The ChoCO-W prospective observational global study: Does COVID-19 increase gangrenous cholecystitis?

Autor: De Simone B; Department of Emergency, Digestive and Metabolic Minimally Invasive Surgery, Poissy and Saint Germain en Laye Hospitals, Poissy, France. desimone.belinda@gmail.com., Abu-Zidan FM; The Research Office, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates., United Arab Emirates University, Al-Ain, UAE., Chouillard E; Department of Emergency, Digestive and Metabolic Minimally Invasive Surgery, Poissy and Saint Germain en Laye Hospitals, Poissy, France., Di Saverio S; Department of General Surgery, Santa Maria del Soccorso Hospital, San Benedetto del Tronto, Ascoli Piceno, Italy., Sartelli M; Department of General Surgery, Macerata Hospital, Macerata, Italy., Podda M; Department of Surgical Science, University of Cagliari, Cagliari, Italy., Gomes CA; Faculdade de Ciência Médicas e da Saúde de Juiz de Fora, Hospital Universitario Terezinha de Jesus (SUPREMA), Juiz de Fora, Brazil., Moore EE; Ernest E. Moore Shock Trauma Center at Denver Health, Denver, CO, USA., Moug SJ; Department of Surgery, Royal Alexandra Hospital, Paisley and Golden Jubilee National Hospital, University of Glasgow, Glasgow, Scotland., Ansaloni L; Department of General Surgery, University Hospital of Pavia, Pavia, Italy., Kluger Y; Department of General Surgery, The Rambam Academic Hospital, Haifa, Israel., Coccolini F; Department of General and Emergency Surgery, University Hospital of Pisa, Pisa, Italy., Landaluce-Olavarria A; Alfredo- Espinosa Urduliz Hospital, Urduliz, Spain., Estraviz-Mateos B; Alfredo- Espinosa Urduliz Hospital, Urduliz, Spain., Uriguen-Etxeberria A; Alfredo- Espinosa Urduliz Hospital, Urduliz, Spain., Giordano A; General Surgery Unit ASL Toscana Centro, Santo Stefano Hospital, Prato, Italy., Luna AP; Universidad de Sucre, Clínica Santa María, Sincelejo, Colombia., Amín LAH; Universidad de Sucre, Clínica Santa María, Sincelejo, Colombia., Hernández AMP; Universidad de Sucre, Clínica Santa María, Sincelejo, Colombia., Shabana A; Emergency Surgery Department, John Radcliffe Hospital, Oxford, UK., Dzulkarnaen ZA; Department of Surgery, School of Medical Sciences and Hospital USM, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Othman MA; Department of Surgery, School of Medical Sciences and Hospital USM, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Sani MI; Department of Surgery, School of Medical Sciences and Hospital USM, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia., Balla A; UOC of General and Minimally Invasive Surgery, Hospital 'San Paolo', Largo Donatori del Sangue 1, 00053, Civitavecchia, Rome, Italy., Scaramuzzo R; UOC of General and Minimally Invasive Surgery, Hospital 'San Paolo', Largo Donatori del Sangue 1, 00053, Civitavecchia, Rome, Italy., Lepiane P; UOC of General and Minimally Invasive Surgery, Hospital 'San Paolo', Largo Donatori del Sangue 1, 00053, Civitavecchia, Rome, Italy., Bottari A; SOD Chirurgia dell'Apparato Digerente, AOU Careggi, Florence, Italy., Staderini F; SOD Chirurgia dell'Apparato Digerente, AOU Careggi, Florence, Italy., Cianchi F; SOD Chirurgia dell'Apparato Digerente, AOU Careggi, Florence, Italy., Cavallaro A; Department of Surgery, University of Catania, Policlinico 'G. Rodolico - San Marco' Hospital, Catania, Italy., Zanghì A; Department of Surgery, University of Catania, Policlinico 'G. Rodolico - San Marco' Hospital, Catania, Italy., Cappellani A; Department of Surgery, University of Catania, Policlinico 'G. Rodolico - San Marco' Hospital, Catania, Italy., Campagnacci R; U.O.C. of General Surgery, 'Carlo Urbani' Hospital, Jesi, AN, Italy., Maurizi A; U.O.C. of General Surgery, 'Carlo Urbani' Hospital, Jesi, AN, Italy., Martinotti M; Hospital 'Istituto Città di Pavia', Pavia, Italy., Ruggieri A; Hospital 'Istituto Città di Pavia', Pavia, Italy., Jusoh AC; Department of General Surgery, Hospital Sultan Ismail Petra, 18000, Kuala Krai, Kelantan, Malaysia., Rahman KA; Department of General Surgery, Hospital Sultan Ismail Petra, 18000, Kuala Krai, Kelantan, Malaysia., Zulkifli ASM; Department of General Surgery, Hospital Sultan Ismail Petra, 18000, Kuala Krai, Kelantan, Malaysia., Petronio B; Chirurgia Generale e Mininvasiva, San Polo Monfalcone, Monfalcone, GO, Italy., Matías-García B; Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain., Quiroga-Valcárcel A; Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain., Mendoza-Moreno F; Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain., Atanasov B; RIMU, Medical University of Plovdiv, UMHAT Eurohospital, Plovdiv, Bulgaria., Campanile FC; Ospedale San Giovanni Decollato Andosilla - ASL, Civita Castellana, Viterbo, VT, Italy., Vecchioni I; Ospedale San Giovanni Decollato Andosilla - ASL, Civita Castellana, Viterbo, VT, Italy., Cardinali L; UOC Chirurgia Generale, Ospedale 'Madonna del Soccorso', San Benedetto del Tronto, AP, Italy., Travaglini G; UOC Chirurgia Generale, Ospedale 'Madonna del Soccorso', San Benedetto del Tronto, AP, Italy., Sebastiani E; UOC Chirurgia Generale, Ospedale 'Madonna del Soccorso', San Benedetto del Tronto, AP, Italy., Chooklin S; Lviv Regional Clinical Hospital, Lviv, Ukraine., Chuklin S; Lviv Regional Clinical Hospital, Lviv, Ukraine., Cianci P; Lorenzo Bonomo Hospital, ASL BAT, Andria, Puglia, Italy., Restini E; Lorenzo Bonomo Hospital, ASL