Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Valdemar L. Andersen"'
Autor:
Valdemar L. Andersen, Mikkel A. Soerensen, Johan Hygum Dam, Niels Langkjaer, Henrik Petersen, Dirk Andreas Bender, Dan Fugloe, Tri Hien Viet Huynh
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract Background The radiofluorinated levodopa analogue 6-[18F]F-l-DOPA (3,4-dihydroxy-6-18F-l-phenylalanine) is a commonly employed radiotracer for PET/CT imaging of multiple oncological and neurological indications. An unusually large number of
Externí odkaz:
https://doaj.org/article/b761850bbba04637b5c7cc66eaa7a272
Autor:
Valdemar L. Andersen, Tri Hien Viet Huynh, Charles Vriamont, Corentin Warnier, Helle W. Hendel, Mikkel A. Sørensen, Julien Masset
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 63:393-403
Prostate-specific membrane antigen (PSMA)-based radioligands for positron emission tomography (PET)/computed tomography (CT) studies represent the gold standard for detection of recurrent prostate cancer (PCa). [68 Ga]PSMA-HBED-CC is a PET radiotrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6541c7e24c4c92e78855b3e24f01aca
https://doi.org/10.1002/jlcr.3846
https://doi.org/10.1002/jlcr.3846
Autor:
Dirk Bender, Mikkel Agerbaek Soerensen, Valdemar L. Andersen, Niels Langkjær, Dan Fugloe, Johan Hygum Dam, Tri Hien Viet Huynh, Henrik Gordon Petersen
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-15 (2021)
Andersen, V L, Soerensen, M A, Dam, J H, Langkjaer, N, Petersen, H, Bender, D A, Fugloe, D & Huynh, T H V 2021, ' GMP production of 6-[ 18 F]Fluoro-l-DOPA for PET/CT imaging by different synthetic routes : a three center experience ', EJNMMI Radiopharmacy and Chemistry, vol. 6, 21 . https://doi.org/10.1186/s41181-021-00135-y
Andersen, V L, Soerensen, M A, Dam, J H, Langkjaer, N, Petersen, H, Bender, D A, Fugloe, D & Huynh, T H V 2021, ' GMP production of 6-[18F]Fluoro-L-DOPA for PET/CT imaging by different synthetic routes : a three center experience ', EJNMMI Radiopharmacy and Chemistry, vol. 6, 21 . https://doi.org/10.1186/s41181-021-00135-y
Andersen, V L, Soerensen, M A, Dam, J H, Langkjaer, N, Petersen, H, Bender, D A, Fugloe, D & Huynh, T H V 2021, ' GMP production of 6-[ 18 F]Fluoro-l-DOPA for PET/CT imaging by different synthetic routes : a three center experience ', EJNMMI Radiopharmacy and Chemistry, vol. 6, 21 . https://doi.org/10.1186/s41181-021-00135-y
Andersen, V L, Soerensen, M A, Dam, J H, Langkjaer, N, Petersen, H, Bender, D A, Fugloe, D & Huynh, T H V 2021, ' GMP production of 6-[18F]Fluoro-L-DOPA for PET/CT imaging by different synthetic routes : a three center experience ', EJNMMI Radiopharmacy and Chemistry, vol. 6, 21 . https://doi.org/10.1186/s41181-021-00135-y
Background The radiofluorinated levodopa analogue 6-[18F]F-l-DOPA (3,4-dihydroxy-6-18F-l-phenylalanine) is a commonly employed radiotracer for PET/CT imaging of multiple oncological and neurological indications. An unusually large number of different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f428396aecbb51829aa8b2c1450050
https://doi.org/10.1186/s41181-021-00135-y
https://doi.org/10.1186/s41181-021-00135-y
Autor:
Mikkel A, Sørensen, Valdemar L, Andersen, Helle Westergren, Hendel, Charles, Vriamont, Corentin, Warnier, Julien, Masset, Tri Hien Viet, Huynh
Publikováno v:
Journal of labelled compoundsradiopharmaceuticalsREFERENCES. 63(8)
Prostate-specific membrane antigen (PSMA)-based radioligands for positron emission tomography (PET)/computed tomography (CT) studies represent the gold standard for detection of recurrent prostate cancer (PCa). [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::733527c4cd6c95a8660804388c60bd22
https://pubmed.ncbi.nlm.nih.gov/32374450
https://pubmed.ncbi.nlm.nih.gov/32374450
Autor:
