Population Pharmacokinetics of the Antimalarial Amodiaquine: a Pooled Analysis To Optimize Dosing

Autor: Ali, Ali Mohamed, Penny, Melissa, Smith, Thomas, Workman, Lesley, Sasi, Philip, Adjei, George O, Aweeka, Francesca, Kiechel, Jean-René, Jullien, Vincent, Rijken, Marcus, Mcgready, Rose, Mwesigwa, Julia, Kristensen, Kim, Stepniewska, Kasia, Tarning, Joel, Barnes, Karen, Denti, Paolo, Massougbodji, Achille, Gansané, Adama, Adeothy, Adicat, Aubouy, Agnès, Ouedraogo, Alphonse, Annerberg, Anna, Bruneel, Arnaud, Phyo, Aung Pyae, Win, Aye Kyi, Benakis, A., Goka, Bamenla, Gourmel, Bernard, Ogutu, Bernhards, Schramm, Birgit, McGee, Bryan, Morgan, Caroline, Obonyo, Charles, Mazinda, Charles, Parzy, D., Ashley, Elizabeth, Baudin, Elisabeth, Juma, Elizabeth, Comte, Eric, Ouedraogo, Esperance, Nosten, François, Sugnaux, F., Cottrell, Gilles, Dorsey, Grant, Carn, Gwenaelle, Kossou, Hortense, Amedome, Hyacinthe, Kalyango, Joan, Faucher, Jean-François, Jones, Joel, Simpson, Julie, Doritchamou, Justin, Kurtzhals, J., Pinoges, Loretxu, Hoegberg, Lotte, BERTAUX, L., Malaika, L. Tshilolo Muepu, Bergstrand, Martin, Alifrangis, Michael, Branger, Michel, Cot, Michel, Cammas, Mireille, Kamya, Moses, Day, Nicholas, White, Nicholas, Taudon, N., Rodrigues, Onike, Chotsiri, Palang, Valeh, Parastou, Houzé, Pascal, Deloron, Philippe, Guérin, Philippe, Rosenthal, Philip, Hsi, Poe, German, Polina, Singhasivanon, Pratap, Smith, Richard, Lwango, R., Sirima, Sodiomon, Parikh, Sunil, Alegre, S. Sese, Clark, Tamara, Sundaygar, Timothy, Drysdale, Troy, Taylor, Walter, Sinou, V., Zolia, Yah

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2018, 62 (10), pp.e02193-17. ⟨10.1128/AAC.02193-17⟩

International audience; Amodiaquine plus artesunate is the recommended antimalarial treatment in many countries where malaria is endemic. However, pediatric doses are largely based on a linear extrapolation from adult doses. We pooled data from previ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3bb3bd18f3fc311c9c6b237e07f75e3e
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03136362

Tolerability and safety of artesunate-amodiaquine and artemether-lumefantrine fixed dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria: two open-label, randomized trials in Nimba County, Liberia.

Autor: Schramm, Birgit¹ birgit.schramm@epicentre.msf.org, Valeh, Parastou¹, Baudin, Elisabeth¹, Mazinda, Charles S.¹, Smith, Richard¹, Pinoges, Loretxu¹, Sundaygar, Timothy¹, Zolia, Yah M.², Jones, Joel J.², Comte, Eric³, Bruneel, Arnaud⁴, Branger, Michel⁵, Jullien, Vincent⁶, Carn, Gwenaelle⁷, Kiechel, Jean-René⁷, Ashley, Elizabeth A.¹, Guérin, Philippe J.^1,8

Publikováno v: Malaria Journal. 2013, Vol. 12 Issue 1, p1-13. 13p. 2 Diagrams, 8 Charts, 1 Graph.

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