Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Valérie Nicolas"'
Autor:
Hoai-Nam Truong, Carine Fournier, Siham Hichami, Léna Dole, Fanny Leroy, David Wendehenne, Valérie Nicolas-Francès, Angélique Besson-Bard
Publikováno v:
Plant Stress, Vol 12, Iss , Pp 100488- (2024)
Iron (Fe) is an essential micronutrient for most organisms that is, however, poorly bioavailable in the soil. Acquiring this element is therefore a major issue for both plants and microorganisms. Bacteria acquire Fe by secreting siderophores that che
Externí odkaz:
https://doaj.org/article/5dbe196afab74e64a1cc4fa6b205d580
Autor:
Sameh Obeid, Eloisa Berbel-Manaia, Valérie Nicolas, Indira Dennemont, Julien Barbier, Jean-Christophe Cintrat, Daniel Gillet, Philippe M. Loiseau, Sébastien Pomel
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108144- (2023)
Summary: Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly to avoid the emergence of drug resistance, are needed. The p
Externí odkaz:
https://doaj.org/article/dbcda9f2fa5048c280c47e5708a19e5b
Autor:
Miora Rakotoarisoa, Borislav Angelov, Markus Drechsler, Valérie Nicolas, Thomas Bizien, Yulia E. Gorshkova, Yuru Deng, Angelina Angelova
Publikováno v:
Smart Materials in Medicine, Vol 3, Iss , Pp 274-288 (2022)
We develop multidrug-loaded cubosome and spongosome lipid nanoparticles for targeting of endoplasmic reticulum stress as a potential emerging therapeutic strategy against neuronal degeneration. The multicompartment organization of the liquid crystall
Externí odkaz:
https://doaj.org/article/51556600705043c0a87265adb60ec440
Autor:
Romain Brusini, Natalie Lan Linh Tran, Catherine Cailleau, Valérie Domergue, Valérie Nicolas, Flavio Dormont, Serge Calet, Caroline Cajot, Albin Jouran, Sinda Lepetre-Mouelhi, Julie Laloy, Patrick Couvreur, Mariana Varna
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1790 (2023)
Reperfusion injuries after a period of cardiac ischemia are known to lead to pathological modifications or even death. Among the different therapeutic options proposed, adenosine, a small molecule with platelet anti-aggregate and anti-inflammatory pr
Externí odkaz:
https://doaj.org/article/51b5c206bd4e446d9ced361c561529a2
Autor:
Valérie Nicolas-Francès, Jordan Rossi, Claire Rosnoblet, Carole Pichereaux, Siham Hichami, Jeremy Astier, Agnès Klinguer, David Wendehenne, Angélique Besson-Bard
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Tyrosine-specific protein tyrosine phosphatases (Tyr-specific PTPases) are key signaling enzymes catalyzing the removal of the phosphate group from phosphorylated tyrosine residues on target proteins. This post-translational modification notably allo
Externí odkaz:
https://doaj.org/article/0daf20613ef540b69695c96fae899ca9
Autor:
Pierre-Alexandre Lacotte, Alexis Simons, Sylvie Bouttier, Jeanne Malet-Villemagne, Valérie Nicolas, Claire Janoir
Publikováno v:
Microorganisms, Vol 10, Iss 6, p 1082 (2022)
Clostridioides difficile is responsible for post-antibiotic diarrhea and most of the pseudomembranous colitis cases. Multiple recurrences, one of the major challenges faced in C. difficile infection (CDI) management, can be considered as chronic infe
Externí odkaz:
https://doaj.org/article/4bdd76b7f4204bf7bc7c7ffbb100f133
Autor:
Dawei Liu, Félix Peyre, Yahir Alberto Loissell-Baltazar, Delphine Courilleau, Sandra Lacas-Gervais, Valérie Nicolas, Eric Jacquet, Svetlana Dokudovskaya, Frédéric Taran, Jean-Christophe Cintrat, Catherine Brenner
Publikováno v:
Cells, Vol 11, Iss 3, p 474 (2022)
Improvement of anticancer treatments is associated with increased survival of cancer patients at risk of cardiac disease. Therefore, there is an urgent need for new therapeutic molecules capable of preventing acute and long-term cardiotoxicity. Here,
Externí odkaz:
https://doaj.org/article/81e185c893984ddf9d0fd96e88019aa0
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008396 (2020)
The parasitophorous vacuoles (PVs) that insulate Leishmania spp. in host macrophages are vacuolar compartments wherein promastigote forms differentiate into amastigote that are the replicative form of the parasite and are also more resistant to host
Externí odkaz:
https://doaj.org/article/6b2edfbc55354b6c8732e3b605a90013
Autor:
Frauke Beilstein, Gary H Cohen, Roselyn J Eisenberg, Valérie Nicolas, Audrey Esclatine, David Pasdeloup
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008209 (2019)
The processes of cell attachment and membrane fusion of Herpes Simplex Virus 1 involve many different envelope glycoproteins. Viral proteins gC and gD bind to cellular receptors. Upon binding, gD activates the gH/gL complex which in turn activates gB
Externí odkaz:
https://doaj.org/article/8ca54bb9a6d847638a0d13582cefddd9
Autor:
Amandine Gendron, Natalie Lan Linh Tran, Julie Laloy, Romain Brusini, Aurélie Rachet, Frédéric Gobeaux, Valérie Nicolas, Pierre Chaminade, Sonia Abreu, Didier Desmaële, Mariana Varna
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 91 (2021)
Cyclosporin A (CsA) is a molecule with well-known immunosuppressive properties. As it also acts on the opening of mitochondrial permeability transition pore (mPTP), CsA has been evaluated for ischemic heart diseases (IHD). However, its distribution t
Externí odkaz:
https://doaj.org/article/422435c66d834441a3dc418daa585a1f