Výsledky vyhledávání - "Valérie Fitton-Ouhabi"

Akademický článek

Two missense mutations, E123Q and K151E, identified in the ERG11 allele of an azole-resistant isolate of Candida kefyr recovered from a stem cell transplant patient for acute myeloid leukemia

Autor: Célia Couzigou, Frédéric Gabriel, Nicolas Biteau, Valérie Fitton-Ouhabi, Thierry Noël, Isabelle Accoceberry

Publikováno v: Medical Mycology Case Reports, Vol 5, Iss C, Pp 12-15 (2014)

We report on the first cloning and nucleotide sequencing of an ERG11 allele from a clinical isolate of Candida kefyr cross-resistant to azole antifungals. It was recovered from a stem cell transplant patient, in an oncohematology unit exhibiting unex

Externí odkaz: https://doaj.org/article/018970bd9cbf44ae89b8a6f0dbd63709

Zobrazit plný text záznamu

Challenging SNP impact on caspofungin resistance by full-lengthFKS1allele replacement inCandida lusitaniae

Autor: Thierry Noël, Isabelle Accoceberry, Nicolas Biteau, Valérie Fitton-Ouhabi, Célia Couzigou

Publikováno v: Journal of Antimicrobial Chemotherapy. 74:618-624

Objectives A strain of the opportunistic pathogenic yeast Candida lusitaniae was genetically engineered for full-length replacement of the FKS1 gene encoding the target of echinocandin antifungals in order to assess the impact of FKS mutations on ech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffe3e688a14adc1bfacd6f725e35c12
https://doi.org/10.1093/jac/dky475

Zobrazit plný text záznamu

Genome Sequence of the Yeast Clavispora lusitaniae Type Strain CBS 6936

Autor: Christophe Klopp, Isabelle Accoceberry, Nicolas Biteau, Pascal Durrens, Karine Dementhon, Valérie Fitton-Ouhabi, Thierry Noël, David James Sherman

Publikováno v: Genome Announcements
Genome Announcements 31 (5), e00724-17. (2017)
Genome Announcements, American Society for Microbiology, 2017, 5 (31), ⟨10.1128/genomeA.00724-17⟩
Genome Announcements, American Society for Microbiology, 2017, 5 (31), pp.e00724-17. ⟨10.1128/genomeA.00724-17⟩
Genome Announcements, 2017, 5 (31), pp.e00724-17. ⟨10.1128/genomeA.00724-17⟩

Clavispora lusitaniae , an environmental saprophytic yeast belonging to the CTG clade of Candida , can behave occasionally as an opportunistic pathogen in humans. We report here the genome sequence of the type strain CBS 6936. Comparison with sequenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e5f963c7a1f7929ce1898e5d1b303b
http://europepmc.org/articles/PMC5543641

Zobrazit plný text záznamu

A CTG Clade Candida Yeast Genetically Engineered for the Genotype-Phenotype Characterization of Azole Antifungal Resistance in Human-Pathogenic Yeasts

Autor: Thierry Noël, Pauline Chevrel, Amandine Rougeron, Isabelle Accoceberry, Nicolas Biteau, Valérie Fitton-Ouhabi

Publikováno v: Antimicrobial agents and chemotherapy. 62(1)

A strain of the opportunistic pathogenic yeast Candida lusitaniae was genetically modified for use as a cellular model for assessing by allele replacement the impact of lanosterol C14α-demethylase ERG11 mutations on azole resistance. Candida lusitan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cb7667e845c265dc2aee65ab842a3a
https://pubmed.ncbi.nlm.nih.gov/29038279

Zobrazit plný text záznamu

Construction d’une souche de Candida lusitaniae génétiquement modifiée pour l’étude des mutations de résistance aux échinocandines

