Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Valdemar Priebe"'
Autor:
Eitan Kugler, Shreyas Madiwale, Darren Yong, Julie A. I. Thoms, Yehudit Birger, David B. Sykes, Johannes Schmoellerl, Aneta Drakul, Valdemar Priebe, Muhammad Yassin, Nasma Aqaqe, Avigail Rein, Hila Fishman, Ifat Geron, Chun-Wei Chen, Brian Raught, Qiao Liu, Heather Ogana, Elisabeth Liedke, Jean-Pierre Bourquin, Johannes Zuber, Michael Milyavsky, John Pimanda, Gilbert G. Privé, Shai Izraeli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The ERG (ETS-related gene) transcription factor is linked to various types of cancer, including leukemia. However, the specific ERG domains and co-factors contributing to leukemogenesis are poorly understood. Drug targeting a transcription f
Externí odkaz:
https://doaj.org/article/d7035b0bdc8b4304be06aaa591c4d83a
Autor:
Valdemar Priebe, Aneta Drakul, Stefan Zeyen, Beat Bornhauser, Raffaella Santoro, Jean-Pierre Bourquin
Publikováno v:
HemaSphere, Vol 7, p e88138e3 (2023)
Externí odkaz:
https://doaj.org/article/9e93f6aab3944de2a01ed7df38709821
Autor:
Giulio Sartori, Sara Napoli, Luciano Cascione, Elaine Yee Lin Chung, Valdemar Priebe, Alberto Jesus Arribas, Afua Adjeiwaa Mensah, Michela Dall’Angelo, Chiara Falzarano, Laura Barnabei, Mattia Forcato, Andrea Rinaldi, Silvio Bicciato, Margot Thome, Francesco Bertoni
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Abstract Background Diffuse large B-cell lymphoma (DLBCL) comprises at least two main biologically distinct entities: germinal center B-cell (GCB) and activated B-cell (ABC) subtype. Albeit sharing common lesions, GCB and ABC DLBCL present subtype-sp
Externí odkaz:
https://doaj.org/article/490c1667e613427b8a22fd636cfa21a8
Autor:
Chiara Tarantelli, Lu Zhang, Elisabetta Curti, Eugenio Gaudio, Filippo Spriano, Valdemar Priebe, Luciano Cascione, Alberto J. Arribas, Emanuele Zucca, Davide Rossi, Anastasios Stathis, Francesco Bertoni
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
Externí odkaz:
https://doaj.org/article/8526ea6b4eb945fb95e64418e3fabfdb
Autor:
Valdemar Priebe, Giulio Sartori, Sara Napoli, Elaine Yee Lin Chung, Luciano Cascione, Ivo Kwee, Alberto Jesus Arribas, Afua Adjeiwaa Mensah, Andrea Rinaldi, Maurilio Ponzoni, Emanuele Zucca, Davide Rossi, Dimitar Efremov, Georg Lenz, Margot Thome, Francesco Bertoni
Publikováno v:
Cancers, Vol 12, Iss 7, p 1912 (2020)
Diffuse large B cell lymphoma (DLBCL) is a heterogenous disease that has been distinguished into at least two major molecular entities, the germinal center-like B cell (GCB) DLBCL and activated-like B cell (ABC) DLBCL, based on transcriptome expressi
Externí odkaz:
https://doaj.org/article/0ca635d1c9f5418395e644c03401ced7
Autor:
Francesco Bertoni, Jeffrey A. Toretsky, Brian Lannutti, Anastasios Stathis, Emanuele Zucca, B. Hilda Ye, Davide Genini, Monica Testoni, Ivo Kwee, Andrea Rinaldi, Andrea Cavalli, Saravana P. Selvanathan, Garrett Graham, Giulio Sartori, Valdemar Priebe, Laura Carrassa, Katti Jessen, Sara Napoli, Luciano Cascione, Chiara Tarantelli, Eugenio Gaudio, Elaine Yee Lin Chung, Filippo Spriano
YK-4-279 and TK-216 combinations. For each combination, the table shows the median Combination Index (CI) obtained after exposing cell lines to increasing concentration of two compounds at 8 x 8 concentrations of each compound (removing concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c30ef7f9a26307b66016b74d333ac1
https://doi.org/10.1158/1078-0432.22473042
https://doi.org/10.1158/1078-0432.22473042
Autor:
Francesco Bertoni, Jeffrey A. Toretsky, Brian Lannutti, Anastasios Stathis, Emanuele Zucca, B. Hilda Ye, Davide Genini, Monica Testoni, Ivo Kwee, Andrea Rinaldi, Andrea Cavalli, Saravana P. Selvanathan, Garrett Graham, Giulio Sartori, Valdemar Priebe, Laura Carrassa, Katti Jessen, Sara Napoli, Luciano Cascione, Chiara Tarantelli, Eugenio Gaudio, Elaine Yee Lin Chung, Filippo Spriano
Purpose:Transcription factors are commonly deregulated in cancer, and they have been widely considered as difficult to target due to their nonenzymatic mechanism of action. Altered expression levels of members of the ETS-transcription factors are oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206542a8a12efab2866cc9fcd205d19b
https://doi.org/10.1158/1078-0432.c.6528405
https://doi.org/10.1158/1078-0432.c.6528405
Autor:
Valdemar Priebe, Emanuele Zucca, Andrea Rinaldi, Claudio Pietra, Eugenio Gaudio, Filippo Spriano, Luciano Cascione, Anastasios Stathis, Francesco Bertoni, Luca Aresu, Giulio Sartori, Afua Adjeiwaa Mensah, Giovanna Damia, Emanuela Lovati, Chiara Tarantelli, Elisa Civanelli
Publikováno v:
Blood Adv
Histone deacetylase inhibitors (HDACis) are antitumor agents with distinct efficacy in hematologic tumors. Pracinostat is a pan-HDACi with promising early clinical activity. However, similar to other HDACis, its activity as a single agent is limited.
Autor:
Giulio Sartori, Valdemar Priebe, Luciano Cascione, Elaine Y.L. Chung, Mélanie Favre-Juilland, Sara Napoli, Alberto Arribas, Andrea Rinaldi, Margot Thome Miazza, Francesco Bertoni
Publikováno v:
Blood Cancer Discovery. 3:A14-A14
Introduction. The two ETS transcription factors ETS1 and FLI1 are co-mapped in the 11q24.3 region recurrently gained in up to 25% of diffuse large B cell lymphomas (DLBCL) (Bonetti et al, 2013). The two proteins largely co-regulate a series of genes
Autor:
Ivo Kwee, Laura Carrassa, Monica Testoni, Katti Jessen, B. Hilda Ye, Emanuele Zucca, Filippo Spriano, Davide Genini, Valdemar Priebe, Chiara Tarantelli, Giulio Sartori, Brian J. Lannutti, Saravana P. Selvanathan, Jeffrey A. Toretsky, Sara Napoli, Andrea Cavalli, Elaine Yee Lin Chung, Andrea Rinaldi, Anastasios Stathis, Francesco Bertoni, Eugenio Gaudio, Garrett T. Graham, Luciano Cascione
Publikováno v:
Clinical Cancer Research. 25:5167-5176
Purpose: Transcription factors are commonly deregulated in cancer, and they have been widely considered as difficult to target due to their nonenzymatic mechanism of action. Altered expression levels of members of the ETS-transcription factors are of