BAT, Andria, Puglia, Italy., Capuzzolo S; Lorenzo Bonomo Hospital, ASL BAT, Andria, Puglia, Italy., Currò G; Generall Surgery Unit, Science of Health Department, 'Mater Domini' Hospital, University 'Magna Graecia' Medical School, Viale Europa, 88100, Germaneto, Catanzaro, Italy., Filippo R; Generall Surgery Unit, Science of Health Department, 'Mater Domini' Hospital, University 'Magna Graecia' Medical School, Viale Europa, 88100, Germaneto, Catanzaro, Italy., Rispoli M; Generall Surgery Unit, Science of Health Department, 'Mater Domini' Hospital, University 'Magna Graecia' Medical School, Viale Europa, 88100, Germaneto, Catanzaro, Italy., Aparicio-Sánchez D; Emergency Surgery Unit, Hospital Virgen del Rocío, Seville, Spain., Muñóz-Cruzado VD; Emergency Surgery Unit, Hospital Virgen del Rocío, Seville, Spain., Barbeito SD; Emergency Surgery Unit, Hospital Virgen del Rocío, Seville, Spain., Delibegovic S; Clinic for Surgery, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina., Kesetovic A; Clinic for Surgery, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina., Sasia D; Santa Croce and Carle Hospital, Cuneo, Italy., Borghi F; Santa Croce and Carle Hospital, Cuneo, Italy., Giraudo G; Santa Croce and Carle Hospital, Cuneo, Italy., Visconti D; Chirurgia Generale d'Urgenza e PS - AOU Cittá della Salute e della Scienza, Turin, Italy., Doria E; Chirurgia Generale d'Urgenza e PS - AOU Cittá della Salute e della Scienza, Turin, Italy., Santarelli M; Chirurgia Generale d'Urgenza e PS - AOU Cittá della Salute e della Scienza, Turin, Italy., Luppi D; General and Emergency Surgery, ASMN IRCCS REGGIO EMILIA, Reggio Emilia, Italy., Bonilauri S; General and Emergency Surgery, ASMN IRCCS REGGIO EMILIA, Reggio Emilia, Italy., Grossi U; Surgery Unit 2, Regional Hospital Treviso, DISCOG, University of Padua, Treviso, Italy., Zanus G; Surgery Unit 2, Regional Hospital Treviso, DISCOG, University of Padua, Treviso, Italy., Sartori A; U.O. Chirurgia Generale e d'Urgenza Ospedale San Valentino, Montebelluna, Treviso, Italy., Piatto G; U.O. Chirurgia Generale e d'Urgenza Ospedale San Valentino, Montebelluna, Treviso, Italy., De Luca M; U.O. Chirurgia Generale e d'Urgenza Ospedale San Valentino, Montebelluna, Treviso, Italy., Vita D; Surgery Unit 2, Regional Hospital Treviso, DISCOG, University of Padua, Treviso, Italy., Conti L; Department of Surgery, G. Da Saliceto Hospital, AUSL Piacenza, Piacenza, Italy., Capelli P; Department of Surgery, G. Da Saliceto Hospital, AUSL Piacenza, Piacenza, Italy., Cattaneo GM; Department of Surgery, G. Da Saliceto Hospital, AUSL Piacenza, Piacenza, Italy., Marinis A; Styliani-Aikaterini Vederaki, Third Department of Surgery, 'Tzaneio' General Hospital, Piraeus, Greece., Vederaki SA; Styliani-Aikaterini Vederaki, Third Department of Surgery, 'Tzaneio' General Hospital, Piraeus, Greece., Bayrak M; Mehmet Bayrak, Clinic for Surgery, Private Ortadogu Hospital, Adana, Turkey., Altıntas Y; Clinic for Radiology, Private Medline Hospital, Adana, Turkey., Uzunoglu MY; Department of General Surgery, Kestel State Hospital, Bursa, Turkey., Demirbas IE; Department of General Surgery, Kestel State Hospital, Bursa, Turkey., Altinel Y; Department of General Surgery, Bagcilar Training and Research Hospital, University of Health Science, Istanbul, Turkey., Meric S; Department of General Surgery, Bagcilar Training and Research Hospital, University of Health Science, Istanbul, Turkey., Aktimur YE; Department of General Surgery, Bagcilar Training and Research Hospital, University of Health Science, Istanbul, Turkey., Uymaz DS; General Surgery Department, Faculty of Medicine, Koc University, Istanbul, Turkey., Omarov N; General Surgery Department, Faculty of Medicine, Koc University, Istanbul, Turkey., Azamat I; General Surgery Department, Faculty of Medicine, Koc University, Istanbul, Turkey., Lostoridis E; 1St Department of Surgery, Kavala General Hospital, Kavala, Greece., Nagorni EA; 1St Department of Surgery, Kavala General Hospital, Kavala, Greece., Pujante A; 1St Department of Surgery, Kavala General Hospital, Kavala, Greece., Anania G; UO Chirurgia 1, Dipartimento Chirurgico, Arcispedale Sant'Anna, Azienda Ospedaliero-Universitaria'di Ferrara, Ferrara, Italy., Bombardini C; UO Chirurgia 1, Dipartimento Chirurgico, Arcispedale Sant'Anna, Azienda Ospedaliero-Universitaria'di Ferrara, Ferrara, Italy., Bagolini F; UO Chirurgia 1, Dipartimento Chirurgico, Arcispedale Sant'Anna, Azienda Ospedaliero-Universitaria'di Ferrara, Ferrara, Italy., Gonullu E; Sakarya Training and Research Hospital, Sakarya, Turkey., Mantoglu B; Sakarya Training and Research Hospital, Sakarya, Turkey., Capoglu R; Sakarya Training and Research Hospital, Sakarya, Turkey., Cappato S; Department of General Surgery ASL 4, Lavagna Hospital, Genoa, Italy., Muzio E; Department of General Surgery ASL 4, Lavagna Hospital, Genoa, Italy., Colak E; Samsun Training and Research Hospital, University of Samsun, Samsun, Turkey., Polat S; Samsun Training and Research Hospital, University of Samsun, Samsun, Turkey., Koylu ZA; Samsun Training and Research Hospital, University of Samsun, Samsun, Turkey., Altintoprak F; Department of General Surgery, Faculty of Medicine, Sakarya University, Serdivan, Turkey., Bayhan Z; Department of General Surgery, Faculty of Medicine, Sakarya University, Serdivan, Turkey., Akin E; Department of General