Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Valbuena GN"'
Autor:
Koppens, MAJ, Davis, H, Valbuena, GN, Mulholland, E, Simmons, A, Nasreddin, N, East, J, Friedrich, M, Antanaviciute, A, Leedham, S
Background and aims: In homeostasis, intestinal cell fate is controlled by balanced gradients of morphogen signalling. The Bone Morphogenetic Protein (BMP) pathway has a physiological, pro-differentiation role, predominantly inferred through previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::5eac93256426419c495ce2abfaadd46b
https://ora.ox.ac.uk/objects/uuid:c86699c6-01fb-4ada-b7b7-d89a76caf869
https://ora.ox.ac.uk/objects/uuid:c86699c6-01fb-4ada-b7b7-d89a76caf869
Autor:
Beach C, MacLean D, Majorova D, Melemenidis S, Nambiar DK, Kim RK, Valbuena GN, Guglietta S, Krieg C, Darvish-Damavandi M, Suwa T, Easton A, Hillson LV, McCulloch AK, McMahon RK, Pennel K, Edwards J, O'Cathail SM, Roxburgh CS, Domingo E, Moon EJ, Jiang D, Jiang Y, Zhang Q, Koong AC, Woodruff TM, Graves EE, Maughan T, Buczacki SJ, Stucki M, Le QT, Leedham SJ, Giaccia AJ, Olcina MM
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2024 Aug 15; Vol. 134 (16). Date of Electronic Publication: 2024 Aug 15.
Autor:
Beach C; Department of Oncology, University of Oxford, Oxford, United Kingdom., MacLean D; Department of Oncology, University of Oxford, Oxford, United Kingdom., Majorova D; Department of Oncology, University of Oxford, Oxford, United Kingdom., Melemenidis S; Department of Radiation Oncology, Stanford University, Stanford, California, USA., Nambiar DK; Department of Radiation Oncology, Stanford University, Stanford, California, USA., Kim RK; Department of Radiation Oncology, Stanford University, Stanford, California, USA., Valbuena GN; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Guglietta S; Department of Regenerative Medicine and Cell Biology.; Hollings Cancer Center, and., Krieg C; Hollings Cancer Center, and.; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, USA., Darvish-Damavandi M; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom., Suwa T; Department of Oncology, University of Oxford, Oxford, United Kingdom., Easton A; Department of Oncology, University of Oxford, Oxford, United Kingdom., Hillson LV; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., McCulloch AK; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., McMahon RK; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Pennel K; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Edwards J; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., O'Cathail SM; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Roxburgh CS; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Domingo E; Department of Oncology, University of Oxford, Oxford, United Kingdom., Moon EJ; Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Radiation Oncology, Stanford University, Stanford, California, USA., Jiang D; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Jiang Y; Department of Oncology, University of Oxford, Oxford, United Kingdom., Zhang Q; Department of Oncology, University of Oxford, Oxford, United Kingdom., Koong AC; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Woodruff TM; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Graves EE; Department of Radiation Oncology, Stanford University, Stanford, California, USA., Maughan T; Department of Oncology, University of Oxford, Oxford, United Kingdom., Buczacki SJ; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom., Stucki M; Department of Gynecology, University of Zurich, Schlieren, Switzerland., Le QT; Department of Radiation Oncology, Stanford University, Stanford, California, USA., Leedham SJ; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Giaccia AJ; Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Radiation Oncology, Stanford University, Stanford, California, USA., Olcina MM; Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Radiation Oncology, Stanford University, Stanford, California, USA.; Department of Gynecology, University of Zurich, Schlieren, Switzerland.
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2023 Dec 01; Vol. 133 (23). Date of Electronic Publication: 2023 Dec 01.
Autor:
Gil Vazquez E, Nasreddin N, Valbuena GN, Mulholland EJ, Belnoue-Davis HL, Eggington HR, Schenck RO, Wouters VM, Wirapati P, Gilroy K, Lannagan TRM, Flanagan DJ, Najumudeen AK, Omwenga S, McCorry AMB, Easton A, Koelzer VH, East JE, Morton D, Trusolino L, Maughan T, Campbell AD, Loughrey MB, Dunne PD, Tsantoulis P, Huels DJ, Tejpar S, Sansom OJ, Leedham SJ
Publikováno v:
Cell stem cell [Cell Stem Cell] 2022 Nov 03; Vol. 29 (11), pp. 1612.
