Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Valentin David"'
Autor:
Marta Martinez-Calle, Guillaume Courbon, Bridget Hunt-Tobey, Connor Francis, Jadeah Spindler, Xueyan Wang, Luciene M. dos Reis, Carolina S.W. Martins, Isidro B. Salusky, Hartmut Malluche, Thomas L. Nickolas, Rosa M.A. Moyses, Aline Martin, Valentin David
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 11 (2023)
Renal osteodystrophy (ROD) is a disorder of bone metabolism that affects virtually all patients with chronic kidney disease (CKD) and is associated with adverse clinical outcomes including fractures, cardiovascular events, and death. In this study, w
Externí odkaz:
https://doaj.org/article/ca73d3f493094b778ce314fb3c6e600d
Autor:
Guillaume Courbon, Connor Francis, Claire Gerber, Samantha Neuburg, Xueyan Wang, Emily Lynch, Tamara Isakova, Jodie L. Babitt, Myles Wolf, Aline Martin, Valentin David
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract Bone-produced fibroblast growth factor 23 (FGF23) increases in response to inflammation and iron deficiency and contributes to cardiovascular mortality in chronic kidney disease (CKD). Neutrophil gelatinase-associated lipocalin (NGAL or lipo
Externí odkaz:
https://doaj.org/article/3dd04b3da81248089604b6e092e74df0
Autor:
Alexia Roux, Valentin David, Sylvia Bardet M, Emilie Auditeau, Sylvaine Durand Fontanier, Abdelkader Taibi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
SynopsisC-reactive protein (CRP), white blood cells and procalcitonin (PCT) participate in the systemic response to inflammation and increase after postoperative infective complications. Postoperative complications after CRS and HIPEC could be predic
Externí odkaz:
https://doaj.org/article/f779710bbc394d8aa919ccd2f93b0c83
Publikováno v:
JBMR Plus, Vol 5, Iss 8, Pp n/a-n/a (2021)
ABSTRACT Sodium‐glucose cotransporter 2 (SGLT2) inhibitors improve kidney and cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM). However, bone fragility has emerged as a side effect in some but not in all human studies. Becau
Externí odkaz:
https://doaj.org/article/e165f9e3d6e8435e9d0db1c4ea08fc67
Autor:
Anthony A Portale, Martin Y H Zhang, Valentin David, Aline Martin, Yan Jiao, Weikuan Gu, Farzana Perwad
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142924 (2015)
Fibroblast growth factor 23 (FGF23) is a potent regulator of phosphate (Pi) and vitamin D homeostasis. The transcription factor, early growth response 1 (egr-1), is a biomarker for FGF23-induced activation of the ERK1/2 signaling pathway. We have sho
Externí odkaz:
https://doaj.org/article/ef41c5028d2e46ddab769e37198c75ab
Autor:
Yueying Zhang, Jinsong Huang, Yan Jiao, Valentin David, Mehmet Kocak, Esra Roan, Denis Di’Angelo, Lu Lu, Karen A. Hasty, Weikuan Gu
Publikováno v:
The Scientific World Journal, Vol 2015 (2015)
We examined the bone properties of BXD recombinant inbred (RI) mice by analyzing femur and tibia and compared their phenotypes of different compartments. 46 BXD RI mouse strains were analyzed including progenitor C57BL/6J (n=16) and DBA/2J (n=15) and
Externí odkaz:
https://doaj.org/article/27f757c9c7a8438ebb0a83b3539cc156
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46038 (2012)
Conditional deletion of Pkd1 in osteoblasts using either Osteocalcin(Oc)-Cre or Dmp1-Cre results in defective osteoblast-mediated postnatal bone formation and osteopenia. Pkd1 is also expressed in undifferentiated mesenchyme that gives rise to the os
Externí odkaz:
https://doaj.org/article/1ddaf35439e04e5c9635382bbf7ef24b
Autor:
Bing Dai, Valentin David, Aline Martin, Jinsong Huang, Hua Li, Yan Jiao, Weikuan Gu, L Darryl Quarles
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44161 (2012)
Elevations of circulating Fibroblast growth factor 23 (FGF23) are associated with adverse cardiovascular outcomes and progression of renal failure in chronic kidney disease (CKD). Efforts to identify gene products whose transcription is directly regu
Externí odkaz:
https://doaj.org/article/9fababf5bf4d41b9887cd45ca8080baf
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15240 (2010)
Pkd1 localizes to primary cilia in osteoblasts and osteocytes. Targeted deletion of Pkd1 in osteoblasts results in osteopenia and abnormalities in Runx2-mediated osteoblast development. Kif3a, an intraflagellar transport protein required for cilia fu
Externí odkaz:
https://doaj.org/article/e5ec2ecaa78b456f8754666cf72fac69
Autor:
Moraga, Greco, Mut, Vicent, Girardelo, Jeferson, Mazzouji, Farid, Valentín, David, Egusquiza, Mònica, Egusquiza, Eduard, Presas, Alexandre
Publikováno v:
In Engineering Failure Analysis June 2024 160