Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Valentin Gensbittel"'
Autor:
Maria J. Garcia-Leon, Cristina Liboni, Vincent Mittelheisser, Louis Bochler, Gautier Follain, Clarisse Mouriaux, Ignacio Busnelli, Annabel Larnicol, Florent Colin, Marina Peralta, Naël Osmani, Valentin Gensbittel, Catherine Bourdon, Rafael Samaniego, Angélique Pichot, Nicodème Paul, Anne Molitor, Raphaël Carapito, Martine Jandrot-Perrus, Olivier Lefebvre, Pierre H. Mangin, Jacky G. Goetz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Despite abundant evidence demonstrating that platelets foster metastasis, anti-platelet agents have low therapeutic potential due to the risk of hemorrhages. In addition, whether platelets can regulate metastasis at the late stages of the di
Externí odkaz:
https://doaj.org/article/2da522b6db60448cb066c2604318bcd1
Autor:
Gautier Follain, Naël Osmani, Valentin Gensbittel, Nandini Asokan, Annabel Larnicol, Luc Mercier, Maria Jesus Garcia-Leon, Ignacio Busnelli, Angelique Pichot, Nicodème Paul, Raphaël Carapito, Seiamak Bahram, Olivier Lefebvre, Jacky G. Goetz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Tumor progression and metastatic dissemination are driven by cell-intrinsic and biomechanical cues that favor the growth of life-threatening secondary tumors. We recently identified pro-metastatic vascular regions with blood flow profiles th
Externí odkaz:
https://doaj.org/article/6130e5f27801400da5a956453d118a77
Autor:
Gautier Follain, Naël Osmani, Valentin Gensbittel, Nandini Asokan, Annabel Larnicol, Luc Mercier, Maria Jesus Garcia‑Leon, Ignacio Busnelli, Angelique Pichot, Nicodème Paul, Raphaël Carapito, Seiamak Bahram, Olivier Lefebvre, Jacky G. Goetz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/45888bde363441b999315d85c5cf9431
Autor:
Valentin Gensbittel, Sébastien Harlepp, Ignacio Busnelli, Jacky G. Goetz, Jochen Guck, Martin Kräter
Publikováno v:
Developmental Cell. 56:164-179
The most dangerous aspect of cancer lies in metastatic progression. Tumor cells will successfully form life-threatening metastases when they undergo sequential steps along a journey from the primary tumor to distant organs. From a biomechanics standp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4a529eca175a99ed06bf45ff54f449
https://doi.org/10.1016/j.devcel.2020.10.011
https://doi.org/10.1016/j.devcel.2020.10.011
Publikováno v:
Comptes rendus biologies. 344(3)
Metastatic progression, which begins with the invasion and migration of tumor cells from a primary tumor, marks a major turning point in the evolution of cancer. Indeed, it eventually leads to the formation of secondary tumors, the metastases, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1500180127978aa169d9558b9b15115c
https://pubmed.ncbi.nlm.nih.gov/35786629
https://pubmed.ncbi.nlm.nih.gov/35786629
Autor:
Naël, Osmani, Gautier, Follain, Valentin, Gensbittel, María Jesús, García-León, Sébastien, Harlepp, Jacky G, Goetz
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2294
Cancer metastasis is a multistep process during which tumor cells leave the primary tumor mass and form distant secondary colonies that are lethal. Circulating tumor cells (CTCs) are transported by body fluids to reach distant organs, where they will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ad2437e453e15dd157c6ab6083fb66a
https://pubmed.ncbi.nlm.nih.gov/33742397
https://pubmed.ncbi.nlm.nih.gov/33742397
Publikováno v:
Trends in Cancer
Trends in Cancer, 2021, 7, pp.9-11. ⟨10.1016/j.trecan.2020.11.003⟩
Trends in Cancer, Cell Press, 2021, 7, pp.9-11. ⟨10.1016/j.trecan.2020.11.003⟩
Trends in Cancer, 2021, 7, pp.9-11. ⟨10.1016/j.trecan.2020.11.003⟩
Trends in Cancer, Cell Press, 2021, 7, pp.9-11. ⟨10.1016/j.trecan.2020.11.003⟩
Clustering of tumor cells is known to grant superior metastatic efficiency compared with single cells. However, the mechanisms involved remain elusive. Reporting in Cell, Wrenn et al. describe how sealed intercellular compartments, nanolumina, are us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9330dd2e5d0c63dc6105bcaffc7c11
https://pubmed.ncbi.nlm.nih.gov/33262057
https://pubmed.ncbi.nlm.nih.gov/33262057
Autor:
Gautier, Follain, Valentin, Gensbittel, Benjamin, Mary, Olivier, Lefebvre, Sébastien, Harlepp, Vincent, Hyenne, Jacky G, Goetz
Publikováno v:
Medecine sciences : M/S. 36(10)
Metastases are the main cause of cancer-related deaths. The chain of events leading to their development is called "the metastatic cascade". The biological and biochemical aspects of this process have been well studied but the importance of biomechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a6418d6743445590de4dc9aa8e2eeab
https://pubmed.ncbi.nlm.nih.gov/33026329
https://pubmed.ncbi.nlm.nih.gov/33026329
Autor:
Benjamin Mary, Gautier Follain, Jacky G. Goetz, Sébastien Harlepp, Olivier Lefebvre, Valentin Gensbittel, Vincent Hyenne
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2020, 36 (10), pp.872-878. ⟨10.1051/medsci/2020158⟩
médecine/sciences, 2020, 36 (10), pp.872-878. ⟨10.1051/medsci/2020158⟩
médecine/sciences, EDP Sciences, 2020, 36 (10), pp.872-878. ⟨10.1051/medsci/2020158⟩
médecine/sciences, 2020, 36 (10), pp.872-878. ⟨10.1051/medsci/2020158⟩
International audience; La suite d’évènements menant à l’apparition de métastases est appelée « cascade métastatique ». L’étude récente de la composante biomécanique de cette cascade a révélé le rôle central des liquides biologiq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa5aa20beb8f3978f535d54135b169e
https://hal.archives-ouvertes.fr/hal-02960803/document
https://hal.archives-ouvertes.fr/hal-02960803/document
Autor:
Sylvie Begin-Colin, C.J.R. Wells, Damien Mertz, Valentin Gensbittel, O. Bringel, Jacky G. Goetz, B. Li, Sébastien Harlepp, Mariana Tasso, Dominique Begin
Publikováno v:
Materials Today Chemistry
Materials Today Chemistry, Elsevier, 2020, 17, pp.100308. ⟨10.1016/j.mtchem.2020.100308⟩
Materials Today Chemistry, 2020, 17, pp.100308. ⟨10.1016/j.mtchem.2020.100308⟩
Materials Today Chemistry, Elsevier, 2020, 17, ⟨10.1016/j.mtchem.2020.100308⟩
Materials Today Chemistry, Elsevier, 2020, 17, pp.100308. ⟨10.1016/j.mtchem.2020.100308⟩
Materials Today Chemistry, 2020, 17, pp.100308. ⟨10.1016/j.mtchem.2020.100308⟩
Materials Today Chemistry, Elsevier, 2020, 17, ⟨10.1016/j.mtchem.2020.100308⟩
Among smart activable nanomaterials used for nanomedicine applications, carbon-based nano composites are well known to ensure phototherapy while their use for controlled drug delivery is still rarely investigated. In this work, original hybrid mesopo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ece314c6579c45d15a2dd75b899e7c6
https://hal.archives-ouvertes.fr/hal-03438335
https://hal.archives-ouvertes.fr/hal-03438335