Exploiting Leishmania —Primed Dendritic Cells as Potential Immunomodulators of Canine Immune Response.

Autor: Valério-Bolas, Ana¹ (AUTHOR) ana.bolas@ihmt.unl.pt, Meunier, Mafalda¹ (AUTHOR) a21001221@ihmt.unl.pt, Palma-Marques, Joana¹ (AUTHOR) joanapmarques@ihmt.unl.pt, Rodrigues, Armanda¹ (AUTHOR) armanda.rodrigues@ihmt.unl.pt, Santos, Ana Margarida² (AUTHOR) alves.jca@gnr.pt, Nunes, Telmo³ (AUTHOR) telmonunes@hotmail.com, Ferreira, Rui⁴ (AUTHOR), Armada, Ana¹ (AUTHOR) aarmada@ihmt.unl.pt, Alves, João Carlos² (AUTHOR), Antunes, Wilson⁵ (AUTHOR) antunez.wdta@gmail.com, Cardoso, Inês⁴ (AUTHOR), Mesquita-Gabriel, Sofia¹ (AUTHOR) a21000811@ihmt.unl.pt, Lobo, Lis¹ (AUTHOR) lis.lobo@ihmt.unl.pt, Alexandre-Pires, Graça^6,7 (AUTHOR) gpires@fmv.ulisboa.pt, Marques, Luís⁸ (AUTHOR), Pereira da Fonseca, Isabel^6,7 (AUTHOR) ifonseca@fmv.ulisboa.pt, Santos-Gomes, Gabriela¹ (AUTHOR) santosgomes@ihmt.unl.pt

Publikováno v: Cells (2073-4409). Mar2024, Vol. 13 Issue 5, p445. 24p.

Exploiting Leishmania—Primed Dendritic Cells as Potential Immunomodulators of Canine Immune Response

Autor: Ana Valério-Bolas, Mafalda Meunier, Joana Palma-Marques, Armanda Rodrigues, Ana Margarida Santos, Telmo Nunes, Rui Ferreira, Ana Armada, João Carlos Alves, Wilson Antunes, Inês Cardoso, Sofia Mesquita-Gabriel, Lis Lobo, Graça Alexandre-Pires, Luís Marques, Isabel Pereira da Fonseca, Gabriela Santos-Gomes

Publikováno v: Cells, Vol 13, Iss 5, p 445 (2024)

Dendritic cells (DCs) capture pathogens and process antigens, playing a crucial role in activating naïve T cells, bridging the gap between innate and acquired immunity. However, little is known about DC activation when facing Leishmania parasites. T

Externí odkaz: https://doaj.org/article/3cfa575b2f8c474d846ca4cf8f2f3d70

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Zoonotic Visceral Leishmaniasis: New Insights on Innate Immune Response by Blood Macrophages and Liver Kupffer Cells to Leishmania infantum Parasites

Autor: Armanda Viana Rodrigues, Ana Valério-Bolas, Graça Alexandre-Pires, Maria Aires Pereira, Telmo Nunes, Dário Ligeiro, Isabel Pereira da Fonseca, Gabriela Santos-Gomes

Publikováno v: Biology, Vol 11, Iss 1, p 100 (2022)

L. infantum is the aetiological agent of zoonotic visceral leishmaniasis (ZVL), a disease that affects humans and dogs. Leishmania parasites are well adapted to aggressive conditions inside the phagolysosome and can control the immune activation of m

Externí odkaz: https://doaj.org/article/ec7b5cef82d24e20b752605439f95720

Leishmania infantum exerts immunomodulation in canine Kupffer cells reverted by meglumine antimoniate

Autor: Rodrigues, A., Santos-Mateus, D., Alexandre-Pires, G., Valério-Bolas, A., Rafael-Fernandes, M., Pereira, M.A., Ligeiro, D., de Jesus, J., Alves-Azevedo, R., Lopes-Ventura, S., Santos, M., Tomás, A.M., Pereira da Fonseca, I., Santos-Gomes, G.

Publikováno v: In Comparative Immunology, Microbiology and Infectious Diseases December 2017 55:42-52