Use of Gene Expression Profiles of Peripheral Blood Lymphocytes to Distinguish BRCA1 Mutation Carriers in High Risk Breast Cancer Families

Autor: Marie-Laure Vuillaume, Nancy Uhrhammer, Véronique Vidal, Valérie Sylvain Vidal, Valérie Chabaud, Beline Jesson, Fabrice Kwiatkowski, Yves-Jean Bignon

Publikováno v: Cancer Informatics, Vol 7, Pp 41-56 (2009)

Mutations in two major genes, BRCA1 and BRCA2, account for up to 30% of families with hereditary breast cancer. Unfortunately, in most families there is little to indicate which gene should be targeted first for mutation screening, which is labor int

Externí odkaz: https://doaj.org/article/3ac49b0a27af4df88478ffb88582fd06

The doubling potential of T lymphocytes allows clinical-grade production of a bank of genetically modified monoclonal T-cell populations

Autor: Henri Vié, Régine Vivien, Philippe Lemarre, Valérie Chabaud, Soraya Saiagh, Béline Jesson, Patrice Chevallier, Thierry Guillaume, Ulrich Jarry, Catherine Godon, Béatrice Clémenceau

Publikováno v: Cytotherapy
Cytotherapy, Elsevier, 2018, 20 (3), pp.436-452. ⟨10.1016/j.jcyt.2017.12.002⟩
Cytotherapy, Elsevier, 2018, 20 (3), pp.436-452. 〈10.1016/j.jcyt.2017.12.002〉
Cytotherapy, 2018, 20 (3), pp.436-452. ⟨10.1016/j.jcyt.2017.12.002⟩

International audience; Background aims. To produce an anti-leukemic effect after hematopoietic stem cell transplantation we have long considered the theoretical possibility of using banks of HLA-DP specific T-cell clones transduced with a suicide ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd546f9b93247e1ad58cf916a6143eb
https://doi.org/10.1016/j.jcyt.2017.12.002