Zobrazeno 1 - 10
of 632
pro vyhledávání: '"Valérie Paradis"'
Autor:
Arnaud Nze Ossima, Angélique Brzustowski, Valérie Paradis, Bernard Van Beers, Catherine Postic, Cédric Laouénan, Stanislas Pol, Laurent Castéra, Jean-François Gautier, Sebastien Czernichow, Anais Vallet-Pichard, Etienne Larger, Lawrence Serfaty, Marie Zins, Dominique Valla, Isabelle Durand Zaleski
Publikováno v:
Clinical Diabetes and Endocrinology, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Background & aims Despite its high prevalence in the western world metabolic dysfunction-associated steatotic liver disease (MASLD) does not benefit from targeted pharmacological therapy. We measured healthcare utilisation and identified fac
Externí odkaz:
https://doaj.org/article/8ed7bd9dbb9d4f9db096210ffdfead21
Autor:
Sonia Frendi, Chloé Martineau, Hélène Cazier, Rémy Nicolle, Anaïs Chassac, Miguel Albuquerque, Jérôme Raffenne, Julie Le Faouder, Valérie Paradis, Jérôme Cros, Anne Couvelard, Vinciane Rebours
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Although pancreatic precancerous lesions are known to be related to obesity and fatty pancreatic infiltration, the mechanisms remain unclear. We assessed the role of fatty infiltration in the process of pancreatic oncogenesis and obesity. A
Externí odkaz:
https://doaj.org/article/43883c2326d1432e9d151e071d492431
Autor:
Maryline Roy, Anne Dumay, Sandrine Adiba, Sylvana Rozes, Seiki Kobayashi, Valérie Paradis, Catherine Postic, Dominique Rainteau, Eric Ogier-Denis, Maude Le Gall, Ulrich Meinzer, Emilie Viennois, Maite Casado-Bedmar, Alexis Mosca, Jean-Pierre Hugot
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Metabolic syndrome (MetS) is a cluster of several human conditions including abdominal obesity, hypertension, dyslipidemia, and hyperglycemia, all of which are risk factors of type 2 diabetes, cardiovascular disease, and metabolic dysfunction-associa
Externí odkaz:
https://doaj.org/article/4f158aff9f9b43198c02400b9d40dc5a
Autor:
Julien Calderaro, Narmin Ghaffari Laleh, Qinghe Zeng, Pascale Maille, Loetitia Favre, Anaïs Pujals, Christophe Klein, Céline Bazille, Lara R. Heij, Arnaud Uguen, Tom Luedde, Luca Di Tommaso, Aurélie Beaufrère, Augustin Chatain, Delphine Gastineau, Cong Trung Nguyen, Hiep Nguyen-Canh, Khuyen Nguyen Thi, Viviane Gnemmi, Rondell P. Graham, Frédéric Charlotte, Dominique Wendum, Mukul Vij, Daniela S. Allende, Federico Aucejo, Alba Diaz, Benjamin Rivière, Astrid Herrero, Katja Evert, Diego Francesco Calvisi, Jérémy Augustin, Wei Qiang Leow, Howard Ho Wai Leung, Emmanuel Boleslawski, Mohamed Rela, Arnaud François, Anthony Wing-Hung Cha, Alejandro Forner, Maria Reig, Manon Allaire, Olivier Scatton, Denis Chatelain, Camille Boulagnon-Rombi, Nathalie Sturm, Benjamin Menahem, Eric Frouin, David Tougeron, Christophe Tournigand, Emmanuelle Kempf, Haeryoung Kim, Massih Ningarhari, Sophie Michalak-Provost, Purva Gopal, Raffaele Brustia, Eric Vibert, Kornelius Schulze, Darius F. Rüther, Sören A. Weidemann, Rami Rhaiem, Jean-Michel Pawlotsky, Xuchen Zhang, Alain Luciani, Sébastien Mulé, Alexis Laurent, Giuliana Amaddeo, Hélène Regnault, Eleonora De Martin, Christine Sempoux, Pooja Navale, Maria Westerhoff, Regina Cheuk-Lam Lo, Jan Bednarsch, Annette Gouw, Catherine Guettier, Marie Lequoy, Kenichi Harada, Pimsiri Sripongpun, Poowadon Wetwittayaklang, Nicolas Loménie, Jarukit Tantipisit, Apichat Kaewdech, Jeanne Shen, Valérie Paradis, Stefano Caruso, Jakob Nikolas Kather
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Primary liver cancer arises either from hepatocytic or biliary lineage cells, giving rise to hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICCA). Combined hepatocellular- cholangiocarcinomas (cHCC-CCA) exhibit equivocal
Externí odkaz:
https://doaj.org/article/ba65186be9624b389ea48c3c89596cfd
