Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry

Autor: Amit Kulkarni, Tiago Ferreira, Clemens Bretscher, Annabel Grewenig, Nazim El-Andaloussi, Serena Bonifati, Tiina Marttila, Valérie Palissot, Jubayer A. Hossain, Francisco Azuaje, Hrvoje Miletic, Lars A. R. Ystaas, Anna Golebiewska, Simone P. Niclou, Ralf Roeth, Beate Niesler, Amélie Weiss, Laurent Brino, Antonio Marchini

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Rat H-1 parvovirus (H-1PV) is in clinical development for oncolytic therapy. Here, Kulkarni et al. identify LAMC1 as a modulator of H-1PV cell attachment and entry and find that LAMC1 levels and H-1PV oncolytic activity correlate in 59 tested cancer

Externí odkaz: https://doaj.org/article/e9d685fa483d413282b0592f44b963bf

BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization

Autor: Guy Berchem, Valeŕie Palissot, Céline Gongora, Salwa Sebti, Laetitia K. Linares, Patrice Codogno, Nelly Pirot, Emmanuelle Liaudet-Coopman, Esther Pérez-Gracia, Sophie Pattingre, Fabienne Desmots, Chantal Bauvy, Anne Sophie Bach, Andrew V. Hubberstey, Christine Prébois

Publikováno v: Autophagy
Autophagy, Taylor & Francis, 2014, 10 (7), pp.1341-1342. ⟨10.4161/auto.28979⟩
Autophagy, Taylor & Francis, 2014, 10 (7), pp.1341--2. ⟨10.4161/auto.28979⟩
Autophagy, 2014, 10 (7), pp.1341--2. ⟨10.4161/auto.28979⟩
Biological Sciences Publications

International audience; We recently reported that BAG6/BAT3 (BCL2-associated athanogene 6) is essential for basal and starvation-induced autophagy in E18.5 bag6(-/-) mouse embryos and in mouse embryonic fibroblasts (MEFs) through the modulation of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb112c0207cedcc4b7d8637e3f50229
https://pubmed.ncbi.nlm.nih.gov/24852146