Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vala, Kafil"'
Autor:
Javid Shahbazi, Vala Kafil, Mohammad Reza Rashidi, Hadi Valizadeh, Davoud Asgari, Jaleh Barar, Mostafa Heidari Majd, Yadollah Omidi
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 3, Iss 1, Pp 189-195 (2013)
Purpose: To achieve simultaneous imaging and therapy potentials, targeted fluoromagnetic nanoparticles were synthesized and examined in human breast cancer MCF-7 cells. Methods: Fe3O4 nanoparticles (NPs) were synthesized through thermal decomposition
Externí odkaz:
https://doaj.org/article/40fe19b257914514a9185f28b2a762fb
Autor:
Jaleh Barar, Sina Atashpaz, Abolfazl Barzegari, Vala Kafil, Sepideh Zununi Vahed, Farzaneh Soltanzad, Sara Samadi Shams
Publikováno v:
BioImpacts, Vol 1, Iss 3, Pp 183-187 (2011)
Introduction: Today, with the tremendous potential of genomics and other recent advances in science, the role of science to improve reliable DNA extraction methods is more relevant than ever before. The ideal process for genomic DNA extraction demand
Externí odkaz:
https://doaj.org/article/0f50d1111b3b46d5b34a3fc746ceb1ab
Autor:
Yadollah Omidi, Vala Kafil
Publikováno v:
BioImpacts, Vol 1, Iss 1, Pp 23-30 (2011)
Introduction: Polyethylenimine (PEI), as a nonviral cationic polymer, has been widely used as gene delivery nanosystem. Although a number of investigations have highlighted its toxic impacts on target cells through induction of apoptosis/necrosis, st
Externí odkaz:
https://doaj.org/article/d5502323dfee4c079bf42bb13b9ed5fd
Publikováno v:
Journal of drug targeting. 28(10)
Monoclonal antibodies (mAbs) are a swiftly growing class of targeted therapeutics for malignancies. After their first advent, the antibody (Ab) engineering trail has shown an evolutionary trajectory - from the rodent-derived Abs to the chimeric, huma
Publikováno v:
RSC Advances. 5:18041-18050
In the current study, we report on the bioactive compounds isolated from the roots of Salvia sahendica Boiss and Buhse using bioassay-guided procedures and their biological effects against MCF-7 breast carcinoma cells. In comparison with other solven
Autor:
Alaleh Abadpour, Jaleh Barar, Mohammad-Reza Rashidi, Javid Shahbazi Mojarrad, Mostafa Heidari Majd, Yadollah Omidi, George Coukos, Davoud Asgari, Hadi Valizadeh, Efat Moumivand, Vala Kafil
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 106:117-125
Magnetic nanoparticles (MNPs) have been widely used as drug delivery nanosystems and contrast agent for imaging and detection. To engineer multifunctional nanomedicines for simultaneous imaging and therapy of cancer cells, in the current study, we sy
Specific targeting of cancer cells by multifunctional mitoxantrone-conjugated magnetic nanoparticles
Autor:
George Coukos, Mostafa Heidari Majd, Vala Kafil, Hadi Valizadeh, Yadollah Omidi, Jaleh Barar, Davoud Asgari
Publikováno v:
Journal of Drug Targeting. 21:328-340
We report on the synthesis of bifunctional mitoxantrone (MTX)-grafted magnetic nanoparticles (MNPs) modified by dopamine-polyethylene glycol-folic acid (DPA-PEG-FA) for targeted imaging and therapy of cancer. MNPs (~7-10 nm) were synthesized using th
Autor:
Sara, Samadi Shams, Sepideh, Zununi Vahed, Farzaneh, Soltanzad, Vala, Kafil, Abolfazl, Barzegari, Sina, Atashpaz, Jaleh, Barar
Publikováno v:
BioImpacts, Vol 1, Iss 3, Pp 183-187 (2011)
Introduction: Today, with the tremendous potential of genomics and other recent advances in science, the role of science to improve reliable DNA extraction methods is more relevant than ever before. The ideal process for genomic DNA extraction demand
Autor:
Mostafa Heidari Majd, George Coukos, Davoud Asgari, Sajjad Khani, Jaleh Barar, Yadollah Omidi, Vala Kafil, Abolfazl Barzegari, Mohammad Johari-Ahar
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, vol. 13, no. 1, pp. 26
Journal of Nanobiotechnology, vol. 13, no. 1, pp. 26
BACKGROUND: Targeted delivery of anticancer chemotherapeutics such as mitoxantrone (MTX) can significantly intensify their cytotoxic effects selectively in solid tumors such as breast cancer. In the current study, folic acid (FA)-armed and MTX-conjug
Publikováno v:
Medical hypotheses. 81(1)
Monoclonal antibodies (mAbs) are currently among the best remedies in the treatment of cancer disorders. Almost 12 anti-cancer therapeutic mAbs have been approved for clinical applications. Although mAbs have been found to target specific antigens, n