Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Valentin Bon-Baret"'
Autor:
Kim Valette, Zhonglin Li, Valentin Bon-Baret, Arnaud Chignon, Jean-Christophe Bérubé, Aida Eslami, Jennifer Lamothe, Nathalie Gaudreault, Philippe Joubert, Ma’en Obeidat, Maarten van den Berge, Wim Timens, Don D. Sin, David C. Nickle, Ke Hao, Catherine Labbé, Krystelle Godbout, Andréanne Côté, Michel Laviolette, Louis-Philippe Boulet, Patrick Mathieu, Sébastien Thériault, Yohan Bossé
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Kim Valette et al. perform a genomic study on asthma integrating genome-wide association study, functional mapping using lung and blood transcriptome-wide profiles, as well as Mendelian randomization. They show candidate causal genes expressed in lun
Externí odkaz:
https://doaj.org/article/b3d76be062194736bdde905088a0270a
Autor:
Arnaud Chignon, Déborah Argaud, Marie-Chloé Boulanger, Ghada Mkannez, Valentin Bon-Baret, Zhonglin Li, Sébastien Thériault, Yohan Bossé, Patrick Mathieu
Publikováno v:
PLoS Genetics, Vol 18, Iss 1, p e1010010 (2022)
Calcific aortic valve disease (CAVD) is characterized by a fibrocalcific process. The regulatory mechanisms that drive the fibrotic response in the aortic valve (AV) are poorly understood. Long noncoding RNAs derived from super-enhancers (lncRNA-SE)
Externí odkaz:
https://doaj.org/article/a52b63d858e342a38c2ef01cec081680
Autor:
Arnaud Chignon, Mickael Rosa, Marie-Chloé Boulanger, Déborah Argaud, Romain Devillers, Valentin Bon-Baret, Ghada Mkannez, Zhonglin Li, Anne Rufiange, Nathalie Gaudreault, David Gosselin, Sébastien Thériault, Yohan Bossé, Patrick Mathieu
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102241- (2021)
Summary: Genome-wide association studies for calcific aortic valve stenosis (CAVS) previously reported strong signal for noncoding variants at 1p21.2. Previous study using Mendelian randomization suggested that the locus controls the expression of PA
Externí odkaz:
https://doaj.org/article/e657ef70b6e54d1397b274d199c5df61
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:1804-1807
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54989f4fb252bc001d16646eed5d6245
https://doi.org/10.1161/atvbaha.120.314733
https://doi.org/10.1161/atvbaha.120.314733
Autor:
Valentin Bon-Baret, Patrick Mathieu, Marie-Chloé Boulanger, Deborah Argaud, Zhonglin Li, Benoit J. Arsenault, Sébastien Thériault, Arnaud Chignon, Yohan Bossé
Publikováno v:
Circ Genom Precis Med
Background: Randomized clinical trials indicate that the immune response plays a significant role in coronary artery disease (CAD), a disorder impacting the lifespan potential. However, the identification of targets critical to the immune response in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ee9cdfcf0eb29b565a9fbb5048e4ae
https://doi.org/10.1161/circgen.120.003196
https://doi.org/10.1161/circgen.120.003196
Autor:
Nathalie Gaudreault, David Gosselin, Sébastien Thériault, Romain Devillers, Patrick Mathieu, Ghada Mkannez, Zhonglin Li, Deborah Argaud, Marie-Chloé Boulanger, Arnaud Chignon, Anne Rufiange, Yohan Bossé, Valentin Bon-Baret, Mickael Rosa
Publikováno v:
iScience
iScience, Vol 24, Iss 3, Pp 102241-(2021)
iScience, Vol 24, Iss 3, Pp 102241-(2021)
Summary Genome-wide association studies for calcific aortic valve stenosis (CAVS) previously reported strong signal for noncoding variants at 1p21.2. Previous study using Mendelian randomization suggested that the locus controls the expression of PAL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd8bf589241e468a8b2580a7c8c9364
http://europepmc.org/articles/PMC7970363
http://europepmc.org/articles/PMC7970363
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 41(1)
Mineralization of cardiovascular structures including blood vessels and heart valves is a common feature. We postulate that ectopic mineralization is a response-to-injury in which signals delivered to cells trigger a chain of events to restore and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b09d408f9e68d0bcc4e8326d8ce4b2
https://pubmed.ncbi.nlm.nih.gov/33232199
https://pubmed.ncbi.nlm.nih.gov/33232199
Autor:
Jennifer Lamothe, Krystelle Godbout, Aida Eslami, Kim Valette, David C. Nickle, Arnaud Chignon, Andréanne Côté, Maarten van den Berge, Don D. Sin, Patrick Mathieu, Michel Laviolette, Zhonglin Li, Valentin Bon-Baret, Ke Hao, Yohan Bossé, Nathalie Gaudreault, Catherine Labbé, Jean-Christophe Bérubé, Philippe Joubert, Ma'en Obeidat, Sébastien Thériault, Louis-Philippe Boulet, Wim Timens
To identify susceptibility loci and candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mappin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5dfe91f5e9c57dbf62c71df0df0cea
https://doi.org/10.21203/rs.3.rs-68257/v1
https://doi.org/10.21203/rs.3.rs-68257/v1
Autor:
Ma'en Obeidat, Krystelle Godbout, Kim Valette, Philippe Joubert, Louis-Philippe Boulet, Sébastien Thériault, Maarten van den Berge, Patrick Mathieu, Arnaud Chignon, Catherine Labbé, Valentin Bon-Baret, Jean-Christophe Bérubé, Jennifer Lamothe, Nathalie Gaudreault, Aida Eslami, David C. Nickle, Ke Hao, Don D. Sin, Zhonglin Li, Michel Laviolette, Wim Timens, Andréanne Côté, Yohan Bossé
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mapping through transcriptome-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efe5da760f0db267eb48e7d033d1f0e
https://pubmed.ncbi.nlm.nih.gov/34103634
https://pubmed.ncbi.nlm.nih.gov/34103634