Gitte M. Knudsen, Nils T. Nyberg, Pantaleo Di Pilato, Szabolcs Lehel, E. Johanna L. Stéen, Jesper L. Kristensen, Matthias M. Herth, Valdemar L. Andersen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:319-322
In drug discovery, lipophilicity is a key parameter for drug optimization. Lipophilicity determinations can be both work and time consuming, especially for non-UV active compounds. Herein, an improved and simple 1H NMR-based method is described to es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2411ab25f3986888bf5e167a2ea7592
https://doi.org/10.1016/j.bmcl.2016.11.048
https://doi.org/10.1016/j.bmcl.2016.11.048
Autor:
Agnete Dyssegaard, Jesper L. Kristensen, Hanne D. Hansen, Szabolcs Lehel, Matthias M. Herth, Gitte M. Knudsen, Janus H. Magnussen, Nikolas Stroth, Valdemar L. Andersen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1901-1904
E-55888 has been identified as a selective serotonin 7 (5-HT 7 ) receptor agonist. In this study, we describe the synthesis, radiolabeling and in vivo evaluation of [ 11 C]E-55888 as a radioligand for positron emission tomography (PET) imaging. [ 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b2e4893f4eebadbceda4d98e762faa
https://doi.org/10.1016/j.bmcl.2015.03.039
https://doi.org/10.1016/j.bmcl.2015.03.039
Autor:
Nikolas Stroth, Matthias M. Herth, Gitte M. Knudsen, Szabolcs Lehel, Agnete Dyssegaard, Jesper L. Kristensen, Balázs Volk, Anders Ettrup, Hanne D. Hansen, Valdemar L. Andersen, Per Svenningsson
Publikováno v:
Journal of Medicinal Chemistry. 58:3631-3636
We have investigated several oxindole derivatives in the pursuit of a 5-HT7 receptor PET ligand. Herein the synthesis, chiral separation, and pharmacological profiling of two possible PET candidates toward a wide selection of CNS-targets are detailed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb73c12c5ed5b127e8381080116bdf30
https://doi.org/10.1021/acs.jmedchem.5b00095
https://doi.org/10.1021/acs.jmedchem.5b00095
Autor:
Valdemar L. Andersen, Hanne D. Hansen, Gitte M. Knudsen, Matthias M. Herth, Jesper L. Kristensen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:2408-2411
Vortioxetine is a new multi-modal drug against major depressive disorder with high affinity for a range of different serotonergic targets in the CNS. We report the (11)C-labeling of vortioxetine with [(11)C]MeI using a Suzuki-protocol that allows for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb260935dfd6a037b64ac0ad17b2249
https://doi.org/10.1016/j.bmcl.2014.04.044
https://doi.org/10.1016/j.bmcl.2014.04.044
Autor:
Jesper L. Kristensen, Gitte M. Knudsen, Matthias M. Herth, Valdemar L. Andersen, Szabolcs Lehel
Publikováno v:
Tetrahedron Letters. 54:213-216
Cross-couplings are an alternative to conventional 11C-methylations which are generally employed in PET tracer synthesis. Therefore, we set out to develop a general procedure for the synthesis of para-11CH3 labeled aromatic amines from the correspond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5741645fd658cbe8075c5aed465105f
https://doi.org/10.1016/j.tetlet.2012.11.001
https://doi.org/10.1016/j.tetlet.2012.11.001
Autor:
E Johanna L, Stéen, Nils, Nyberg, Szabolcs, Lehel, Valdemar L, Andersen, Pantaleo, Di Pilato, Gitte M, Knudsen, Jesper L, Kristensen, Matthias M, Herth
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(2)
In drug discovery, lipophilicity is a key parameter for drug optimization. Lipophilicity determinations can be both work and time consuming, especially for non-UV active compounds. Herein, an improved and simple 1H NMR-based method is described to es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e07a1712830a85102d618afc81c6bcd8
https://pubmed.ncbi.nlm.nih.gov/27908763
https://pubmed.ncbi.nlm.nih.gov/27908763