Surgery, Faculty of Medicine, Sakarya University, Serdivan, Turkey., Andolfi E; General and Emergency Surgery Unit, San Donato Hospital, Arezzo, Italy., Rezart S; General and Emergency Surgery Unit, San Donato Hospital, Arezzo, Italy., Kim JI; Department of Surgery, Inje University Ilsan Paik Hospital, Goyang, South Korea., Jung SW; Department of Surgery, Inje University Ilsan Paik Hospital, Goyang, South Korea., Shin YC; Department of Surgery, Inje University Ilsan Paik Hospital, Goyang, South Korea., Enciu O; Elias University Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Toma EA; Elias University Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Medas F; Department of Surgical Science, University of Cagliari, Cagliari, Italy., Canu GL; Department of Surgical Science, University of Cagliari, Cagliari, Italy., Cappellacci F; Department of Surgical Science, University of Cagliari, Cagliari, Italy., D'Acapito F; General and Oncologic Surgery, Morgagni-Pierantoni Hospital, AUSL Romagna, Via C. Forlanini 34, 47121, Forlì, Italy., Ercolani G; General and Oncologic Surgery, Morgagni-Pierantoni Hospital, AUSL Romagna, Via C. Forlanini 34, 47121, Forlì, Italy., Solaini L; General and Oncologic Surgery, Morgagni-Pierantoni Hospital, AUSL Romagna, Via C. Forlanini 34, 47121, Forlì, Italy., Roscio F; Emergency Surgery, ASST Valle Olona, Busto Arsizio, Italy., Clerici F; Emergency Surgery, ASST Valle Olona, Busto Arsizio, Italy., Gelmini R; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine AOU Policlinico Di Modena, Modena, Italy., Serra F; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine AOU Policlinico Di Modena, Modena, Italy., Rossi EG; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine AOU Policlinico Di Modena, Modena, Italy., Fleres F; UOC General Surgery, Hospital Civil of Sondrio, ASST Valtellina e Alto Lario, Sondrio, Italy., Clarizia G; UOC General Surgery, Hospital Civil of Sondrio, ASST Valtellina e Alto Lario, Sondrio, Italy., Spolini A; UOC General Surgery, Hospital Civil of Sondrio, ASST Valtellina e Alto Lario, Sondrio, Italy., Ferrara F; Department of Surgery, San Carlo Borromeo Hospital, ASST Santi Paolo e Carlo, Milan, Italy., Nita G; AUSL Reggio Emilia, Ospedale Sant'Anna, Castelnuovo ne Monti, Reggio Emilia, Italy., Sarnari J; AUSL Reggio Emilia, Ospedale Sant'Anna, Castelnuovo ne Monti, Reggio Emilia, Italy., Gachabayov M; Department of Abdominal Surgery, Vladimir City Emergency Hospital, Vladimir, Russia., Abdullaev A; Department of Abdominal Surgery, Vladimir City Emergency Hospital, Vladimir, Russia., Poillucci G; Policlinico Universitario Umberto I, Rome, Italy., Palini GM; Chirurgia generale e d'urgenza, Ospedale Infermi di Rimini, AUSL Romagna, Rimini, Italy., Veneroni S; Chirurgia generale e d'urgenza, Ospedale Infermi di Rimini, AUSL Romagna, Rimini, Italy., Garulli G; Chirurgia generale e d'urgenza, Ospedale Infermi di Rimini, AUSL Romagna, Rimini, Italy., Piccoli M; Department of General Surgery, Emergencies and New Technologies, Baggiovara Civil Hospital, Modena, Italy., Pattacini GC; Department of General Surgery, Emergencies and New Technologies, Baggiovara Civil Hospital, Modena, Italy., Pecchini F; Department of General Surgery, Emergencies and New Technologies, Baggiovara Civil Hospital, Modena, Italy., Argenio G; UOC Chirurgia d'Urgenza, AOU San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy., Armellino MF; UOC Chirurgia d'Urgenza, AOU San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy., Brisinda G; Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy., Tedesco S; Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy., Fransvea P; Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy., Ietto G; General, Emergency and Transplant Surgery Department, ASST-Settelaghi and University of Insubria, Varese, Italy., Franchi C; General, Emergency and Transplant Surgery Department, ASST-Settelaghi and University of Insubria, Varese, Italy., Carcano G; General, Emergency and Transplant Surgery Department, ASST-Settelaghi and University of Insubria, Varese, Italy., Martines G; General Surgery Unit, Azienda Ospedaliero Universitaria Policlinico Bari - Italy, Bari, Italy., Trigiante G; General Surgery Unit, Azienda Ospedaliero Universitaria Policlinico Bari - Italy, Bari, Italy., Negro G; General Surgery Unit, Azienda Ospedaliero Universitaria Policlinico Bari - Italy, Bari, Italy., Vega GM; Department of Surgery, Hospital de Clinicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay., González AR; Department of Surgery, Hospital de Clinicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay., Ojeda L; Department of Surgery, Hospital de Clinicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay., Piccolo G; Unit of HepatoBilioPancreatic and Digestive Surgery, Department of Health Sciences, San Paolo Hospital, University of Milan, Via Di Rudinì 8, 20142, Milan, Italy., Bondurri A; Department of General Surgery, Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco University Hospital, Università degli Studi di Milano, Milan, Italy., Maffioli A; Department of General Surgery, Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco University Hospital, Università degli Studi di Milano, Milan, Italy., Guerci C; Department of General Surgery, Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco University Hospital, Università degli Studi