Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Valérie, Pasteau"'
Autor:
Alain P. Gobert, Gaelle Rollin-Jego, Tanguy Fortin, Fany Panayi, Rodolphe Billiras, Chloé Bardet, Valérie Pasteau, Arnaud François, Karine Albinet, Fabrice Iop, Caroline Louis
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
Molecular Pharmacology. 79:91-105
Although dopamine (DA) regulates the serine/threonine kinase Akt and its downstream substrate glycogen synthase kinase-3β (GSK-3β), the direct influence of dopaminergic receptors remains poorly characterized. Short-term incubation of Chinese hamste
Autor:
Millan Mark, Roberto Maggio, Valérie Audinot, Adrian Newman-Tancredi, Jean A. Boutin, Valérie Pasteau, Didier Cussac, Thierry Dubuffet, Francesca Novi, Gilbert Lavielle, Clotilde Mannoury la Cour
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 324:587-599
The novel, potential antipsychotic, S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide), displayed approximately 25-fold higher affinity at human (h) dopamine D(3) versus hD(2L) (long is
Publikováno v:
European Journal of Pharmacology. 485:111-117
Herein, we examined the direct coupling of human dopamine D1 receptors to G(s) proteins using an antibody capture assay together with a detection technique employing scintillation proximity assay beads. Using a specific antibody, dopamine (DA) and th
Autor:
Valérie Pasteau, Alain Gobert, Anne Dekeyne, Françoise Lejeune, Millan Mark, Adrian Newman-Tancredi, Didier Cussac, Jean-Michel Rivet
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 306:954-964
Agomelatine (S20098) displayed p K i values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. It also interacted with h5-HT2B receptors (6.6), whereas it showed low affinity at native (rat)/
Publikováno v:
Molecular pharmacology. 79(1)
Although dopamine (DA) regulates the serine/threonine kinase Akt and its downstream substrate glycogen synthase kinase-3β (GSK-3β), the direct influence of dopaminergic receptors remains poorly characterized. Short-term incubation of Chinese hamste
Autor:
Mark J, Millan, Clotilde, Mannoury la Cour, Francesca, Novi, Roberto, Maggio, Valérie, Audinot, Adrian, Newman-Tancredi, Didier, Cussac, Valérie, Pasteau, Jean-A, Boutin, Thierry, Dubuffet, Gilbert, Lavielle
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 324(2)
The novel, potential antipsychotic, S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide), displayed approximately 25-fold higher affinity at human (h) dopamine D(3) versus hD(2L) (long is
Publikováno v:
Neuropharmacology. 52(3)
Cloned, human dopamine D(1) receptors recruit multiple effectors but the G-protein subtype(s) activated by cerebral populations remain poorly defined, a question addressed using a rapid immunocapture technique. In rat striatum, dopamine (DA) and four
Autor:
Mauricette Brocco, Jean-Michel Rivet, C. Chaput, Adrian Newman-Tancredi, Manuelle Touzard, Didier Cussac, Millan Mark, Valérie Pasteau
Publikováno v:
Brain research. 920(1-2)
Unilateral 6-hydroxydopamine (6-OHDA) lesions of substantia nigra pars compacta (SNPC) neurons in rats induce behavioural hypersensitivity to dopaminergic agonists. However, the role of specific dopamine receptors is unclear, and potential alteration
Publikováno v:
Molecular pharmacology. 56(5)
The mitogen-activated protein kinase (MAPK) cascade is stimulated by both receptor tyrosine kinases and G protein-coupled receptors. We show that recombinant human dopamine D(3) receptors expressed in Chinese hamster ovary cells transiently activate