Autor:
Vasquez EG; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK., Nasreddin N; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK., Valbuena GN; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK., Mulholland EJ; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK., Belnoue-Davis HL; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK., Eggington HR; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK., Schenck RO; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK., Wouters VM; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Meibergdreef 9, 1105 Amsterdam, the Netherlands; Oncode Institute, Meibergdreef 9, 1105 Amsterdam, the Netherlands., Wirapati P; Swiss Institute for Bioinformatics, University of Lausanne, Lausanne, Switzerland., Gilroy K; Cancer Research UK Beatson Institute, Glasgow, UK., Lannagan TRM; Cancer Research UK Beatson Institute, Glasgow, UK., Flanagan DJ; Cancer Research UK Beatson Institute, Glasgow, UK., Najumudeen AK; Cancer Research UK Beatson Institute, Glasgow, UK., Omwenga S; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK., McCorry AMB; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Easton A; Department of Oncology, Old Road Campus Research Building, Roosevelt Drive, University of Oxford, Oxford, UK., Koelzer VH; Department of Pathology and Molecular Pathology, University and University Hospital Zürich, Rämistrasse 100, 8006 Zürich, Switzerland., East JE; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, and Oxford NIHR Biomedical Research Centre, Oxford, UK., Morton D; Academic Department of Surgery, University of Birmingham, Birmingham, UK., Trusolino L; Candiolo Cancer Institute FPO IRCCS, 10060 Candiolo, Torino, Italy., Maughan T; Department of Oncology, Old Road Campus Research Building, Roosevelt Drive, University of Oxford, Oxford, UK., Campbell AD; Cancer Research UK Beatson Institute, Glasgow, UK., Loughrey MB; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Dunne PD; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Tsantoulis P; University of Geneva and Department of Oncology, Hôpitaux Universitaires de Genève, Geneva, Switzerland., Huels DJ; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Meibergdreef 9, 1105 Amsterdam, the Netherlands; Oncode Institute, Meibergdreef 9, 1105 Amsterdam, the Netherlands., Tejpar S; Molecular Digestive Oncology Unit, KU Leuven, Leuven, Belgium., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Leedham SJ; Wellcome Centre Human Genetics, Roosevelt Drive, University of Oxford, Oxford, UK; Department of Pathology and Molecular Pathology, University and University Hospital Zürich, Rämistrasse 100, 8006 Zürich, Switzerland. Electronic address: simon.leedham@well.ox.ac.uk.
Publikováno v:
Cell stem cell [Cell Stem Cell] 2022 Aug 04; Vol. 29 (8), pp. 1213-1228.e8.
Autor:
Nijhuis A; Department of Surgery & Cancer, Imperial College London, London, UK., Sikka A; Department of Surgery & Cancer, Imperial College London, London, UK., Yogev O; Division of Clinical Studies, The Institute of Cancer Research, London, UK., Herendi L; Department of Surgery & Cancer, Imperial College London, London, UK., Balcells C; Department of Surgery & Cancer, Imperial College London, London, UK., Ma Y; Department of Surgery & Cancer, Imperial College London, London, UK., Poon E; Division of Clinical Studies, The Institute of Cancer Research, London, UK., Eckold C; Department of Surgery & Cancer, Imperial College London, London, UK., Valbuena GN; Department of Surgery & Cancer, Imperial College London, London, UK., Xu Y; Department of Surgery & Cancer, Imperial College London, London, UK., Liu Y; Department of Surgery & Cancer, Imperial College London, London, UK., da Costa BM; Division of Clinical Studies, The Institute of Cancer Research, London, UK., Gruet M; Department of Surgery & Cancer, Imperial College London, London, UK., Wickremesinghe C; Department of Surgery & Cancer, Imperial College London, London, UK., Benito A; Department of Surgery & Cancer, Imperial College London, London, UK., Kramer H; Medical Research Council London Institute of Medical Science, London, UK., Montoya A; Medical Research Council London Institute of Medical Science, London, UK., Carling D; Medical Research Council London Institute of Medical Science, London, UK., Want EJ; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Jamin Y; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London and Royal Marsden NHS Trust, London, UK., Chesler L; Division of Clinical Studies, The Institute of Cancer Research, London, UK., Keun HC; Department of Surgery & Cancer, Imperial College London, London, UK. h.keun@imperial.ac.uk.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK. h.keun@imperial.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2022 Mar 16; Vol. 13 (1), pp. 1380. Date of Electronic Publication: 2022 Mar 16.
