Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Valérie, Schreiber"'
Autor:
Shyamala Thirunavukkarasu, Mushtaq Ahmed, Bruce A. Rosa, Mark Boothby, Sung Hoon Cho, Javier Rangel-Moreno, Stanley K. Mbandi, Valérie Schreiber, Ananya Gupta, Joaquin Zuniga, Makedonka Mitreva, Deepak Kaushal, Thomas J. Scriba, Shabaana A. Khader
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
The ADP ribosyltransferases (PARPs 1–17) regulate diverse cellular processes, including DNA damage repair. PARPs are classified on the basis of their ability to catalyze poly-ADP-ribosylation (PARylation) or mono-ADP-ribosylation (MARylation). Alth
Externí odkaz:
https://doaj.org/article/4c22a3c3f8194eee8454f8a9197e2d78
Autor:
Valérie Schreiber, Reuben Mercier, Sara Jiménez, Tao Ye, Emmanuel García-Sánchez, Annabelle Klein, Aline Meunier, Sabitri Ghimire, Catherine Birck, Bernard Jost, Kristian Honnens de Lichtenberg, Christian Honoré, Palle Serup, Gérard Gradwohl
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101313- (2021)
Objective: Mice lacking the bHLH transcription factor (TF) Neurog3 do not form pancreatic islet cells, including insulin-secreting beta cells, the absence of which leads to diabetes. In humans, homozygous mutations of NEUROG3 manifest with neonatal o
Externí odkaz:
https://doaj.org/article/0eee5b4bdcfb4b04ae1c515cc6791a74
Autor:
Julie Piccand, Constance Vagne, Florence Blot, Aline Meunier, Anthony Beucher, Perrine Strasser, Mari L. Lund, Sabitri Ghimire, Laure Nivlet, Céline Lapp, Natalia Petersen, Maja S. Engelstoft, Christelle Thibault-Carpentier, Céline Keime, Sara Jimenez Correa, Valérie Schreiber, Nacho Molina, Thue W. Schwartz, Adèle De Arcangelis, Gérard Gradwohl
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 24-39 (2019)
Objective: Enteroendocrine cells (EECs) of the gastro-intestinal tract sense gut luminal factors and release peptide hormones or serotonin (5-HT) to coordinate energy uptake and storage. Our goal is to decipher the gene regulatory networks controllin
Externí odkaz:
https://doaj.org/article/ae5bc94129d345d5a7f7ab5313070cd2
Modulation of gene expression during differentiation by transcription factors promotes cell diversity. Despite their role in cell fate decisions, no experimental assays estimate their regulatory activity in a high-throughput manner and at the single-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bb7e9b966a3566237ae2e37c749290
https://doi.org/10.1101/2022.04.01.486696
https://doi.org/10.1101/2022.04.01.486696
Autor:
Valérie Schreiber, Vincent Heyer, Carole Beck, Najat Hanini, Bernardo Reina San Martin, Laurent Gauthier, Mikael Elofsson, Françoise Dantzer, Agnès Tissier, José Manuel Rodríguez-Vargas, Christian Boehler, Isabelle Robert
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, 2019, 26 (9), pp.1615-1630. ⟨10.1038/s41418-018-0233-1⟩
Cell Death and Differentiation, Nature Publishing Group, 2019, 26 (9), pp.1615-1630. ⟨10.1038/s41418-018-0233-1⟩
Cell Death Differ
Cell Death and Differentiation, 2019, 26 (9), pp.1615-1630. ⟨10.1038/s41418-018-0233-1⟩
Cell Death and Differentiation, Nature Publishing Group, 2019, 26 (9), pp.1615-1630. ⟨10.1038/s41418-018-0233-1⟩
Cell Death Differ
PARP3 has been shown to be a key driver of TGFβ-induced epithelial-to-mesenchymal transition (EMT) and stemness in breast cancer cells, emerging as an attractive therapeutic target. Nevertheless, the therapeutic value of PARP3 inhibition has not yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee6a36c26f906c5471f2e71cd75ad92
https://hal.science/hal-02330194
https://hal.science/hal-02330194
Autor:
Thue W. Schwartz, Julie Piccand, Adèle De Arcangelis, Nacho Molina, Mari L. Lund, Anthony Beucher, Sabitri Ghimire, Florence Blot, Valérie Schreiber, Sara Jimenez Correa, Christelle Thibault-Carpentier, Maja S. Engelstoft, Aline Meunier, Céline Lapp, Constance Vagne, Gérard Gradwohl, Perrine Strasser, Céline Keime, Laure Nivlet, Natalia Petersen
