Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Valérie Vouret"'
Autor:
Catalina Abad, Mélanie Demeules, Charlotte Guillou, Henri Gondé, Rachid Zoubairi, Yossan-Var Tan, Carolina Pinto-Espinoza, Waldemar Schäfer, Anna Marei Mann, Valérie Vouret-Craviari, Friedrich Koch-Nolte, Sahil Adriouch
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background The pro-inflammatory ATP-gated P2X7 receptor is widely expressed by immune and non-immune cells. Nanobodies targeting P2X7, with potentiating or antagonistic effects, have been developed. Adeno-associated virus (AAV)-mediated gene
Externí odkaz:
https://doaj.org/article/a3c490df818f4f30a4f057600fb6ee07
Publikováno v:
Biological Procedures Online, Vol 25, Iss 1, Pp 1-10 (2023)
Abstract Background P2RX7 is a purinergic receptor with pleiotropic activities that is activated by high levels of extracellular ATP that are found in inflamed tissues. P2RX7 has immunomodulatory and anti-tumor proprieties and is therefore a therapeu
Externí odkaz:
https://doaj.org/article/eb393dad912e4505bc5ee6e11d940244
Autor:
Wassila Khatir, Olivier Humbert, Jonathan Benzaquen, Christophe Bontoux, Jaap Neels, Léa Berland, Fabian Andrés Gallardo Rivera, Maryline Allegra, Myriam Salah, Virginie Tanga, Olivier Bordone, Julien Fayada, Virginie Lespinet‐Fabre, Doriane Bohly, Elodie Long‐Mira, Sandra Lassalle, Valérie Vouret, Patrick Brest, Baharia Mograbi, Charlotte Maniel, Josiane Otto, Jacques Boutros, Simon Heeke, Véronique Hofman, Charles‐Hugo Marquette, Paul Hofman, Marius Ilié
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/d923552fc5494c448b84dcf8daffc8a8
Autor:
Laetitia Douguet, Serena Janho dit Hreich, Jonathan Benzaquen, Laetitia Seguin, Thierry Juhel, Xavier Dezitter, Christophe Duranton, Bernhard Ryffel, Jean Kanellopoulos, Cecile Delarasse, Nicolas Renault, Christophe Furman, Germain Homerin, Chloé Féral, Julien Cherfils-Vicini, Régis Millet, Sahil Adriouch, Alina Ghinet, Paul Hofman, Valérie Vouret-Craviari
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
A limited percentage of patients with non-small cell lung cancer respond to immunotherapy. Here the authors show that HEI3090, a chemical positive modulator of the purinergic P2RX7 receptor, promotes IL-18 mediated anti-tumor immune responses and sen
Externí odkaz:
https://doaj.org/article/d9f2cc20554a4d0e92405e7e329a31b4
Autor:
Jonathan Benzaquen, Simon Heeke, Séréna Janho dit Hreich, Laetitia Douguet, Charles Hugo Marquette, Paul Hofman, Valérie Vouret-Craviari
Publikováno v:
Biomedical Journal, Vol 42, Iss 3, Pp 141-154 (2019)
Alternative splicing (AS) tremendously increases the use of genetic information by generating protein isoforms that differ in protein–protein interactions, catalytic activity and/or subcellular localization. This review is not dedicated to AS in ge
Externí odkaz:
https://doaj.org/article/06da24b2ff5d4ebe99ad93315d4f7670
Autor:
Abderrahman Chargui, Annabelle Cesaro, Sanda Mimouna, Mohamed Fareh, Patrick Brest, Philippe Naquet, Arlette Darfeuille-Michaud, Xavier Hébuterne, Baharia Mograbi, Valérie Vouret-Craviari, Paul Hofman
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51727 (2012)
Invading bacteria are recognized, captured and killed by a specialized form of autophagy, called xenophagy. Recently, defects in xenophagy in Crohn's disease (CD) have been implicated in the pathogenesis of human chronic inflammatory diseases of unce
Externí odkaz:
https://doaj.org/article/f076d6596489462884117374c7efc47d
Autor:
Gaëlle Cane, Vanessa Liévin-Le Moal, Gilles Pagès, Alain L Servin, Paul Hofman, Valérie Vouret-Craviari
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1359 (2007)
BACKGROUND: Angiogenesis has been recently described as a novel component of inflammatory bowel disease pathogenesis. The level of vascular endothelial growth factor (VEGF) has been found increased in Crohn's disease and ulcerative colitis mucosa. To
Externí odkaz:
https://doaj.org/article/18924ce530c84a38bb03d46ce15a605b
Autor:
Baharia Mograbi, Paul Hofman, Georges F. Carle, Daniel J. Klionsky, Valérie Vouret-Craviari, Patrick Brest, Corinne Bertolotto, Sophie Barale, Michel Tauc, Isabelle Rubera, Marius Ilie, Sandy Giuliano, Florence Pedeutour, Elisabeth Corcelle–Termeau, Abderrahman Chargui, Michaël Cerezo, Amine Belaid
PDF file - 3250K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f8122c28e504742393606d04e3cf98
https://doi.org/10.1158/0008-5472.22396746
https://doi.org/10.1158/0008-5472.22396746
Autor:
Baharia Mograbi, Paul Hofman, Georges F. Carle, Daniel J. Klionsky, Valérie Vouret-Craviari, Patrick Brest, Corinne Bertolotto, Sophie Barale, Michel Tauc, Isabelle Rubera, Marius Ilie, Sandy Giuliano, Florence Pedeutour, Elisabeth Corcelle–Termeau, Abderrahman Chargui, Michaël Cerezo, Amine Belaid
Degradation of signaling proteins is one of the most powerful tumor-suppressive mechanisms by which a cell can control its own growth. Here, we identify RHOA as the molecular target by which autophagy maintains genomic stability. Specifically, inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ad081eb95e14eb1cdf3393556521bf
https://doi.org/10.1158/0008-5472.c.6504645
https://doi.org/10.1158/0008-5472.c.6504645
Autor:
Baharia Mograbi, Paul Hofman, Georges F. Carle, Daniel J. Klionsky, Valérie Vouret-Craviari, Patrick Brest, Corinne Bertolotto, Sophie Barale, Michel Tauc, Isabelle Rubera, Marius Ilie, Sandy Giuliano, Florence Pedeutour, Elisabeth Corcelle–Termeau, Abderrahman Chargui, Michaël Cerezo, Amine Belaid
AVI file - 5901K, Video 5 (related to Fig. 2G) is a time-lapse recording of a mononucleate a3-/- cell that formed a tetranucleate cell after two rounds of abortive mitosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d662babdd4bf726769eb9d7187edbb
https://doi.org/10.1158/0008-5472.22396731
https://doi.org/10.1158/0008-5472.22396731