di Milano, Milan, Italy., Sin BH; HPB Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, Malaysia., Zuhdi Z; HPB Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, Malaysia., Azman A; HPB Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, Malaysia., Mousa H; College of Medicine, Tawam Hospital, UAE University, Al-Ain, UAE., Al Bahri S; College of Medicine, Tawam Hospital, UAE University, Al-Ain, UAE., Augustin G; Department of Surgery, University Hospital Centre, Zagreb, Croatia., Romic I; Department of Surgery, University Hospital Centre, Zagreb, Croatia., Moric T; Department of Surgery, University Hospital Centre, Zagreb, Croatia., Nikolopoulos I; Lewisham and Greenwich NHS Trust, London, UK., Andreuccetti J; 2nd Department of General Surgery, ASST Spedali Civili of Brescia, Brescia, Italy., Pignata G; 2nd Department of General Surgery, ASST Spedali Civili of Brescia, Brescia, Italy., D'Alessio R; 2nd Department of General Surgery, ASST Spedali Civili of Brescia, Brescia, Italy., Kenig J; Department of General, Gastrointestinal, Oncologic Surgery and Transplantology, Jagiellonian University Medical College, Kraków, Poland., Skorus U; Department of General, Gastrointestinal, Oncologic Surgery and Transplantology, Jagiellonian University Medical College, Kraków, Poland., Fraga GP; Division of Trauma Surgery, School of Medical Sciences, University of Campinas (Unicamp), Campinas, Brazil., Hirano ES; Division of Trauma Surgery, School of Medical Sciences, University of Campinas (Unicamp), Campinas, Brazil., de Lima Bertuol JV; Division of General Surgery, Western Paraná University Hospital (Huop-Unioeste), Cascavel, Brazil., Isik A; School of Medicine, Erzincan University, Erzincan, Turkey., Kurnaz E; School of Medicine, Erzincan University, Erzincan, Turkey., Asghar MS; King Edward Medical University, Lahore, Pakistan., Afzal A; King Edward Medical University, Lahore, Pakistan., Akbar A; King Edward Medical University, Lahore, Pakistan., Nikolouzakis TK; Department of General Surgery, University General Hospital of Heraklion, 71110, Heraklion, Crete, Greece., Lasithiotakis K; Department of General Surgery, University General Hospital of Heraklion, 71110, Heraklion, Crete, Greece., Chrysos E; Department of General Surgery, University General Hospital of Heraklion, 71110, Heraklion, Crete, Greece., Das K; Department of General Surgery, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey., Özer N; Department of General Surgery, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey., Seker A; Department of General Surgery, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey., Ibrahim M; Kuwaiti Specialized Hospital, Khartoum, Sudan., Hamid HKS; Kuwaiti Specialized Hospital, Khartoum, Sudan., Babiker A; Kuwaiti Specialized Hospital, Khartoum, Sudan., Bouliaris K; Surgical Department, Koutlimbaneio and Triantafylleio General Hospital of Larissa, Larisa, Greece., Koukoulis G; Surgical Department, Koutlimbaneio and Triantafylleio General Hospital of Larissa, Larisa, Greece., Kolla CC; Surgical Department, Koutlimbaneio and Triantafylleio General Hospital of Larissa, Larisa, Greece., Lucchi A; U.O. Chirurgia Generale Ospedale 'Ceccarini' Riccione, Riccione, Italy., Agostinelli L; U.O. Chirurgia Generale Ospedale 'Ceccarini' Riccione, Riccione, Italy., Taddei A; Hepatobiliary Surgery, Department of Clinical and Experimental Medicine, University of Florence, AOU Careggi, Florence, Italy., Fortuna L; Hepatobiliary Surgery, Department of Clinical and Experimental Medicine, University of Florence, AOU Careggi, Florence, Italy., Agostini C; Hepatobiliary Surgery, Department of Clinical and Experimental Medicine, University of Florence, AOU Careggi, Florence, Italy., Licari L; Department of Surgical, Oncological and Oral Sciences (DICHIRONS), Policlinico P. Giaccone, University of Palermo, Via Liborio Giuffré 5, 90127, Palermo, Italy., Viola S; University of Palermo, Palermo, Italy., Callari C; Department of Surgery, Buccheri La Ferla Hospital, Via Messina Marine, 197, 90123, Palermo, Italy., Laface L; Department of General Surgery, Vittorio Emanuele III Hospital, Carate Brianza - ASST Brianza, Carate Brianza, Italy., Abate E; Department of General Surgery, Vittorio Emanuele III Hospital, Carate Brianza - ASST Brianza, Carate Brianza, Italy., Casati M; Department of General Surgery, Vittorio Emanuele III Hospital, Carate Brianza - ASST Brianza, Carate Brianza, Italy., Anastasi A; Chirurgia Generale, Ospedale San Giovanni Di Dio, Florence, Italy., Canonico G; Chirurgia Generale, Ospedale San Giovanni Di Dio, Florence, Italy., Gabellini L; Chirurgia Generale, Ospedale San Giovanni Di Dio, Florence, Italy., Tosi L; Residency Program in General Surgery, University of Bologna, Bologna, Italy., Guariniello A; Section of Emergency Surgery, Department of Surgery, S.Maria delle Croci Hospital Ravenna, Ravenna, Italy., Zanzi F; Section of Emergency Surgery, Department of Surgery, S.Maria delle Croci Hospital Ravenna, Ravenna, Italy., Bains L; Department of Surgery, Maulana Azad Medical College and Nayak Hospital, New Delhi, 110002, India., Sydorchuk L; Bukovinian State Medical University, Chernivtsi, Ukraine., Iftoda O; Bukovinian State Medical University, Chernivtsi, Ukraine., Sydorchuk A; Bukovinian State Medical University, Chernivtsi, Ukraine., Malerba M; Ospedale Santa Corona, ASL 2, Savona, Italy., Costanzo