Autor:
Rana S; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, W12 0NN, UK., Valbuena GN; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Curry E; GSK, Stevenage, SG1 2NY, UK., Bevan CL; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, W12 0NN, UK. charlotte.bevan@imperial.ac.uk., Keun HC; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, W12 0NN, UK. h.keun@imperial.ac.uk.
Publikováno v:
British journal of cancer [Br J Cancer] 2022 Feb; Vol. 126 (3), pp. 502-513. Date of Electronic Publication: 2022 Jan 12.
Autor:
Koppens MAJ; Intestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, United Kingdom., Davis H; Intestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, United Kingdom., Valbuena GN; Intestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, United Kingdom., Mulholland EJ; Intestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, United Kingdom., Nasreddin N; Intestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, United Kingdom., Colombe M; Li Ka Shing Centre, Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Antanaviciute A; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom; Medical Research Council Weatherall Institute of Molecular Medicine Centre for Computational Biology, Medical Research Council Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom., Biswas S; Intestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, United Kingdom., Friedrich M; The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom., Lee L; Cancer Genetics and Evolution Laboratory, Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Wang LM; Department of Laboratory Medicine, Changi General Hospital, SingHealth, Singapore, Singapore., Koelzer VH; Department of Pathology and Molecular Pathology, University Hospital Zürich, Zürich, Switzerland; Department of Oncology and Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., East JE; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, and Oxford National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom., Simmons A; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, and Oxford National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom., Winton DJ; Li Ka Shing Centre, Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Leedham SJ; Intestinal Stem Cell Biology Lab, Wellcome Centre Human Genetics, University of Oxford, Oxford, United Kingdom; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, and Oxford National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom. Electronic address: simon.leedham@well.ox.ac.uk.
Publikováno v:
Gastroenterology [Gastroenterology] 2021 Jul; Vol. 161 (1), pp. 239-254.e9. Date of Electronic Publication: 2021 Apr 02.
Autor:
Braga M; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Kaliszczak M; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Carroll L; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Schug ZT; Cancer Metabolism Research Unit, Cancer Research UK Beatson Institute, Switchback Rd, Glasgow G61 1BD, UK.; Molecular and Cellular Oncogenesis, Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA., Heinzmann K; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Baxan N; Biological Imaging Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Benito A; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Valbuena GN; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Stribbling S; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Beckley A; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Mackay G; Cancer Metabolism Research Unit, Cancer Research UK Beatson Institute, Switchback Rd, Glasgow G61 1BD, UK., Mauri F; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Latigo J; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Barnes C; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Keun H; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Gottlieb E; Cancer Metabolism Research Unit, Cancer Research UK Beatson Institute, Switchback Rd, Glasgow G61 1BD, UK., Aboagye EO; Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK.
Publikováno v:
Cancers [Cancers (Basel)] 2020 Jun 26; Vol. 12 (6). Date of Electronic Publication: 2020 Jun 26.
Autor:
Valbuena GN; Department of Surgery and Cancer, Imperial College London, London, United Kingdom., Cantoni L; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Tortarolo M; Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Bendotti C; Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Keun HC; Department of Surgery and Cancer, Imperial College London, London, United Kingdom.
Publikováno v:
Frontiers in neuroscience [Front Neurosci] 2019 Dec 10; Vol. 13, pp. 1276. Date of Electronic Publication: 2019 Dec 10 (Print Publication: 2019).