Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Valérie Demais"'
Autor:
Jelena Scekic-Zahirovic, Inmaculada Sanjuan-Ruiz, Vanessa Kan, Salim Megat, Pierre De Rossi, Stéphane Dieterlé, Raphaelle Cassel, Marguerite Jamet, Pascal Kessler, Diana Wiesner, Laura Tzeplaeff, Valérie Demais, Sonu Sahadevan, Katharina M. Hembach, Hans-Peter Muller, Gina Picchiarelli, Nibha Mishra, Stefano Antonucci, Sylvie Dirrig-Grosch, Jan Kassubek, Volker Rasche, Albert Ludolph, Anne-Laurence Boutillier, Francesco Roselli, Magdalini Polymenidou, Clotilde Lagier-Tourenne, Sabine Liebscher, Luc Dupuis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Mutations in the RNA binding protein FUS are associated with ALS. Here the authors show that in FUS knock-in mice there is a progressive increase in neuronal activity in the frontal cortex which is associated with altered synaptic gene expression.
Externí odkaz:
https://doaj.org/article/81d53965ba1c4f5cbe4fa11bc13113fd
Autor:
Amélie Barthelemy, Valérie Demais, Izabela-Cristina Stancu, Eugeniu Vasile, Tom Houben, Michael Reber, Valentina Pallottini, Martine Perraut, Sophie Reibel, Frank W. Pfrieger
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105469- (2021)
Niemann-Pick type C disease is a rare and fatal lysosomal storage disorder presenting severe neurovisceral symptoms. Disease-causing mutations in genes encoding either NPC1 or NPC2 protein provoke accumulation of cholesterol and other lipids in speci
Externí odkaz:
https://doaj.org/article/403658d39f4344499eda03063ddd8fad
Autor:
Emeline Tanguy, Tamou Thahouly, Cathy Royer, Valérie Demais, Stéphane Gasman, Sylvette Chasserot-Golaz, Nicolas Vitale
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100464- (2021)
Summary: The glycerophospholipid phosphatidic acid (PA) is a key player in regulated exocytosis, but little is known about its localization at the plasma membrane. Here, we provide a protocol for precisely determining the spatial distribution of PA a
Externí odkaz:
https://doaj.org/article/3bbd5144a38744fe9af8320d9c998599
Autor:
Kevin Dorgans, Valérie Demais, Yannick Bailly, Bernard Poulain, Philippe Isope, Frédéric Doussau
Publikováno v:
eLife, Vol 8 (2019)
Information processing by cerebellar molecular layer interneurons (MLIs) plays a crucial role in motor behavior. MLI recruitment is tightly controlled by the profile of short-term plasticity (STP) at granule cell (GC)-MLI synapses. While GCs are the
Externí odkaz:
https://doaj.org/article/925339f81df0457cb06e9b172e515c7b
Autor:
Catherine A. Royer, Tamou Thahouly, Emeline Tanguy, Sylvette Chasserot-Golaz, Valérie Demais, Stéphane Gasman, Nicolas Vitale
Publikováno v:
STAR Protocols
STAR Protocols, Elsevier, 2021, 2 (2), ⟨10.1016/j.xpro.2021.100464⟩
STAR Protocols, 2021, 2 (2), ⟨10.1016/j.xpro.2021.100464⟩
STAR Protocols, Vol 2, Iss 2, Pp 100464-(2021)
STAR Protocols, Elsevier, 2021, 2 (2), ⟨10.1016/j.xpro.2021.100464⟩
STAR Protocols, 2021, 2 (2), ⟨10.1016/j.xpro.2021.100464⟩
STAR Protocols, Vol 2, Iss 2, Pp 100464-(2021)
Summary The glycerophospholipid phosphatidic acid (PA) is a key player in regulated exocytosis, but little is known about its localization at the plasma membrane. Here, we provide a protocol for precisely determining the spatial distribution of PA at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0a97e982d87e8fedcab23799495c9e
https://hal.archives-ouvertes.fr/hal-03362680
https://hal.archives-ouvertes.fr/hal-03362680
Autor:
Tom Houben, Sophie Reibel, Michael Reber, Valentina Pallottini, Eugeniu Vasile, Frank W. Pfrieger, Amélie Barthelemy, Martine Perraut, Izabela-Cristina Stancu, Valérie Demais
Niemann-Pick type C (NPC) disease is a rare and fatal lysosomal storage disorder presenting severe neurovisceral symptoms. Disease-causing mutations in genes encoding either NPC1 or NPC2 protein provoke accumulation of cholesterol and other lipids in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7d5482f09b8c017cf999a8dd6a96f88
https://doi.org/10.1101/2021.04.08.438990
https://doi.org/10.1101/2021.04.08.438990
Autor:
François Boudet-Devaud, Vincent Béringue, Anne-Marie Haeberlé, Yannick Bailly, Catherine Vidal, Valérie Demais, Aurélie Guillemain, Stanislas Demuth, Nancy J. Grant, Juliette Ezpeleta, Odile Kellermann, Benoit Schneider, Audrey Ragagnin
Publikováno v:
Brain Pathology. 28:240-263
In prion diseases, the brain lesion profile is influenced by the prion "strain" properties, the invasion route to the brain, and still unknown host cell-specific parameters. To gain insight into those endogenous factors, we analyzed the histopatholog
Autor:
Anne-Marie Haeberlé, Nicolas Vitale, Nancy J. Grant, Aurélie Guillemain, Yannick Bailly, Valérie Demais, Siaka Dole, Audrey Ragagnin, Anne-Sophie Wilding, Catherine A. Royer, Stéphane Gasman, Qili Wang
Publikováno v:
Prions-Some Physiological and Pathophysiological Aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6052845610f6ae49d537393fa42c3dc1
http://www.intechopen.com/articles/show/title/prion-proteins-and-neuronal-death-in-the-cerebellum
http://www.intechopen.com/articles/show/title/prion-proteins-and-neuronal-death-in-the-cerebellum
Autor:
Martine Perraut, Valérie Demais, Céline Keime, Amélie Barthélémy, Frank W. Pfrieger, Nicole Ungerer, Sophie Reibel
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2016, 36 (30), ⟨10.1523/JNEUROSCI.0900-16.2016⟩
Journal of Neuroscience, Society for Neuroscience, 2016, 36 (30), ⟨10.1523/JNEUROSCI.0900-16.2016⟩
Aging and pathologic conditions cause intracellular aggregation of macromolecules and the dysfunction and degeneration of neurons, but the mechanisms are largely unknown. Prime examples are lysosomal storage disorders such as Niemann-Pick type C (NPC