F; Ospedale Santa Corona, ASL 2, Savona, Italy., Galleano R; Ospedale Santa Corona, ASL 2, Savona, Italy., Monteleone M; Andrea Costanzi, Carlo Riva, O.U. of General Surgery, San Leopoldo Mandic Hospital, Merate, ASST, Lecco, Italy., Costanzi A; Andrea Costanzi, Carlo Riva, O.U. of General Surgery, San Leopoldo Mandic Hospital, Merate, ASST, Lecco, Italy., Riva C; Andrea Costanzi, Carlo Riva, O.U. of General Surgery, San Leopoldo Mandic Hospital, Merate, ASST, Lecco, Italy., Walędziak M; Department of General, Oncological, Metabolic and Thoracic Surgery, Military Institute of Medicine, Warsaw, Poland., Kwiatkowski A; Department of General, Oncological, Metabolic and Thoracic Surgery, Military Institute of Medicine, Warsaw, Poland., Czyżykowski Ł; Department of General, Oncological, Metabolic and Thoracic Surgery, Military Institute of Medicine, Warsaw, Poland., Major P; Department of General and Emergency Surgery, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland., Strzałka M; Department of General and Emergency Surgery, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland., Matyja M; Department of General and Emergency Surgery, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland., Natkaniec M; Department of General and Emergency Surgery, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland., Valenti MR; U.O. General Surgery, Azienda Ospedaliera Universitaria 'Policlinico - San Marco', Catania, Italy., Di Vita MDP; U.O. General Surgery, Azienda Ospedaliera Universitaria 'Policlinico - San Marco', Catania, Italy., Sotiropoulou M; 3Rd Surgical Department, Evangelismos General Hospital, Athens, Greece., Kapiris S; 3Rd Surgical Department, Evangelismos General Hospital, Athens, Greece., Massalou D; Department of Emergency Surgery, Centre Hospitalier Universitaire de Nice (CHU de Nice), Université Côte d'Azur, Nice, France., Veroux M; General Surgery, Azienda Policlinico San Marco, Catania, Italy., Volpicelli A; General Surgery, Azienda Policlinico San Marco, Catania, Italy., Gioco R; General Surgery, Azienda Policlinico San Marco, Catania, Italy., Uccelli M; General and Oncological Surgery Department, San Marco Hospital GSD, Zingonia, BG, Italy., Bonaldi M; General and Oncological Surgery Department, San Marco Hospital GSD, Zingonia, BG, Italy., Olmi S; General and Oncological Surgery Department, San Marco Hospital GSD, Zingonia, BG, Italy., Nardi M; San Giovanni Calibita Hospital- Fondazione Fatebenefratelli, Rome, Italy., Livadoti G; San Giovanni Calibita Hospital- Fondazione Fatebenefratelli, Rome, Italy., Mesina C; Department of Surgery, Emergency County Hospital of Craiova, Craiova, Romania., Dumitrescu TV; Department of Surgery, Emergency County Hospital of Craiova, Craiova, Romania., Ciorbagiu MC; Department of Surgery, Emergency County Hospital of Craiova, Craiova, Romania., Ammendola M; Science of Health Department, Digestive Surgery Unit, 'Mater Domini' Hospital, University 'Magna Graecia' Medical School, Viale Europa, 88100, Germaneto, Catanzaro, Italy., Ammerata G; Science of Health Department, Digestive Surgery Unit, 'Mater Domini' Hospital, University 'Magna Graecia' Medical School, Viale Europa, 88100, Germaneto, Catanzaro, Italy., Romano R; Science of Health Department, Digestive Surgery Unit, 'Mater Domini' Hospital, University 'Magna Graecia' Medical School, Viale Europa, 88100, Germaneto, Catanzaro, Italy., Slavchev M; Department of General Surgery, University Hospital Eurohospital, Plovdiv, Bulgaria., Misiakos EP; 3Rd Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Pikoulis E; 3Rd Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Papaconstantinou D; 3Rd Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Elbahnasawy M; Emergency Medicine and Traumatology Department, Tanta University Faculty of Medicine, Tanta, Egypt., Abdel-Elsalam S; Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University, Tanta, Egypt., Felsenreich DM; Division of Visceral Surgery, Department of General Surgery, Medical University of Vienna, Vienna, Austria., Jedamzik J; Division of Visceral Surgery, Department of General Surgery, Medical University of Vienna, Vienna, Austria., Michalopoulos NV; 4Rd Department of Surgery Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Sidiropoulos TA; 4Rd Department of Surgery Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Papadoliopoulou M; 4Rd Department of Surgery Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Cillara N; Surgery Department, Santissima Trinità Hospital, Cagliari, Italy., Deserra A; Surgery Department, Santissima Trinità Hospital, Cagliari, Italy., Cannavera A; Surgery Department, Santissima Trinità Hospital, Cagliari, Italy., Negoi I; General Surgery Department, Carol Davila University of Medicine and Pharmacy, Emergency Hospital of Bucharest, Bucharest, Romania., Schizas D; First Department of Surgery, National and Kapodistrian University of Athens, Laiko General Hospital, 11527, Athens, Greece., Syllaios A; First Department of Surgery, National and Kapodistrian University of Athens, Laiko General Hospital, 11527, Athens, Greece., Vagios I; First Department of Surgery, National and Kapodistrian University of Athens, Laiko General Hospital, 11527, Athens, Greece., Gourgiotis S; Addenbrooke's Hospital, Cambridge University, Cambridge, UK., Dai N; Addenbrooke's Hospital, Cambridge University, Cambridge, UK., Gurung