Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Valérie M. Renault"'
Autor:
Sabrina Sacconi, Liudmyla Lototska, Laurent Schaeffer, Jérôme D. Robin, Camille Laberthonnière, Mélanie Pousse, Eric Gilson, Jean Luc Thomas, Waiian Leong, Jing Ye, Frédérique Magdinier, Serge Bauwens, Valérie M. Renault, Florent Tessier, Olivier Croce, Han Peng, Maria‐Sol Jacome Burbano
Publikováno v:
Aging Cell
Aging Cell, Wiley Open Access, 2020, 19 (3), ⟨10.1111/acel.13097⟩
Aging Cell, 2020, 19 (3), ⟨10.1111/acel.13097⟩
Aging Cell, Wiley Open Access, 2020, 19 (3), ⟨10.1111/acel.13097⟩
Aging Cell, 2020, 19 (3), ⟨10.1111/acel.13097⟩
Telomere shortening follows a developmentally regulated process that leads to replicative senescence of dividing cells. However, whether telomere changes are involved in postmitotic cell function and aging remains elusive. In this study, we discovere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9910e6423df001a9241178d92e04d4
https://hal-amu.archives-ouvertes.fr/hal-03080383
https://hal-amu.archives-ouvertes.fr/hal-03080383
Autor:
Nicolas Soubeiran, François Ghiringhelli, Pasquale Zizza, Eric Gilson, Charlene Iltis, Annamaria Biroccio, Fabrice Allain, Marina Shkreli, Romy Collet, Ludovic Cervera, Eric Vivier, Sabrina Pisano, Balázs Győrffy, Carlo Leonetti, Martin Rey-Millet, Julien Cherfils-Vicini, Olivier Croce, Nori Sadouni, Valérie M. Renault
Publikováno v:
EMBO JOURNAL
EMBO JOURNAL, 2019, 38 (11), ⟨10.15252/embj.2018100012⟩
EMBO Journal
EMBO Journal, EMBO Press, 2019, 38 (11), ⟨10.15252/embj.2018100012⟩
EMBO J
EMBO Journal, 2019, 38 (11), ⟨10.15252/embj.2018100012⟩
EMBO JOURNAL, 2019, 38 (11), ⟨10.15252/embj.2018100012⟩
EMBO Journal
EMBO Journal, EMBO Press, 2019, 38 (11), ⟨10.15252/embj.2018100012⟩
EMBO J
EMBO Journal, 2019, 38 (11), ⟨10.15252/embj.2018100012⟩
International audience; Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells with strong immunosuppressive activity that promote tumor growth. In this study, we describe a mechanism by which cancer cells control MDSCs in human cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8b5e3e52bf0cbaf3219495c6ec20bb
https://hal.archives-ouvertes.fr/hal-02359442
https://hal.archives-ouvertes.fr/hal-02359442
Publikováno v:
Nature Reviews Genetics. 15:491-503
Telomeres protect chromosome ends from degradation and inappropriate DNA damage response activation through their association with specific factors. Interestingly, these telomeric factors are able to localize outside telomeric regions, where they can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c33da7cae482023fa9836dd54c0a1a
https://doi.org/10.1038/nrg3743
https://doi.org/10.1038/nrg3743
Publikováno v:
Aging (Albany NY)
In adult mammals, neural stem cells (NSCs) generate new neurons that are important for specific types of learning and memory. Controlling adult NSC number and function is fundamental for preserving the stem cell pool and ensuring proper levels of neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a083e0fa1f2843120621d8c65ead7b
https://doi.org/10.18632/aging.100285
https://doi.org/10.18632/aging.100285
Autor:
Dervis A. Salih, Saul A. Villeda, Valérie M. Renault, Alexander A. Morgan, Jamie O. Brett, Nicholas C. Denko, Ashley E. Webb, Victoria A. Rafalski, Pramod Thekkat, Theo D. Palmer, Camille Guillerey, Atul J. Butte, Anne Brunet
Publikováno v:
Cell Stem Cell. 5(5):527-539
SummaryIn the nervous system, neural stem cells (NSCs) are necessary for the generation of new neurons and for cognitive function. Here we show that FoxO3, a member of a transcription factor family known to extend lifespan in invertebrates, regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff5b8b5ad9c9485d860b66572789080
Autor:
Caroline Schluth-Bolard, Pascal Pineau, Michelina Plateroti, Marina Shkreli, Jing Ye, Thomas Simonet, Anne Dejean, Steven E. Artandi, Irmina Diala, Maria Sirakov, Frédérique Magdinier, Serge Bauwens, Jinkuk Choi, Valérie M. Renault, Abdelnnadir Djerbi, Nicole Wagner, Eric Gilson