Autor: Thierry Noël, Célia Couzigou, Isabelle Accoceberry, Valérie Fitton-Ouhabi

Publikováno v: Journal de Mycologie Médicale. 25:230-231

Introduction Les echinocandines alterent la synthese de la paroi fongique en inhibant la β-(1-3)-D-glucane synthetase, codee par les genes FKS . Des mutations dans deux regions « Hot Spot » (HS) tres conservees des genes FKS ont ete decrites dans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e825277fd47a298044fb58fe6a32f9ca
https://doi.org/10.1016/j.mycmed.2015.06.032

Zobrazit plný text záznamu

Nouvelles approches pour la caractérisation des mutations de résistance aux antifongiques

Autor: Pauline Chevrel, Célia Couzigou, Isabelle Accoceberry, Valérie Fitton-Ouhabi, Amandine Rougeron, Thierry Noël, Frédéric Gabriel

Publikováno v: Journal de Mycologie Médicale. 25:222-223

Les mecanismes de resistance aux antifongiques azoles et aux echinocandines reposent en grande partie sur des mutations des genes codant la cible. Chez les levures du genre Candida, il s’agit du gene codant la proteine Erg11, la lanosterol demethyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::125bb2442774ef785b8bb3dea7802ffe
https://doi.org/10.1016/j.mycmed.2015.06.015

Zobrazit plný text záznamu

Cabanillasin, a new antifungal metabolite, produced by entomopathogenic Xenorhabdus cabanillasii JM26

Autor: Valérie Fitton-Ouhabi, Jessica Houard, André Aumelas, Philippe Villain-Guillot, Maxime Gualtieri, Thierry Noël, Sylvie Pages, Alain Givaudan

Publikováno v: Journal of Antibiotics
Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2013, 66 (10), pp.617-20. ⟨10.1038/ja.2013.58⟩
Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2013, 66, pp.617-20. ⟨10.1038/ja.2013.58⟩

International audience; Since the early 1980s, fungi have emerged as a major cause of human disease. Fungal infections are associated with high levels of morbidity and mortality, and are now recognized as an important public health problem. Gram-nega

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5db28b32fbe9a59f188cfdd9a5b0f61
https://hal.archives-ouvertes.fr/hal-01101425

Zobrazit plný text záznamu

A disseminated infection with the antifungal-multiresistant teleomorphic fungus Neocosmospora vasinfecta in a patient with acute B-lymphoblastic leukemia

Autor: Olivier Albert, Frédéric Gabriel, Thierry Noël, Mahussi D’Almeida, Isabelle Accoceberry, Valérie Fitton-Ouhabi

Publikováno v: Medical Mycology
Medical Mycology, 2013, 2, pp.44-7
Medical Mycology, Oxford University Press, 2013, 2, pp.44-7

International audience; We report on a fatal invasive infection due to the ascomycetous fungus Neocosmospora vasinfecta, in a 20-year-old European patient suffering from an acute lymphoblastic leukemia. The infection could not be controlled by a bith

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ea0805ae0bb1f69af9446e562b79b4
https://pubmed.ncbi.nlm.nih.gov/24432214

Zobrazit plný text záznamu

Nonsense and missense mutations in FCY2 and FCY1 genes are responsible for flucytosine resistance and flucytosine-fluconazole cross-resistance in clinical isolates of Candida lusitaniae

Autor: Valérie Fitton-Ouhabi, Martine Florent, Thierry Noël, Gwenaël Ruprich-Robert, Nicolas Papon, Bruno Da Silva, Christiane Chastin, Florence Chapeland-Leclerc

Publikováno v: Antimicrobial agents and chemotherapy. 53(7)

The aim of this work was to elucidate the molecular mechanisms of flucytosine (5FC) resistance and 5FC/fluconazole (FLC) cross-resistance in 11 genetically and epidemiologically unrelated clinical isolates of Candida lusitaniae . We first showed that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c9502c2aa8b58d2fd05b88a8d82d45
https://pubmed.ncbi.nlm.nih.gov/19414575

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání