Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Valentin, Soulard"'
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Akademický článek
Wnt-pathway inhibitors with selective activity against triple-negative breast cancer: From thienopyrimidine to quinazoline inhibitors
Autor: Cédric Boudou, Luce Mattio, Alexey Koval, Valentin Soulard, Vladimir L. Katanaev
Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)
The Wnt-pathway has a critical role in development and tissue homeostasis and has attracted increased attention to develop anticancer drugs due to its aberrant activation in many cancers. In this study, we identified a novel small molecule series wit
Externí odkaz: https://doaj.org/article/1e0f46bf8217440aaeb16566fa049e38
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3
Radical Deuteration with D2O: Catalysis and Mechanistic Insights
Autor: Denis Patrick Vollmar, Giorgio Villa, Valentin Soulard, Philippe Renaud
Publikováno v: Journal of the American Chemical Society. 140:155-158
Selective incorporation of deuterium atoms into molecules is of high interest for labeling purposes and for optimizing properties of drug candidates. A mild and environmentally benign method for the deuteration of alkyl iodides via radical pathway us
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99ff856393662004ae276542d4d620af
https://doi.org/10.1021/jacs.7b12105
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9
Radical Deuteration with D
Autor: Valentin, Soulard, Giorgio, Villa, Denis Patrick, Vollmar, Philippe, Renaud
Publikováno v: Journal of the American Chemical Society. 140(1)
Selective incorporation of deuterium atoms into molecules is of high interest for labeling purposes and for optimizing properties of drug candidates. A mild and environmentally benign method for the deuteration of alkyl iodides via radical pathway us
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c4df3812bd99283e723cb61f8c996fd
https://pubmed.ncbi.nlm.nih.gov/29240406
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10
Effect of Brønsted acids on the thiophenol-mediated radical addition-translocation-cyclization process for the preparation of pyrrolidine derivatives
Autor: Valentin Soulard, Philippe Renaud, Fabrice Dénès
Publikováno v: Soulard, Valentin; Dénès, Fabrice; Renaud, Philippe (2016). Effect of Brønsted acids on the thiophenol-mediated radical addition–translocation–cyclization process for the preparation of pyrrolidine derivatives. Free radical research, 50(S1), S2-S5. Taylor & Francis 10.1080/10715762.2016.1223294
Free Radical Research
Free Radical Research, 2016, 50 (1), pp.S2-S5. ⟨10.1080/10715762.2016.1223294⟩
A thiophenol-mediated method for the conversion of propargylamines to pyrrolidines under acidic conditions is described. This cascade reaction involves addition of a thiyl radical to the terminal alkyne followed by a 1,5-hydrogen transfer (radical tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215e08bb5e6b2bc4e408f86510e8fd53
https://pubmed.ncbi.nlm.nih.gov/27684302
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