R; Addenbrooke's Hospital, Cambridge University, Cambridge, UK., Norrey M; Addenbrooke's Hospital, Cambridge University, Cambridge, UK., Pesce A; Department of Surgery, Delta Hospital, Azienda USL of Ferrara, University of Ferrara, Ferrara, Italy., Feo CV; Department of Surgery, Delta Hospital, Azienda USL of Ferrara, University of Ferrara, Ferrara, Italy., Fabbri N; Department of Surgery, Delta Hospital, Azienda USL of Ferrara, University of Ferrara, Ferrara, Italy., Machairas N; 2Nd Department of Propaedeutic Surgery, National and Kapodistrian University of Athens, General Hospital Laiko, Athens, Greece., Dorovinis P; 2Nd Department of Propaedeutic Surgery, National and Kapodistrian University of Athens, General Hospital Laiko, Athens, Greece., Keramida MD; 2Nd Department of Propaedeutic Surgery, National and Kapodistrian University of Athens, General Hospital Laiko, Athens, Greece., Mulita F; Department of Surgery, General University Hospital of Patras, Patras, Greece., Verras GI; Department of Surgery, General University Hospital of Patras, Patras, Greece., Vailas M; Department of Surgery, General University Hospital of Patras, Patras, Greece., Yalkin O; Department of Surgical Oncology and Gastroenterological Surgery, Bursa City Hospital, Bursa, Turkey., Iflazoglu N; Department of Surgical Oncology and Gastroenterological Surgery, Bursa City Hospital, Bursa, Turkey., Yigit D; Department of Surgical Oncology and Gastroenterological Surgery, Bursa City Hospital, Bursa, Turkey., Baraket O; Department of General Surgery, Habib Bougatfa Hospital, University Tunis El Manar, Bizerte, Tunisia., Ayed K; Department of General Surgery, Habib Bougatfa Hospital, University Tunis El Manar, Bizerte, Tunisia., Ghalloussi MH; Department of General Surgery, Habib Bougatfa Hospital, University Tunis El Manar, Bizerte, Tunisia., Patias P; 2nd Department of Surgery, General Hospital of Athens 'G.Gennimatas', Athens, Greece., Ntokos G; 2nd Department of Surgery, General Hospital of Athens 'G.Gennimatas', Athens, Greece., Rahim R; Department of Surgery, Universiti Sains Islam Malaysia, Nilai, Malaysia., Bala M; Department of General Surgery and Trauma, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Kedar A; Department of General Surgery and Trauma, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Sawyer RG; Western Michigan University School of Medicine, Kalamazoo, USA., Trinh A; Western Michigan University School of Medicine, Kalamazoo, USA., Miller K; Western Michigan University School of Medicine, Kalamazoo, USA., Sydorchuk R; Regional Emergency Hospital, Chernivtsi, Ukraine., Knut R; Regional Emergency Hospital, Chernivtsi, Ukraine., Plehutsa O; Regional Emergency Hospital, Chernivtsi, Ukraine., Liman RK; General Surgery Clinic, Elazig Fethi Sekin City Hospital, Elazig, Turkey., Ozkan Z; General Surgery Clinic, Elazig Fethi Sekin City Hospital, Elazig, Turkey., Kader SA; Egypt and NMC Specialty Hospital Al Ain, Ain Shams University, Al-Ain, UAE., Gupta S; Government Medical College and Hospital, Chandigarh, India., Gureh M; Government Medical College and Hospital, Chandigarh, India., Saeidi S; Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Aliakbarian M; Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Dalili A; Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Shoko T; Department of Emergency and Critical Care Medicine, Department of Acute Care Surgery Center, Adachi Medical Center, Tokyo Women's Medical University, Tokyo, Japan., Kojima M; Department of Emergency and Critical Care Medicine, Department of Acute Care Surgery Center, Adachi Medical Center, Tokyo Women's Medical University, Tokyo, Japan., Nakamoto R; Department of Emergency and Critical Care Medicine, Department of Acute Care Surgery Center, Adachi Medical Center, Tokyo Women's Medical University, Tokyo, Japan., Atici SD; Department of General Surgery, University of Health Sciences Tepecik Training and Research Hospital, Izmir, Turkey., Tuncer GK; Department of General Surgery, University of Health Sciences Tepecik Training and Research Hospital, Izmir, Turkey., Kaya T; Department of General Surgery, University of Health Sciences Tepecik Training and Research Hospital, Izmir, Turkey., Delis SG; HPB Unit Konstantopouleio Hospital St Olga, Athens, Greece., Rossi S; Department of General and Emergency Surgery, San Filippo Neri Hospital, ASL Roma 1, Rome, Italy., Picardi B; Department of General and Emergency Surgery, San Filippo Neri Hospital, ASL Roma 1, Rome, Italy., Del Monte SR; Department of General and Emergency Surgery, San Filippo Neri Hospital, ASL Roma 1, Rome, Italy., Triantafyllou T; Department of Surgery, Hippocration General Hospital of Athens, University of Athens, Athens, Greece., Theodorou D; Department of Surgery, Hippocration General Hospital of Athens, University of Athens, Athens, Greece., Pintar T; Department of Abdominal Surgery, University Medical Center Ljubljana, Ljubljana, Slovenia., Salobir J; Department of Abdominal Surgery, University Medical Center Ljubljana, Ljubljana, Slovenia., Manatakis DK; Vasileios Acheimastos, Athens Naval and Veterans Hospital, Athens, Greece., Tasis N; Vasileios Acheimastos, Athens Naval and Veterans Hospital, Athens, Greece., Acheimastos V; Vasileios Acheimastos, Athens Naval and Veterans Hospital, Athens, Greece., Ioannidis O; 4Th Department of Surgery, Medical