Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Valérie Mongrain"'
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Sleep disturbances are a common comorbidity to most neurodevelopmental disorders and tend to worsen disease symptomatology. It is thus crucial to understand mechanisms underlying sleep disturbances to improve patients’ quality o
Externí odkaz:
https://doaj.org/article/64f2f09b696b4e3babfeac980bd2855c
Autor:
Audrey Hector, Chloé Provost, Benoît Delignat-Lavaud, Khadija Bouamira, Chahinez-Anissa Menaouar, Valérie Mongrain, Jonathan Brouillette
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Soluble amyloid-beta oligomers (Aβo) begin to accumulate in the human brain one to two decades before a clinical diagnosis of Alzheimer’s disease (AD). The literature supports that soluble Aβo are implicated in synapse and neu
Externí odkaz:
https://doaj.org/article/2f6417eed4e74d12ba15182bc635bb6b
Autor:
Maria Neus Ballester Roig, Tanya Leduc, Julien Dufort-Gervais, Yousra Maghmoul, Olivier Tastet, Valérie Mongrain
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-18 (2023)
Abstract Background Rhynchophylline (RHY) is an alkaloid component of Uncaria, which are plants extensively used in traditional Asian medicines. Uncaria treatments increase sleep time and quality in humans, and RHY induces sleep in rats. However, lik
Externí odkaz:
https://doaj.org/article/b54f79bc27234e53aae0a550beb8b401
Publikováno v:
Clocks & Sleep, Vol 3, Iss 2, Pp 312-341 (2021)
Uncaria rhynchophylla is a plant highly used in the traditional Chinese and Japanese medicines. It has numerous health benefits, which are often attributed to its alkaloid components. Recent studies in humans show that drugs containing Uncaria amelio
Externí odkaz:
https://doaj.org/article/0e7632e55f72421c831ee513727901b1
Autor:
Valérie Mongrain, Nicolaas H. van Doesburg, Françoise Rypens, Catherine Fallet-Bianco, Justine Maassen, Julien Dufort-Gervais, Lucie Côté, Philippe Major
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Disease severity is tremendously variable in tuberous sclerosis complex (TSC). In contrast with the detailed guidelines available for TSC diagnosis and management, clinical practice lacks adequate tools to evaluate the prognosis,
Externí odkaz:
https://doaj.org/article/8f5d64de8ae14090bee287a7a42bce1b
Publikováno v:
Neurobiology of Sleep and Circadian Rhythms, Vol 11, Iss , Pp 100068- (2021)
Sleep is a vital part of our lives as it is required to maintain health and optimal cognition. In humans, sex differences are relatively well-established for many sleep phenotypes. However, precise differences in sleep phenotypes between male and fem
Externí odkaz:
https://doaj.org/article/31ae2d30d5d94a599e5d43baf83bbfe5
Publikováno v:
Molecular Brain, Vol 11, Iss 1, Pp 1-11 (2018)
Abstract Sleep disorders are comorbid with most psychiatric disorders, but the link between these is not well understood. Neuroligin-2 (NLGN2) is a cell adhesion molecule that plays roles in synapse formation and neurotransmission. Moreover, NLGN2 ha
Externí odkaz:
https://doaj.org/article/9b13834d5b3741109d0fbe4bb5f18c44
Autor:
Bong Soo Seok, Feng Cao, Erika Bélanger-Nelson, Chloé Provost, Steve Gibbs, Zhengping Jia, Valérie Mongrain
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-1 (2019)
Correction to: Molecular Brain (2018) 11:52 https://doi.org/10.1186/s13041-018-0394-3 Following publication of the original article [1], the authors reported that the article was mistakenly submitted with the omission of two authors: Feng Cao and Zhe
Externí odkaz:
https://doaj.org/article/bee614a2b9dc4a8d938da1fe6a8bd5b2
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59808 (2013)
Many aspects of the immune system, including circulating cytokine levels as well as counts and function of various immune cell types, present circadian rhythms. Notably, the mortality rate of animals subjected to high doses of lipopolysaccharide is d
Externí odkaz:
https://doaj.org/article/788904b9f2d94e26a341c9be22fc701e
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26622 (2011)
We have previously demonstrated that clock genes contribute to the homeostatic aspect of sleep regulation. Indeed, mutations in some clock genes modify the markers of sleep homeostasis and an increase in homeostatic sleep drive alters clock gene expr
Externí odkaz:
https://doaj.org/article/5c1ded53fbab46529e5729f1ff5e702d