Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Valentin Derangere"'
Autor:
Nicolas Roussot, Marion Thibaudin, Jean-David Fumet, Susy Daumoine, Léa Hampe, Cédric Rébé, Emeric Limagne, Aurélie Lagrange, Victor Herreros, Julie Lecuelle, Hugo Mananet, Alis Ilie, David Rageot, Romain Boidot, Vincent Goussot, Anthony Comte, Pierre Jacob, Françoise Beltjens, Anthony Bergeron, Céline Charon-Barra, Laurent Arnould, Valentin Derangère, Sylvain Ladoire, Caroline Truntzer, François Ghiringhelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
A patient with a PD-L1-negative, TMB-low, KEAP1/STK11 co-mutated metastatic non-small cell lung cancer (NSCLC) experienced a multisite radiological progression at 3 months after initiation of chemoimmunotherapy as first-line treatment for metastatic
Externí odkaz:
https://doaj.org/article/720f9ebdb12b41d5a9b653e489118e2d
Autor:
Julie Lecuelle, Caroline Truntzer, Debora Basile, Luigi Laghi, Luana Greco, Alis Ilie, David Rageot, Jean-François Emile, Fréderic Bibeau, Julien Taïeb, Valentin Derangere, Come Lepage, François Ghiringhelli
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105207- (2024)
Summary: Background: T-cell immune infiltrates are robust prognostic variables in localised colon cancer. Evaluation of prognosis using artificial intelligence is an emerging field. We evaluated whether machine learning analysis improved prediction o
Externí odkaz:
https://doaj.org/article/f4866831da2d49b389ebad9f61f0d2b7
Autor:
Violaine Randrian, Amandine Desette, Sheik Emambux, Valentin Derangere, Pauline Roussille, Eric Frouin, Julie Godet, Lucie Karayan-Tapon, François Ghiringhelli, David Tougeron
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Incidence of brain metastases has increased in patients with colorectal cancer (CRC) as their survival has improved. CD3 T-cells and, lately, DGMate (DiGital tuMor pArameTErs) score, have been identified as prognostic factors in locally advanced CRC.
Externí odkaz:
https://doaj.org/article/e7310c5e2ab348bfbedccdf3f9f9c303
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background The prognosis of early breast cancer is linked to clinic-pathological stage and the molecular characteristics of intrinsic tumor cells. In some patients, the amount and quality of tumor-infiltrating immune cells appear to affect long term
Externí odkaz:
https://doaj.org/article/472e9ebb1b464a509fd3fa9a3a317629
Autor:
Valentin Derangere, Marion Thibaudin, Fanny Chalmin, Cédric Rébé, Julie Niogret, Hélène Berger, Romain Mary, Elise Ballot, Christophe Hibos, Léa Hampe, David Rageot, Théo Accogli, Philippe Joubert, James Harker, Frederique Vegran
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background T follicular helper cells (Tfh) are essential to shape B cell response during germinal center formation. Tfh accumulation has been reported in various human cancers, with positive or negative prognostic roles. However, the mechanisms expla
Externí odkaz:
https://doaj.org/article/eb04733954c348f69ad8e9ceaa3f46ea
Autor:
Mathieu Grapin, Corentin Richard, Emeric Limagne, Romain Boidot, Véronique Morgand, Aurélie Bertaut, Valentin Derangere, Pierre-Antoine Laurent, Marion Thibaudin, Jean David Fumet, Gilles Crehange, François Ghiringhelli, Céline Mirjolet
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Purpose/objective Radiotherapy (RT) induces an immunogenic antitumor response, but also some immunosuppressive barriers. It remains unclear how different fractionation protocols can modulate the immune microenvironment. Clinical studies are
Externí odkaz:
https://doaj.org/article/9cc548f2892b456d9985f8bd2567842d
Autor:
Fanny Ledys, Quentin Klopfenstein, Caroline Truntzer, Laurent Arnould, Julie Vincent, Leila Bengrine, Romain Remark, Romain Boidot, Sylvain Ladoire, Francois Ghiringhelli, Valentin Derangere
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background T lymphocytes and HLA expression on tumor cell both influence prognostic of localized colorectal cancer, but their role following chemotherapy in patients with liver metastatic colorectal cancer (mCRC) was not addressed. Methods O
Externí odkaz:
https://doaj.org/article/f4b2d253e348427284501126f50ab4c2
Autor:
Marine Cordonnier, Charlée Nardin, Gaëtan Chanteloup, Valentin Derangere, Marie-Paule Algros, Laurent Arnould, Carmen Garrido, François Aubin, Jessica Gobbo
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
In the era of immunotherapies there is an urgent need to implement the use of circulating biomarkers in clinical practice to facilitate personalized therapy and to predict treatment response. We conducted a prospective study to evaluate the usefulnes
Externí odkaz:
https://doaj.org/article/a27ea3673fb34ec1abfe649e00b7fbb1
Autor:
Coralie Schoumacher, Valentin Derangère, Gwladys Gaudillière-Le Dain, Titouan Huppe, David Rageot, Alis Ilie, Angélique Vienot, Christophe Borg, Franck Monnien, Frederic Bibeau, Caroline Truntzer, François Ghiringhelli
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTStratification of the prognosis of pancreatic cancer (PDAC) patients treated by surgery is based solely on clinical variables, such as tumor stage and node status. The development of biomarkers of relapse is needed, especially to drive admini
Externí odkaz:
https://doaj.org/article/d7de998b11554bb3986b1833080f8892
Autor:
Benoit Mazel, Geoffrey Bertolone, Amandine Baurand, Elodie Cosset, Caroline Sawka, Marion Robert, Elodie Gautier, Allan Lançon, Manon Réda, Laure Favier, Valentin Dérangère, Corentin Richard, Christine Binquet, Romain Boidot, Vincent Goussot, Juliette Albuisson, François Ghiringhelli, Laurence Faivre, Sophie Nambot
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18786-18796 (2023)
Abstract Introduction With the emergence of targeted therapies, there is a need to accurately identify more tumor biomarkers. The EXOMA trial was designed to offer tumor and germline exome sequencing (ES) to patients with solid malignant tumors and f
Externí odkaz:
https://doaj.org/article/1d715b84577b4084b82c16565b999548