School Aristotle University of Thessaloniki, General Hospital 'George Papanikolaou', Thessaloniki, Greece., Loutzidou L; 4Th Department of Surgery, Medical School Aristotle University of Thessaloniki, General Hospital 'George Papanikolaou', Thessaloniki, Greece., Symeonidis S; 4Th Department of Surgery, Medical School Aristotle University of Thessaloniki, General Hospital 'George Papanikolaou', Thessaloniki, Greece., de Sá TC; General Surgery Department, Centro Hospitalar Do Tâmega e Sousa Penafiel, Penafiel, Portugal., Rocha M; General Surgery Department, Centro Hospitalar Do Tâmega e Sousa Penafiel, Penafiel, Portugal., Guagni T; Department of general surgery, Careggi University Hospital, Florence, Italy., Pantalone D; Department of general surgery, Careggi University Hospital, Florence, Italy., Maltinti G; Department of general surgery, Careggi University Hospital, Florence, Italy., Khokha V; Emergency Surgery Department, City Hospital, Mozyr, Belarus., Abdel-Elsalam W; Anesthesia and Surgical Intensive Care Department, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt., Ghoneim B; Anesthesia and Surgical Intensive Care Department, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt., López-Ruiz JA; Angeles Gil-Olarte, Estela Romero-Vargas, Hospital Universitario Virgen Macarena, Seville, Spain., Kara Y; General Surgery Clinic Health Sciences University Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey., Zainudin S; Faculty of Medicine and Health Sciences, Queen Elisabeth Hospital, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia., Hayati F; Faculty of Medicine and Health Sciences, Queen Elisabeth Hospital, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia., Azizan N; Faculty of Medicine and Health Sciences, Queen Elisabeth Hospital, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia., Khei VTP; Department of Surgery, Queen Elizabeth Hospital, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia., Yi RCX; Department of Surgery, Queen Elizabeth Hospital, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia., Sellappan H; Department of Surgery, Queen Elizabeth Hospital, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia., Demetrashvili Z; N.Kipshidze Central University Hospital, Tbilisi, Georgia., Lekiashvili N; N.Kipshidze Central University Hospital, Tbilisi, Georgia., Tvaladze A; N.Kipshidze Central University Hospital, Tbilisi, Georgia., Froiio C; IRCCS Policlinico San Donato, University of Milan, Milan, Italy., Bernardi D; IRCCS Policlinico San Donato, University of Milan, Milan, Italy., Bonavina L; IRCCS Policlinico San Donato, University of Milan, Milan, Italy., Gil-Olarte A; Angeles Gil-Olarte, Estela Romero-Vargas, Hospital Universitario Virgen Macarena, Seville, Spain., Grassia S; General Surgery Unit, S. Leonardo Hospital, Castellammare Di Stabia, Naples, Italy., Romero-Vargas E; Angeles Gil-Olarte, Estela Romero-Vargas, Hospital Universitario Virgen Macarena, Seville, Spain., Bianco F; General Surgery Unit, S. Leonardo Hospital, Castellammare Di Stabia, Naples, Italy., Gumbs AA; Department of Emergency, Digestive and Metabolic Minimally Invasive Surgery, Poissy and Saint Germain en Laye Hospitals, Poissy, France., Dogjani A; Department of General Surgery, University Hospital of Tirana, Tirana, Albania., Agresta F; Department of General Surgery, AULSS2 Trevigiana del Veneto, Ospedale di Vittorio Veneto, Vittorio Veneto, TV, Italy., Litvin A; Department of Surgical Disciplines, Immanuel Kant Baltic Federal University, Regional Clinical Hospital, Kalingrad, Russia., Balogh ZJ; Department of Traumatology, John Hunter Hospital and University of Newcastle, Newcastle, NSW, Australia., Gendrikson G; Department of Surgical Disciplines, Immanuel Kant Baltic Federal University, Regional Clinical Hospital, Kalingrad, Russia., Martino C; Anesthesia and Intensive Care Unit, Umberto I Hospital, AUSL Romagna, Lugo, Italy., Damaskos D; Department of General and Emergency Surgery, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, UK., Pararas N; Department of General Surgery, Dr. Sulaiman Al Habib Hospital, Alfaisal University, Riyadh, Saudi Arabia., Kirkpatrick A; General, Acute Care, Abdominal Wall Reconstruction, and Trauma Surgery, Foothills Medical Centre, Calgary, AB, Canada., Kurtenkov M; Department of Surgical Disciplines, Immanuel Kant Baltic Federal University, Regional Clinical Hospital, Kalingrad, Russia., Gomes FC; Faculdade de Ciência Médicas e da Saúde de Juiz de Fora, Hospital Universitario Terezinha de Jesus (SUPREMA), Juiz de Fora, Brazil., Pisanu A; Department of Surgical Science, University of Cagliari, Cagliari, Italy., Nardello O; Department of Surgical Science, University of Cagliari, Cagliari, Italy., Gambarini F; Hospital 'Istituto Città di Pavia', Pavia, Italy., Aref H; Department of Emergency, Digestive and Metabolic Minimally Invasive Surgery, Poissy and Saint Germain en Laye Hospitals, Poissy, France., Angelis ND; Unit of Digestive and HPB Surgery, CARE Department, Henri Mondor Hospital and University Paris-Est, Creteil, France., Agnoletti V; Department of General and Trauma Surgery, Bufalini Hospital, Cesena, Italy., Biondi A; Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy., Vacante M; Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy., Griggio G; Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy., Tutino R; Chirurgia 