huizinga, Ihar Adzerikho, Elena Mikhailova, Natalya Mitkovskaya, Sergey Pimanov, Nikolay Soroka, Boris Iliev Bogov, Boriana Deliyska, Valentin Ikonomov, Eduard Tilkiyan, Ruth Almeida, Fernando Jimenez, Faud Teran, Irma Tchokhonelidze, Nino Tsiskarishvili, Maynor Herrera Mendez, Nilmo Noel Chavez Perez, Arturo Reyes Loaeza, Sergio Ramon Gutierrez Urena, Juanita Romero Diaz, Rodolfo Araiza Casillas, Magdalena Madero Rovalo, Stanislaw Niemczyk, Antoni Sokalski, Andrzej Wiecek, Marian Klinger, Olga V. Bugrova, Tatiana M. Chernykh, Tatiana R. Kameneva, Lidia V. Lysenko, Tatiana A. Raskina, Olga V. ReshEtko, Natalia N. Vezikova, Tatiana V. Kropotina, Adelya N. Maksudova, Vyacheslav Marasaev, Vladimir A. Dobronravov, Ivan Gordeev, Ashot M. EssAian, Alexey Frolov, Rosa Jelacic, Dragan Jovanovic, Branka Mitic, Gordana Pekovic, Milan Radovic, Goran Radunovic, Patricia Carreira, Federico Diaz Gonzalez, Xavier Fulladosa, Eduardo Ucar, Shamila De Silva, Chula Herath, Anura Hewageegana, Abdul Latiff Mohamed Nazar, A.W.M. Wazil, Iryna Dudar, Olga Godlevska, Svitlana Korneyeva, ViktoriIa Vasylets, Nataliya Sydor, Mykola Kolesnyk, Samir V. Parikh, Nancy Olsen, Ellen M. Ginzler, James A. Tumlin, Amit Saxena, Ramesh Saxena, Richard Alan Lafayette, William Franklin Pendergraft, Amber S. Podoll, Annie A. Arrey-Mensah, Michael Bubb, Jennifer Grossman, Alejandro I. Oporta, Alireza Nami, Md. Mujibur Rahman, Syed Atiqul Haq, Tak Mao Daniel Chan, Mok Mo Yin Temy, Harold Michael P. Gomez, James Bermas, Bernadette Heizel Reyes, Llewellyn T. Hao, Linda Charmaine Roberto, Eric Amante, Allan E. Lanzon, Jung-Yoon Choe, Tae Young Kang, Yon Su Kim, Seung-Geun Lee, Ji Soo Lee, Jason Choo Chon Jun, Archana Vasudevan, Shue-Fen Luo, Tien-Tsai Cheng, Bancha Satirapoj, Kajohnsak Noppakun

Publikováno v: Kidney international. 95(1)

Calcineurin inhibitors added to standard-of-care induction therapy for lupus nephritis (LN) may increase complete renal remission (CRR) rates. The AURA-LV study tested the novel calcineurin inhibitor voclosporin for efficacy and safety in active LN.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36152bc5433d329023ab05a4123eb115
https://pubmed.ncbi.nlm.nih.gov/30904071