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pro vyhledávání: '"Val Fajado"'
Autor:
Khuchua Zaza, Danny V. Jeyaraju, Mingjing Xu, Neil MacLean, Ayesh K. Seneviratne, Zhenyue Hao, Juan J. Aristizabal Henao, Rose Hurren, Steven M. Claypool, Xioaming Wang, Paul J. LeBlanc, Raphaël Chouinard-Watkins, Aaron D. Schimmer, Val Fajado, Ken D. Stark, Richard P. Bazinet, G. Wei Xu, Sejin Kim, Marcela Gronda, Caitlin Schafer
Publikováno v:
Blood. 130:788-788
AML cells have unique mitochondrial characteristics with an increased reliance on mitochondrial metabolism and oxidative phosphorylation. To identify new biological vulnerabilities in the mitochondria of AML, we conducted a CRISPR knockout screen. CA