Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Valérie, Leblanc"'
Autor:
François Fabi, Kathy Grenier, Sophie Parent, Pascal Adam, Laurence Tardif, Valérie Leblanc, Eric Asselin
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177387 (2017)
Infertility is constantly increasing in Canada, where 16% of Canadian couples are experiencing difficulty conceiving. It is thought that infertility can emanate from the dysregulated communication between the embryo and the maternal endometrium. In o
Externí odkaz:
https://doaj.org/article/090871a051ce432e99ca42a0e5ac3ba2
Publikováno v:
Psycause : revue scientifique étudiante de l'École de psychologie de l'Université Laval. 8:8-10
La méditation pour promouvoir la santé psychologique suscite de l’intérêt et il y a lieu d’examiner si l’impact varie selon l’objet de l’attention. Cette étude compare les effets des méditations sur le souffle (MS) et de compassion (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::560fc3c373d2d5a553e4f7ad24503d6f
https://doi.org/10.51656/psycause.v8i2.20123
https://doi.org/10.51656/psycause.v8i2.20123
Publikováno v:
Medicinal Chemistry. 11:717-724
The search for new specific chemotherapeutic drugs designed to minimize the toxic side effects resulting from chemotherapy is still a subject of intense research. The objective of the current study was to design a non-steroidal-platinum(II) derivativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9339855481ab1cd5df80abdb546c3a6
https://doi.org/10.2174/1573406411666150504123750
https://doi.org/10.2174/1573406411666150504123750
Publikováno v:
European Journal of Medicinal Chemistry. 64:442-447
The synthesis of 7α-testosterone–chlorambucil hybrid is reported. This compound is made from testosterone in a 6 step reaction sequence and with 23% overall yield. An alternative convergent reaction sequence yielded the same hybrid through a Grubb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f15e77c36c2b900ebf27e434579f360
https://doi.org/10.1016/j.ejmech.2013.04.027
https://doi.org/10.1016/j.ejmech.2013.04.027
Autor:
Eric Asselin, François Fabi, Sophie Parent, Laurence Tardif, Kathy Grenier, Pascal Adam, Valérie Leblanc
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 5, p e0177387 (2017)
PLoS ONE, Vol 12, Iss 5, p e0177387 (2017)
Infertility is constantly increasing in Canada, where 16% of Canadian couples are experiencing difficulty conceiving. It is thought that infertility can emanate from the dysregulated communication between the embryo and the maternal endometrium. In o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379419dff76abdcf95a90b0f772dfc80
https://pubmed.ncbi.nlm.nih.gov/28475617
https://pubmed.ncbi.nlm.nih.gov/28475617
Autor:
Eric Asselin, Kevin Brasseur, Pijus Saha, Sophie Parent, Caroline Descôteaux, Valérie Leblanc, Gervais Bérubé, Sébastien Fortin
Publikováno v:
European Journal of Medicinal Chemistry. 48:385-390
In the course of efforts to develop 17β-estradiol-linked to anticancer agents targeting estrogen-dependent tissue, we identified three estradiol-linked platinum(II) complex analogs to cisplatin (E-CDDP) derivatives namely: VP-128 (1), CD-38 (2) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bb34006db999bd0dff5343206100fb
https://doi.org/10.1016/j.ejmech.2011.12.017
https://doi.org/10.1016/j.ejmech.2011.12.017
Autor:
Anne-Marie Fortier, Parvesh Chaudhry, Eric Asselin, Valérie Leblanc, Sophie Parent, Marie-Claude Dery
Publikováno v:
Biology of Reproduction. 85:1133-1142
Traditionally, oxytocin (OT) is well known to play a crucial role in the regulation of cyclic changes in the uterus, implantation of the embryo, and parturition. Recently, an additional role for OT has been identified in several types of cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eb8227f8544c9dd44846290e6508bce
https://doi.org/10.1095/biolreprod.111.093278
https://doi.org/10.1095/biolreprod.111.093278
Autor:
Sophie Parent, Eric Asselin, Kevin Brasseur, Gervais Bérubé, Caroline Descôteaux, Valérie Leblanc
Publikováno v:
Amino Acids. 43:923-935
Amino acids were transformed and coupled to chlorambucil, a well-known chemotherapeutic agent, in an attempt to create new anticancer drugs with selectivity for breast cancer cells. Among the amino acids available, tyrosine was selected to act as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9927be49f6414af4d291c1f6f1c4d8
https://doi.org/10.1007/s00726-011-1152-3
https://doi.org/10.1007/s00726-011-1152-3
Publikováno v:
Biology of Reproduction. 84:1045-1052
Resveratrol (trans-3,4N-trihydroxystilbene), a phytoalexin present in grapes and red wine is emerging as a natural compound with anticancer properties. However, the physiological and molecular effects of resveratrol on normal uterine cells are poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e0d113cd4db0fc0690292faa171468c
https://doi.org/10.1095/biolreprod.110.090076
https://doi.org/10.1095/biolreprod.110.090076
Autor:
Eric Asselin, Caroline Descôteaux, Valérie Leblanc, Kevin Brasseur, Atul Gupta, Gervais Bérubé
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:7388-7392
A series of D- and L-tyrosine-chlorambucil analogs was synthesized as anticancer drugs for chemotherapy of breast cancer. The novel compounds were synthesized in good yields through efficient modifications of D- and L-tyrosine. The newly synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bad4fbc7a7760306d787c92deb8b20f
https://doi.org/10.1016/j.bmcl.2010.10.039
https://doi.org/10.1016/j.bmcl.2010.10.039