Výsledky vyhledávání - "Valdemar Maximo"

Akademický článek

Clinical utility of TGFB1 and its receptors (TGFBR1 and TGFBR2) in thyroid nodules: evaluation based on single nucleotide polymorphisms and mRNA analysis

Autor: Karina Colombera Peres, Larissa Teodoro, Laís Helena Pereira Amaral, Elisângela Souza Teixeira, Icléia Siqueira Barreto, Leandro Luiz Lopes de Freitas, Valdemar Maximo, Lígia V. Montalli Assumpção, Natassia Elena Bufalo, Laura Sterian Ward

Publikováno v: Archives of Endocrinology and Metabolism, Vol 65, Iss 2, Pp 172-184 (2021)

ABSTRACT Objective: Abnormalities involving the TGFB1 gene and its receptors are common in several types of cancer and often related to tumor progression. We investigated the role of single nucleotide polymorphisms (SNP) in the susceptibility to canc

Externí odkaz: https://doaj.org/article/f78f594ab55240ebb7c7a0c8191c32b7

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The Multifaceted Profile of Thyroid Disease in the Background of DICER1 Germline and Somatic Mutations: Then, Now and Future Perspectives

Autor: Valdemar Maximo, Sule Canberk, Ana Rita Marçal Dantas de Lima, Massimo Bongiovanni, Manuel Sobrinho-Simões, Marcelo Correia, Paula Soares

Publikováno v: Journal of Molecular Pathology. 3:1-14

DICER1 protein is a member of the ribonuclease (RNAse) III family with a key role in the biogenesis of microRNAs (miRNA) and in microRNA processing, potentially affecting gene regulation at the post-transcriptional level. The role of DICER1 and its r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f71a287bb5f754239ca8d594418cc365
https://doi.org/10.3390/jmp3010001

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Clinical utility of

Autor: Karina Colombera, Peres, Larissa, Teodoro, Laís Helena Pereira, Amaral, Elisângela Souza, Teixeira, Icléia Siqueira, Barreto, Leandro Luiz Lopes, de Freitas, Valdemar, Maximo, Lígia V Montalli, Assumpção, Natassia Elena, Bufalo, Laura Sterian, Ward

Publikováno v: Archives of endocrinology and metabolism. 65(2)

Abnormalities involving theWe genotypedSNPs rs1800472 and rs1800469 were associated with characteristics of PTC aggressiveness. Effect predictor software analysis of nonsynonymous SNP rs1800472 indicated increasing protein stability and post-translat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::233fc4c36c241978e8a820ff5c39eed1
https://pubmed.ncbi.nlm.nih.gov/33905626

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