1; Dipartimento di Discipline Chirurgiche , Oncologiche e Stomatologiche (DI.CHIR.ON.S), Ospedale 'Ca'Foncell'; Univerità degli studi di Palermo, Treviso; Palermo, Italy., Massani M; Chirurgia 1; Dipartimento di Discipline Chirurgiche , Oncologiche e Stomatologiche (DI.CHIR.ON.S), Ospedale 'Ca'Foncell'; Univerità degli studi di Palermo, Treviso; Palermo, Italy., Bisetto G; Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologica (DI.SC.O.G.), Chirurgia 1-Ospedale 'Ca Foncello'- Treviso, Università degli Studi di Padova, Padua, Italy., Occhionorelli S; Department of General Surgery, Arcispedale Sant'Anna-University of Ferrara, Ferrara, Italy., Andreotti D; Department of General Surgery, Arcispedale Sant'Anna-University of Ferrara, Ferrara, Italy., Lacavalla D; Department of General Surgery, Arcispedale Sant'Anna-University of Ferrara, Ferrara, Italy., Biffl WL; Department of Emergency and Trauma Surgery, Scripps Clinic Medical Group, La Jolla, CA, USA., Catena F; Department of General and Trauma Surgery, Bufalini Hospital, Cesena, Italy.

Publikováno v: World journal of emergency surgery : WJES [World J Emerg Surg] 2022 Dec 16; Vol. 17 (1), pp. 61. Date of Electronic Publication: 2022 Dec 16.

Implementation of video-calls between patients admitted to intensive care unit during the COVID-19 pandemic and their families: a pilot study of psychological effects.

Autor: Sanfilippo F; Department of Anaesthesia and Intensive Care, A.O.U. 'Policlinico-San Marco', Catania, Italy. filipposanfi@yahoo.it., La Via L; Department of Anaesthesia and Intensive Care, A.O.U. 'Policlinico-San Marco', Catania, Italy., Schembari G; School of Anaesthesia and Intensive Care, University 'Magna Graecia', Catanzaro, Italy., Tornitore F; School of Anaesthesia and Intensive Care, University 'Magna Graecia', Catanzaro, Italy., Zuccaro G; School of Anaesthesia and Intensive Care, University 'Magna Graecia', Catanzaro, Italy., Morgana A; School of Anaesthesia and Intensive Care, University 'Magna Graecia', Catanzaro, Italy., Valenti MR; Department of Anaesthesia and Intensive Care, A.O.U. 'Policlinico-San Marco', Catania, Italy., Oliveri F; Department of Anaesthesia and Intensive Care, A.O.U. 'Policlinico-San Marco', Catania, Italy., Pappalardo F; Cardiothoracic and Vascular Anesthesia and Intensive Care, AO SS Antonio E Biagio E Cesare Arrigo, Alessandria, Italy., Astuto M; Department of Anaesthesia and Intensive Care, A.O.U. 'Policlinico-San Marco', Catania, Italy.

Publikováno v: Journal of anesthesia, analgesia and critical care [J Anesth Analg Crit Care] 2022 Aug 23; Vol. 2 (1), pp. 38. Date of Electronic Publication: 2022 Aug 23.

OXIDATIVE study: A pilot prospective observational cohort study protocol examining the influence of peri-reperfusion hyperoxemia and immune dysregulation on early allograft dysfunction after orthotopic liver transplantation.

Autor: Wilson, Elizabeth A.¹ (AUTHOR) ewilso5@gmail.com, Woodbury, Anna¹ (AUTHOR), Williams, Kirsten M.² (AUTHOR), Coopersmith, Craig M.³ (AUTHOR)

Publikováno v: PLoS ONE. 3/28/2024, Vol. 19 Issue 3, p1-18. 18p.

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eµ-MYC driven B-cell lymphoma.

Autor: Walton MI; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Eve PD; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Hayes A; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Henley AT; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Valenti MR; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., De Haven Brandon AK; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Box G; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Boxall KJ; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Tall M; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Swales K; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Matthews TP; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., McHardy T; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Lainchbury M; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Osborne J; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Hunter JE; Institute for Cell and Molecular Biosciences, Medical School, Newcastle University, Newcastle Upon Tyne, UK., Perkins ND; Institute for Cell and Molecular Biosciences, Medical School, Newcastle University, Newcastle Upon Tyne, UK., Aherne GW; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Reader JC; Sareum Ltd, Cambridge, UK., Raynaud FI; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Eccles SA; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Collins I; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Garrett MD; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK.; School of Biosciences, University of Kent, Canterbury, Kent, UK.

Publikováno v: Oncotarget [Oncotarget] 2016 Jan 19; Vol. 7 (3), pp. 2329-42.

Discovery of 3-alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-carbonitriles as selective, orally bioavailable CHK1 inhibitors.

Autor: Lainchbury M; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, 15 Cotswold Road, Sutton, SM2 5NG U. K., Matthews TP, McHardy T, Boxall KJ, Walton MI, Eve PD, Hayes A, Valenti MR, de Haven Brandon AK, Box G, Aherne GW, Reader JC, Raynaud FI, Eccles SA, Garrett MD, Collins I

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2012 Nov 26; Vol. 55 (22), pp. 10229-40. Date of Electronic Publication: 2012 Oct 19.