Publikováno v:
EMBO Reports
EMBO Reports, 2013, 14 (4), pp.356-363. ⟨10.1038/embor.2013.16⟩
EMBO Reports, EMBO Press, 2013, 14 (4), pp.356-363. ⟨10.1038/embor.2013.16⟩
EMBO Reports, 2013, 14 (4), pp.356-363. ⟨10.1038/embor.2013.16⟩
EMBO Reports, EMBO Press, 2013, 14 (4), pp.356-363. ⟨10.1038/embor.2013.16⟩
International audience; The DNA-binding protein TRF2 is essential for telomere protection and chromosome stability in mammals. We show here that TRF2 expression is activated by the Wnt/b-catenin signalling pathway in human cancer and normal cells as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657df203a3e775e2407b0cfce5eb30f1
https://hal-amu.archives-ouvertes.fr/hal-01663630/file/356.full.pdf
https://hal-amu.archives-ouvertes.fr/hal-01663630/file/356.full.pdf
Autor:
Linheng Li, Miao Chia Lo, Julien Sage, Patrick Viatour, John M. Perry, Ruoying Tan, Joseph R. Biggs, Alessandra Sacco, Valérie M. Renault, Anne Brunet, Steven Schaffert, Michael L. Cleary, Caifu Chen, Helen M. Blau, Christopher P. Arnold, Baiyu Zhou, Tim C. P. Somervaille, Dong-Er Zhang, Regis Doyonnas, Si Biao Yue, Chang-Zheng Chen
Emerging evidence suggests that microRNAs (miRNAs), an abundant class of ∼22-nucleotide small regulatory RNAs, play key roles in controlling the post-transcriptional genetic programs in stem and progenitor cells. Here we systematically examined miR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f08f413feca448501733be2f0f032c
https://europepmc.org/articles/PMC3083097/
https://europepmc.org/articles/PMC3083097/
Autor:
Ophelia S. Venturelli, Colleen A. Brady, Jamie L. White, Valérie M. Renault, Laura D. Attardi, P R Oskoui, Evan E. Santo, Hannes Vogel, Pramod Thekkat, Zhenyu Xuan, Michael Q. Zhang, K L Hoang, D Kenzelmann Broz, Anne Brunet, Thomas M. Johnson
Publikováno v:
Oncogene
Oncogene, 30(29), 3207-3221. Nature Publishing Group
Oncogene, 30(29), 3207-3221. Nature Publishing Group
FoxO transcription factors have a conserved role in longevity, and act as tissue-specific tumor suppressors in mammals. Several nodes of interaction have been identified between FoxO transcription factors and p53, a major tumor suppressor in humans a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c422535813c97e1406527ea76b78be4
https://pubmed.ncbi.nlm.nih.gov/21423206
https://pubmed.ncbi.nlm.nih.gov/21423206
Autor:
Yasmine Hadjal, Ola Hadadeh, Didier Nègre, Valérie M. Renault, Emilie Barruet, Irène Juhan-Vague, Roselyne Tournaire, Bernard Binétruy, Denis Bernot, Marie-Christine Alessi, Franck Peiretti
Publikováno v:
Stem Cells and Development
Stem Cells and Development, 2011, 20 (7), pp.1233-1246. ⟨10.1089/scd.2010.0213⟩
Stem Cells and Development, 2011, 20 (7), pp.1233-46. ⟨10.1089/scd.2010.0213⟩
Stem Cells and Development, 2011, 20 (7), pp.1233-1246. ⟨10.1089/scd.2010.0213⟩
Stem Cells and Development, 2011, 20 (7), pp.1233-46. ⟨10.1089/scd.2010.0213⟩
International audience; Embryonic stem (ES) cells differentiate in vitro into all cell lineages. We previously found that the p38 mitogen activated kinase (p38MAPK) pathway controls the commitment of ES cells toward either cardiomyogenesis (p38 on) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb159b4b52862649b48001acb469c6b
https://pubmed.ncbi.nlm.nih.gov/20954847
https://pubmed.ncbi.nlm.nih.gov/20954847
Publikováno v:
Seminars in celldevelopmental biology. 16(4-5)
The Notch signaling pathway is an evolutionarily conserved pathway that is critical for tissue morphogenesis during development, but is also involved in tissue maintenance and repair in the adult. In skeletal muscle, regulation of Notch signaling is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fca93732137a26dc5114a91178dbda9
https://pubmed.ncbi.nlm.nih.gov/16087370
https://pubmed.ncbi.nlm.nih.gov/16087370