Publikováno v:
Piccand, J, Vagne, C, Blot, F, Meunier, A, Beucher, A, Strasser, P, Lund, M L, Ghimire, S, Nivlet, L, Lapp, C, Petersen, N, Engelstoft, M S, Thibault-Carpentier, C, Keime, C, Correa, S J, Schreiber, V, Molina, N, Schwartz, T W, De Arcangelis, A & Gradwohl, G 2019, ' Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production ', Molecular Metabolism, vol. 29, pp. 24-39 . https://doi.org/10.1016/j.molmet.2019.08.007
Molecular Metabolism
Molecular metabolism
Molecular metabolism, Elsevier, 2019, 29, pp.24-39. ⟨10.1016/j.molmet.2019.08.007⟩
Molecular Metabolism, Vol 29, Iss, Pp 24-39 (2019)
Molecular Metabolism
Molecular metabolism
Molecular metabolism, Elsevier, 2019, 29, pp.24-39. ⟨10.1016/j.molmet.2019.08.007⟩
Molecular Metabolism, Vol 29, Iss, Pp 24-39 (2019)
Objective Enteroendocrine cells (EECs) of the gastro-intestinal tract sense gut luminal factors and release peptide hormones or serotonin (5-HT) to coordinate energy uptake and storage. Our goal is to decipher the gene regulatory networks controlling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e444c342773de6de0b4168342183cc0
https://curis.ku.dk/portal/da/publications/rfx6-promotes-the-differentiation-of-peptidesecreting-enteroendocrine-cells-while-repressing-genetic-programs-controlling-serotonin-production(90f1beda-b090-460a-a08a-d4c307dbc5be).html
https://curis.ku.dk/portal/da/publications/rfx6-promotes-the-differentiation-of-peptidesecreting-enteroendocrine-cells-while-repressing-genetic-programs-controlling-serotonin-production(90f1beda-b090-460a-a08a-d4c307dbc5be).html
Autor:
Valérie Schreiber, Maria Hofstaetter, Michael O. Hottiger, Giody Bartolomei, Bianca Bertulat, Annette Becker, Daniela Meilinger, Heinrich Leonhardt, Peng Zhang, M. Cristina Cardoso, Lena Allmann, Daniel Eck
Publikováno v:
Journal of Biological Chemistry. 291:4873-4881
The epigenetic information encoded in the genomic DNA methylation pattern is translated by methylcytosine binding proteins like MeCP2 into chromatin topology and structure and gene activity states. We have shown previously that the MeCP2 level increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e45962e61d4457a65e23c93389c270f
https://doi.org/10.1074/jbc.m115.698357
https://doi.org/10.1074/jbc.m115.698357
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1608
The purification of poly(ADP-ribose) polymerase-3 (PARP-3) from overexpressing cells (Sf9 insect cells, Escherichia coli) has been updated to a fast and reproducible two chromatographic steps protocol. After cell lysis, PARP-3 protein from the crude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19e6d193dc317902c2832674777885d4
https://pubmed.ncbi.nlm.nih.gov/28695522
https://pubmed.ncbi.nlm.nih.gov/28695522
Publikováno v:
Methods in Molecular Biology
Methods in Molecular Biology, 1608, pp.373-394, 2017, ⟨10.1007/978-1-4939-6993-7_24⟩
Methods in Molecular Biology ISBN: 9781493969920
Methods in Molecular Biology, 1608, pp.373-394, 2017, ⟨10.1007/978-1-4939-6993-7_24⟩
Methods in Molecular Biology ISBN: 9781493969920
International audience; The purification of poly(ADP-ribose) polymerase-3 (PARP-3) from overexpressing cells (Sf9 insect cells, Escherichia coli) has been updated to a fast and reproducible two chromatographic steps protocol. After cell lysis, PARP-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0124c2d8e13fcd5fb85773b14c0934cf
https://hal.archives-ouvertes.fr/hal-02330264
https://hal.archives-ouvertes.fr/hal-02330264
Cell response to genotoxic stress requires a complex network of sensors and effectors from numerous signaling and repair pathways, among them the nuclear poly(ADP-ribose) polymerase 1 (PARP1) plays a central role. PARP1 is catalytically activated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d595d16a374d086f849be4ef1902aef
https://linkinghub.elsevier.com/retrieve/pii/S1084952116302981
https://linkinghub.elsevier.com/retrieve/pii/S1084952116302981