Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Valen Zhuoyou Yu"'
Autor:
Lvwen Ning, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Candy King-Chi Chan, Lihua Tao, Shiu-Yeung Lam, Merrin Man-Long Leong, Roger Kai-Cheong Ngan, Dora Lai-Wan Kwong, Anne Wing-Mui Lee, Wai-Tong Ng, Ashley Cheng, Stewart Tung, Victor Ho-Fun Lee, Ka-On Lam, Chung-Kong Kwan, Wing-Sum Li, Stephen Yau, Jin-Xin Bei, Maria Li Lung
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Here the authors report a major histocompatibility complex (MHC) association analysis for nasopharyngeal carcinoma in Chinese individuals from Hong Kong, finding 8 independent associated loci associated with lower risk for developing nasopharyngeal c
Externí odkaz:
https://doaj.org/article/f82cb968f4d947bb91dd4a6ed21c1e75
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100982- (2021)
Purpose: TP53, encoding the protein p53, is among the most frequently mutated genes in all cancers. A high frequency of 60 – 90% mutations is seen in esophageal squamous cell carcinoma (ESCC) patients. Certain p53 mutants show gain-of-function (GoF
Externí odkaz:
https://doaj.org/article/157a71c317d1415f9ce5518e3d9bfe27
Autor:
Hoi Yan Ng, Jian Li, Lihua Tao, Alfred King-Yin Lam, Kwok Wah Chan, Josephine Mun Yee Ko, Valen Zhuoyou Yu, Michael Wong, Benjamin Li, Maria Li Lung
Publikováno v:
Translational Oncology, Vol 11, Iss 6, Pp 1323-1333 (2018)
The current study reveals the clinicopathological association of PD-L1 in Hong Kong esophageal squamous cell carcinoma (ESCC) patients and the differential regulation of PD-L1 by standard first-line chemotherapy in ESCC. Immunohistochemical analysis
Externí odkaz:
https://doaj.org/article/60c08ecbb8194d0bbaeb0b288b853ad2
Autor:
Maria Li Lung, Josephine Mun-Yee Ko, Candy King-Chi Chan, Merrin Man-Long Leong, Lisa Chan Lei, Valen Zhuoyou Yu, Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Wei Dai
Purpose:Investigation of biological mechanisms underlying genetic alterations in cancer can assist the understanding of etiology and identify the potential prognostic biomarkers.Experimental Design:We performed an integrative genomic analysis for a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854cd4a5cb32a8539f5b4cb7f03b1767
https://doi.org/10.1158/1078-0432.c.6529601
https://doi.org/10.1158/1078-0432.c.6529601
Autor:
Maria Li Lung, Josephine Mun-Yee Ko, Candy King-Chi Chan, Merrin Man-Long Leong, Lisa Chan Lei, Valen Zhuoyou Yu, Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Wei Dai
Figure S5: Methylation of selected genes between NPC and adjacent non-tumor tissues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0111c0b88816fe22b7db067acf0a89d7
https://doi.org/10.1158/1078-0432.22477226
https://doi.org/10.1158/1078-0432.22477226
Autor:
Maria Li Lung, Josephine Mun-Yee Ko, Candy King-Chi Chan, Merrin Man-Long Leong, Lisa Chan Lei, Valen Zhuoyou Yu, Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Wei Dai
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772fbb15cd608c09857e2004815ad20c
https://doi.org/10.1158/1078-0432.22477217.v1
https://doi.org/10.1158/1078-0432.22477217.v1
Autor:
Maria Li Lung, Josephine Mun-Yee Ko, Candy King-Chi Chan, Merrin Man-Long Leong, Lisa Chan Lei, Valen Zhuoyou Yu, Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Wei Dai
Table S1: Clinical parameters for the HK-3 cohort for targeted sequencing (N=402);Table S2: Sample size estimation and power calculation for study cohorts;Table S3: Mutational signatures and clinical parameters in primary NPC (N=178);Table S4: All th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3472c73172f274d23c954c649dd3871
https://doi.org/10.1158/1078-0432.22477214
https://doi.org/10.1158/1078-0432.22477214
Autor:
Valen Zhuoyou Yu, Bryan Chee-chad Lung, Ian Yu-hong Wong, Claudia Lai-yin Wong, Desmond Kwan-kit Chan, Fion Siu-yin Chan, Betty Tsz-ting Law, Simon Law, Maria Li Lung
Publikováno v:
Diseases of the Esophagus. 35
Patient-derived xenografts have been gold standards for cancer modeling and drug testing. However, low establishment efficiency and high maintenance cost have hindered the development in the field. Recently, patient-derived tumor organoid (PDO) cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ae9f669cff9d7b16e9db0483828561
https://doi.org/10.1093/dote/doac051.269
https://doi.org/10.1093/dote/doac051.269
Autor:
Valen Zhuoyou Yu, Shan Shan So, Bryan Chee-Chad Lung, Carissa Wing-Yan Wong, Ian Yu-Hong Wong, Claudia Lai-Yin Wong, Desmond Kwan-Kit Chan, Fion Siu-Yin Chan, Betty Tsz-Ting Law, Ka-On Lam, Anthony Wing-Ip Lo, Josephine Mum-Yee Ko, Wei Dai, Alfred King-Yin Lam, Dora Lai-Wan Kwong, Simon Law, Maria Li Lung
Publikováno v:
Cancer Research. 83:2611-2611
Background: Esophageal squamous cell carcinoma (ESCC) is the predominant form of esophageal cancer in developing areas and is among the top 10 deadliest cancers with a dismal 5-year survival rate of 10~20%. ESCC molecular pathogenesis has not been we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2af665b42ec0dac0e6cd6c50fbb86d37
https://doi.org/10.1158/1538-7445.am2023-2611
https://doi.org/10.1158/1538-7445.am2023-2611
Autor:
Bryan Chee-chad Lung, Valen Zhuoyou Yu, Ian Yu-hong Wong, Claudia Lai-yin Wong, Desmond Kwan-kit Chan, Fion Siu-yin Chan, Betty Tsz-ting Law, Ka-on Lam, Dora Lai-wan Kwong, Anthony Wing-ip Lo, Simon Law, Maira Li Lung
Publikováno v:
Cancer Research. 83:363-363
Background: Esophageal squamous cell carcinoma (ESCC) is one of deadliest esophageal malignancies in Asia. Cancer cachexia is a multifactorial body wasting syndrome and is one of the major causes of death in late-stage patients (1). It is characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b51c63a2a931bafbb35fdfbfb2870317
https://doi.org/10.1158/1538-7445.am2023-363
https://doi.org/10.1158/1538-7445.am2023-363