Ten challenges and opportunities in computational immuno-oncology.

Autor: Bao R; UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA Alan.Hutson@roswellpark.org baor@upmc.edu anantm@emory.edu meerzamd@mail.nih.gov song.liu@roswellpark.org eliezerm_vanallen@dfci.harvard.edu xingyi@chop.edu.; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Hutson A; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA Alan.Hutson@roswellpark.org baor@upmc.edu anantm@emory.edu meerzamd@mail.nih.gov song.liu@roswellpark.org eliezerm_vanallen@dfci.harvard.edu xingyi@chop.edu., Madabhushi A; Emory University, Atlanta, Georgia, USA Alan.Hutson@roswellpark.org baor@upmc.edu anantm@emory.edu meerzamd@mail.nih.gov song.liu@roswellpark.org eliezerm_vanallen@dfci.harvard.edu xingyi@chop.edu.; Georgia Institute of Technology, Atlanta, Georgia, USA.; Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA., Jonsson VD; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, California, USA., Rosario SR; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA., Barnholtz-Sloan JS; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.; Center for Biomedical Informatics & Information Technology, National Cancer Institute, Bethesda, Maryland, USA., Fertig EJ; Department of Oncology, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, Maryland, USA., Marathe H; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA., Harris L; Cancer Diagnosis Program, National Cancer Institute Division of Cancer Treatment and Diagnosis, Bethesda, Maryland, USA., Altreuter J; Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Chen Q; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Rockville, Maryland, USA., Dignam J; Department of Public Health Sciences, University of Chicago Division of the Biological Sciences, Chicago, Illinois, USA., Gentles AJ; Department of Pathology, Stanford University, Stanford, California, USA., Gonzalez-Kozlova E; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Immunology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gnjatic S; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Immunology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Kim E; Informatics and Data Science Program, Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, Maryland, USA., Long M; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA., Morgan M; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA., Ruppin E; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, Maryland, USA., Valen DV; Division of Computing and Mathematical Science, Caltech, Pasadena, California, USA.; Howard Hughes Medical Institute, Chevy Chase, Maryland, USA., Zhang H; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA., Vokes N; Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Meerzaman D; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Rockville, Maryland, USA Alan.Hutson@roswellpark.org baor@upmc.edu anantm@emory.edu meerzamd@mail.nih.gov song.liu@roswellpark.org eliezerm_vanallen@dfci.harvard.edu xingyi@chop.edu., Liu S; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA Alan.Hutson@roswellpark.org baor@upmc.edu anantm@emory.edu meerzamd@mail.nih.gov song.liu@roswellpark.org eliezerm_vanallen@dfci.harvard.edu xingyi@chop.edu., Van Allen EM; Harvard Medical School, Boston, Massachusetts, USA Alan.Hutson@roswellpark.org baor@upmc.edu anantm@emory.edu meerzamd@mail.nih.gov song.liu@roswellpark.org eliezerm_vanallen@dfci.harvard.edu xingyi@chop.edu.; Division of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Xing Y; Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA Alan.Hutson@roswellpark.org baor@upmc.edu anantm@emory.edu meerzamd@mail.nih.gov song.liu@roswellpark.org eliezerm_vanallen@dfci.harvard.edu xingyi@chop.edu.; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 Oct 26; Vol. 12 (10). Date of Electronic Publication: 2024 Oct 26.