Primary liver cancer classification from routine tumour biopsy using weakly supervised deep learning
Autor:
Aurélie Beaufrère, Nora Ouzir, Paul Emile Zafar, Astrid Laurent-Bellue, Miguel Albuquerque, Gwladys Lubuela, Jules Grégory, Catherine Guettier, Kévin Mondet, Jean-Christophe Pesquet, Valérie Paradis
Publikováno v:
JHEP Reports, Vol 6, Iss 3, Pp 101008- (2024)
Background & Aims: The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified PLCs on routine-stained biopsies using a weakly sup
Externí odkaz:
https://doaj.org/article/810dc17bccbc49af88039d6984aa7ea6
Autor:
Jérôme Boursier, Marine Roux, Charlotte Costentin, Julien Chaigneau, Céline Fournier-Poizat, Aldo Trylesinski, Clémence M. Canivet, Sophie Michalak, Brigitte Le Bail, Valérie Paradis, Pierre Bedossa, Nathalie Sturm, Victor de Ledinghen, AFEF group for the study of liver fibrosis, M118 study group, Philip N. Newsome
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Unlike for advanced liver fibrosis, the practical rules for the early non-invasive diagnosis of cirrhosis in NAFLD remain not well defined. Here, we report the derivation and validation of a stepwise diagnostic algorithm in 1568 patients wit
Externí odkaz:
https://doaj.org/article/99986da61237412caf7c819f849664b4
Autor:
Sylvaine Di Tommaso, Cyril Dourthe, Jean-William Dupuy, Nathalie Dugot-Senant, David Cappellen, Hélène Cazier, Valérie Paradis, Jean-Frédéric Blanc, Brigitte Le Bail, Charles Balabaud, Paulette Bioulac-Sage, Frédéric Saltel, Anne-Aurélie Raymond
Publikováno v:
JHEP Reports, Vol 6, Iss 2, Pp 100913- (2024)
Background & Aims: Hepatocellular adenomas (HCAs) are rare, benign, liver tumours classified at the clinicopathological, genetic, and proteomic levels. The β-catenin-activated (b-HCA) subtypes harbour several mutation types in the β-catenin gene (C
Externí odkaz:
https://doaj.org/article/88ae01c559c44a39946de35c754a7779
Autor:
Antoine Poli, Camilla Frieri, Thibaud Lefebvre, Juliette Delforge, Arienne Mirmiran, Neila Talbi, Boualem Moulouel, Marion Six, Valérie Paradis, Nathalie Parquet, Hervé Puy, Caroline Schmitt, Elisabeth Aslangul, Flore Sicre de Fontbrune, Laurent Gouya
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 37, Iss , Pp 101018- (2023)
Erythropoietic protoporphyria (EPP) is a rare metabolic disease of the heme biosynthetic pathway where an enzymatic dysfunction results in protoporphyrin IX (PPIX) accumulation in erythroid cells. The porphyrins are photo-reactive and are responsible
Externí odkaz:
https://doaj.org/article/e00f5810f3af43d2837346f6b5ed9ab7
Autor:
Morgane Mabire, Pushpa Hegde, Adel Hammoutene, Jinghong Wan, Charles Caër, Rola Al Sayegh, Mathilde Cadoux, Manon Allaire, Emmanuel Weiss, Tristan Thibault-Sogorb, Olivier Lantz, Michèle Goodhardt, Valérie Paradis, Pierre de la Grange, Hélène Gilgenkrantz, Sophie Lotersztajn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Liver cirrhosis is characterised by extensive fibrosis of the liver, and understanding the underpinning immunological processes is important in designing intervention. Here authors show that Mucosal-Associated Invariant T cells are instrumental to co
Externí odkaz:
https://doaj.org/article/49d8dca78ad94f9fac7e66da26a40cc1
A new NRF2 activator for the treatment of human metabolic dysfunction-associated fatty liver disease
Autor:
Adel Hammoutene, Samira Laouirem, Miguel Albuquerque, Nathalie Colnot, Angélique Brzustowski, Dominique Valla, Nicolas Provost, Philippe Delerive, Valérie Paradis
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100845- (2023)
Background & Aims: Oxidative stress triggers metabolic-associated fatty liver disease (MAFLD) and fibrosis. Previous animal studies demonstrated that the transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2), the master regulator of
Externí odkaz:
https://doaj.org/article/797f996f516a4f5ebd96f64fabc15d6d