Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Valdemar Maximo"'
Autor:
Karina Colombera Peres, Larissa Teodoro, Laís Helena Pereira Amaral, Elisângela Souza Teixeira, Icléia Siqueira Barreto, Leandro Luiz Lopes de Freitas, Valdemar Maximo, Lígia V. Montalli Assumpção, Natassia Elena Bufalo, Laura Sterian Ward
Publikováno v:
Archives of Endocrinology and Metabolism, Vol 65, Iss 2, Pp 172-184 (2021)
ABSTRACT Objective: Abnormalities involving the TGFB1 gene and its receptors are common in several types of cancer and often related to tumor progression. We investigated the role of single nucleotide polymorphisms (SNP) in the susceptibility to canc
Externí odkaz:
https://doaj.org/article/f78f594ab55240ebb7c7a0c8191c32b7
Autor:
Valdemar Maximo, Sule Canberk, Ana Rita Marçal Dantas de Lima, Massimo Bongiovanni, Manuel Sobrinho-Simões, Marcelo Correia, Paula Soares
Publikováno v:
Journal of Molecular Pathology. 3:1-14
DICER1 protein is a member of the ribonuclease (RNAse) III family with a key role in the biogenesis of microRNAs (miRNA) and in microRNA processing, potentially affecting gene regulation at the post-transcriptional level. The role of DICER1 and its r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f71a287bb5f754239ca8d594418cc365
https://doi.org/10.3390/jmp3010001
https://doi.org/10.3390/jmp3010001
Autor:
Sule Canberk, marta ferreira, Carla Oliveira, joana reis, rita barros, luisa pereira, hugo osorio, Elisabete Rios, Paula Soares, Valdemar Maximo
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53a29ae861c6a317d60bef92a38a8953
https://doi.org/10.1530/endoabs.84.op-07-33
https://doi.org/10.1530/endoabs.84.op-07-33
Autor:
Karina Colombera, Peres, Larissa, Teodoro, Laís Helena Pereira, Amaral, Elisângela Souza, Teixeira, Icléia Siqueira, Barreto, Leandro Luiz Lopes, de Freitas, Valdemar, Maximo, Lígia V Montalli, Assumpção, Natassia Elena, Bufalo, Laura Sterian, Ward
Publikováno v:
Archives of endocrinology and metabolism. 65(2)
Abnormalities involving theWe genotypedSNPs rs1800472 and rs1800469 were associated with characteristics of PTC aggressiveness. Effect predictor software analysis of nonsynonymous SNP rs1800472 indicated increasing protein stability and post-translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::233fc4c36c241978e8a820ff5c39eed1
https://pubmed.ncbi.nlm.nih.gov/33905626
https://pubmed.ncbi.nlm.nih.gov/33905626
Autor:
Larissa Teodoro Rabi, Karina Colombera Peres, Matheus Nascimento, Elisangela de Souza Teixeira, Leandro Luiz Lopes de Freitas, Icléia Siqueira Barreto, Murilo Vieira Geraldo, Lígia Vera Montalli Assumpção, Valdemar Máximo, Alfio José Tincani, Natassia Elena Bufalo, Laura Sterian Ward
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract To better understand the relationship among cell adhesion molecules (CAM) and investigate the clinical diagnostic and prognostic application of ICAM-1 (ICAM1), LFA-1 (ITGAL), and L-selectin (SELL) proteins and mRNA corresponding expression i
Externí odkaz:
https://doaj.org/article/5fa9ef53854b43099dc103b604117db6
Autor:
Elisabete Teixeira, Cláudia Fernandes, Maria Bungărdean, Arnaud Da Cruz Paula, Raquel T. Lima, Rui Batista, João Vinagre, Manuel Sobrinho-Simões, Valdemar Máximo, Paula Soares
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1522 (2024)
In a family with Familial Non-Medullary Thyroid Carcinoma (FNMTC), our investigation using Whole-Exome Sequencing (WES) uncovered a novel germline USP42 mutation [p.(Gly486Arg)]. USP42 is known for regulating p53, cell cycle arrest, and apoptosis, an
Externí odkaz:
https://doaj.org/article/996f3778682c4c51b9a5b8294d48016d
Autor:
Sule Canberk, Marcelo Correia, Ana Rita Lima, Massimo Bongiovanni, Manuel Sobrinho-Simões, Paula Soares, Valdemar Máximo
Publikováno v:
Journal of Molecular Pathology, Vol 3, Iss 1, Pp 1-14 (2022)
DICER1 protein is a member of the ribonuclease (RNAse) III family with a key role in the biogenesis of microRNAs (miRNA) and in microRNA processing, potentially affecting gene regulation at the post-transcriptional level. The role of DICER1 and its r
Externí odkaz:
https://doaj.org/article/71478ddba9114ba1951cf475b341e5ab
Autor:
Izabela Fernanda Dal’ Bó, Elisângela Souza Teixeira, Larissa Teodoro Rabi, Karina Colombera Peres, Matheus Nascimento, Maria Izabel Chiamolera, Valdemar Máximo, Natássia Elena Bufalo, Laura Sterian Ward
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Endocrine-disrupting and carcinogenic effects of glyphosate have long been suspected, but little is known about the effect of compounds used in real life at different concentrations, neither in normal nor in thyroid tumor cells. As cancer cells may h
Externí odkaz:
https://doaj.org/article/a667bec7c3c14379b555a9fbc0cfe217
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Familial non-medullary thyroid carcinoma (FNMTC) corresponds to 5-10% of all follicular cell-derived carcinoma (FCDTC). Oncocytic thyroid tumors have an increased incidence in the familial context in comparison with sporadic FCDTC, encompassing benig
Externí odkaz:
https://doaj.org/article/9bae619b189548e7b3e248c63c131887
Autor:
Mafalda Santos, Marta Ferreira, Patrícia Oliveira, Nuno Mendes, Ana André, André F. Vieira, Joana B. Nunes, Joana Carvalho, Sara Rocha, Mafalda Azevedo, Daniel Ferreira, Inês Reis, João Vinagre, Joana Paredes, Alireza Heravi-Moussavi, Jorge Lima, Valdemar Máximo, Angela Burleigh, Calvin Roskelley, Fátima Carneiro, David Huntsman, Carla Oliveira
Publikováno v:
Biology, Vol 11, Iss 7, p 1046 (2022)
Transitions between epithelial and mesenchymal cellular states (EMT/MET) contribute to cancer progression. We hypothesize that EMT followed by MET promotes cell population heterogeneity, favouring tumour growth. We developed an EMT model by on and of
Externí odkaz:
https://doaj.org/article/7302372388394956b9b27c7225a965ca