Výsledky vyhledávání - "Valérie Frère"

A Peptide Fragment of Human DNA Topoisomerase II α Forms a Stable Coiled-coil Structure in Solution

Autor: Monique Monnot, Serge Fermandjian, Valérie Frère, Frédéric Sourgen, Frédéric Troalen

Publikováno v: Journal of Biological Chemistry. 270:17502-17507

Results are presented on a peptide fragment (1013-1056) from human DNA topoisomerase II alpha. This was selected using the procedure of Lupas et al. (Lupas, A., Van Dyke, M., and Stock, J. (1991) Science 252, 1162-1164) for its potential to adopt a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e9b6a95c6648d3409b75b930ded466
https://doi.org/10.1074/jbc.270.29.17502

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Peptide fragments of DNA topoisomerase II with helix-forming and coiled-coil-forming properties act as inhibitors of the enzyme

Autor: Serge Fermandjian, Denis Scala, Daniel Krebs, Valérie Frère‐Gallois, Frédéric Troalen

Publikováno v: European journal of biochemistry. 249(1)

We have previously shown that a synthetic peptide (dL) consisting of amino acids 1013-1056 of human alpha topoisomerase II adopted an alpha-helix structure and formed a stable dimer coiled-coil in solution [Frère, V., Sourgen. F., Monnot, M., Troale

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928b1c083d7c2d85cc43aea961d70e10
https://pubmed.ncbi.nlm.nih.gov/9363765

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A synthetic peptide from the human immunodeficiency virus type-1 integrase exhibits coiled-coil properties and interferes with the in vitro integration activity of the enzyme. Correlated biochemical and spectroscopic results

Autor: Valérie Frère, Richard G. Maroun, Frédéric Sourgen, Serge Fermandjian, Mohammed Bouziane, Christian Auclair, Frédéric Troalen

Publikováno v: European journal of biochemistry. 240(3)

Integration of the human immunodeficiency virus (HIV-1) DNA into the host genome is catalysed by a virus-encoded protein integrase. Here, we report some of the structural and functional properties of two synthetic peptides: integraw(147 - 175)-peptid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0f5143be71522dfecf16f7b5ddb5fd
https://pubmed.ncbi.nlm.nih.gov/8856082

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