Objective Identification of Intermediate Lesions Inducing Myocardial Ischemia Using Sequential Intracoronary Pressure and Flow Measurements

Autor: Valérie E. Stegehuis, Gilbert W. M. Wijntjens, Sukhjinder S. Nijjer, Guus A. de Waard, Tim P. van de Hoef, Sayan Sen, Ricardo Petraco, Mauro Echavarría‐Pinto, Martijn Meuwissen, Ibrahim Danad, Paul Knaapen, Javier Escaned, Justin E. Davies, Niels van Royen, Jan J. Piek

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 13 (2020)

Background Although ischemic heart disease has a complex and multilevel origin, the diagnostic approach is mainly focused on focal obstructive disease as assessed by pressure‐derived indexes. The prognostic relevance of coronary flow over coronary

Externí odkaz: https://doaj.org/article/51a883b4b0854afd87a07030351634a1

Impact of core laboratory assessment on treatment decisions and clinical outcomes using combined fractional flow reserve and coronary flow reserve measurements - DEFINE-FLOW core laboratory sub-study

Autor: Tim P. van de Hoef, Valérie E. Stegehuis, Maribel I. Madera-Cambero, Niels van Royen, Nina W. van der Hoeven, Guus A. de Waard, Martijn Meuwissen, Evald H. Christiansen, Ashkan Eftekhari, Giampaolo Niccoli, Tim Lockie, Hitoshi Matsuo, Masafumi Nakayama, Tsunekazu Kakuta, Nobuhiro Tanaka, Lorena Casadonte, Jos A.E. Spaan, Maria Siebes, Jan G.P. Tijssen, Javier Escaned, Jan J. Piek

Publikováno v: International Journal of Cardiology, 377, pp. 9-16
van de Hoef, T P, Stegehuis, V E, Madera-Cambero, M I, van Royen, N, van der Hoeven, N W, de Waard, G A, Meuwissen, M, Christiansen, E H, Eftekhari, A, Niccoli, G, Lockie, T, Matsuo, H, Nakayama, M, Kakuta, T, Tanaka, N, Casadonte, L, Spaan, J A E, Siebes, M, Tijssen, J G P, Escaned, J & Piek, J J 2023, ' Impact of core laboratory assessment on treatment decisions and clinical outcomes using combined fractional flow reserve and coronary flow reserve measurements – DEFINE-FLOW core laboratory sub-study ', International Journal of Cardiology, vol. 377, pp. 9-16 . https://doi.org/10.1016/j.ijcard.2023.01.009
van de Hoef, T P, Stegehuis, V E, Madera-Cambero, M I, van Royen, N, van der Hoeven, N W, de Waard, G A, Meuwissen, M, Christiansen, E H, Eftekhari, A, Niccoli, G, Lockie, T, Matsuo, H, Nakayama, M, Kakuta, T, Tanaka, N, Casadonte, L, Spaan, J A E, Siebes, M, Tijssen, J G P, Escaned, J & Piek, J J 2023, ' Impact of core laboratory assessment on treatment decisions and clinical outcomes using combined fractional flow reserve and coronary flow reserve measurements-DEFINE-FLOW core laboratory sub-study ', International Journal of Cardiology, vol. 377, pp. 9-16 . https://doi.org/10.1016/j.ijcard.2023.01.009
International journal of cardiology, 377, 9-16. Elsevier Ireland Ltd
International Journal of Cardiology, 377, 9-16
International Journal of Cardiology, 377, 9-16. Elsevier Ireland Ltd

OBJECTIVE: The role of combined FFR/CFR measurements in decision-making on coronary revascularization remains unclear. DEFINE-FLOW prospectively assessed the relationship of FFR/CFR agreement with 2-year major adverse cardiac event (MACE) and target

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f98514108fd7b4771228c5899511e7
https://doi.org/10.1016/j.ijcard.2023.01.009

Distal Evaluation of Functional performance with Intravascular sensors to assess the Narrowing Effect—combined pressure and Doppler FLOW velocity measurements (DEFINE-FLOW) trial: Rationale and trial design

Autor: Lorena Casadonte, Maria Siebes, Jos A. E. Spaan, Jan J. Piek, Valérie E. Stegehuis, Tim P. van de Hoef, K. Lance Gould, Richard L. Kirkeeide, Nils P. Johnson, Gilbert W. M. Wijntjens

Publikováno v: American heart journal, 222, 139-146. Mosby Inc.

Background: It remains uncertain if invasive coronary physiology beyond fractional flow reserve (FFR) can refine lesion selection for revascularization or provide additional prognostic value. Coronary flow reserve (CFR) equals the ratio of hyperemic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14cf49fe2b2f87496d5490e0b5471bc
http://www.scopus.com/inward/record.url?scp=85079395744&partnerID=8YFLogxK

Contribution of Age-Related Microvascular Dysfunction to Abnormal Coronary

Autor: Tim P. van de Hoef, Martijn Meuwissen, Valérie E. Stegehuis, Mauro Echavarria-Pinto, Jan J. Piek, Javier Escaned

Publikováno v: JACC: Cardiovascular Interventions. 13:20-29

Objectives This study sought to investigate the contribution of age-related microcirculatory dysfunction to abnormal coronary hemodynamics in patients with coronary atherosclerosis. Background Impairment in myocardial blood supply in patients with co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5e69d1a430f57c99a82e3bf8ddf7d0c
https://doi.org/10.1016/j.jcin.2019.08.052

Evaluation of traditional and non-traditional risk factors as predictive values for a positive acetylcholine provocation test in patients with ischemia and no obstructive coronary artery disease

Autor: Marcel A.M. Beijk, Valérie E. Stegehuis, E Beijderwellen, Rutger Feenstra, Jan J. Piek, M.E Wittekoek

Publikováno v: European Heart Journal. 41

Background Coronary vasomotor function disorders, such as microvascular angina (MVA) and vasospastic angina (VSA) can be diagnosed in three quarters of all patients with signs and symptoms of ischemia and no obstructive coronary artery disease (INOCA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::587f8a033aa04a353e728734514e90e7
https://doi.org/10.1093/ehjci/ehaa946.2490