Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Valérie, Jolivel"'
Autor:
Fabien Binamé, Lucas D Pham‐Van, Caroline Spenlé, Valérie Jolivel, Dafni Birmpili, Lionel A Meyer, Laurent Jacob, Laurence Meyer, Ayikoé G Mensah‐Nyagan, Chrystelle Po, Michaël Van der Heyden, Guy Roussel, Dominique Bagnard
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 11, Pp 1-16 (2019)
Abstract Current treatments in multiple sclerosis (MS) are modulating the inflammatory component of the disease, but no drugs are currently available to repair lesions. Our study identifies in MS patients the overexpression of Plexin‐A1, the signal
Externí odkaz:
https://doaj.org/article/9c93a265f0e349ccb476894277fab549
Autor:
Nicolas Collongues, Guillaume Becker, Valérie Jolivel, Estelle Ayme-Dietrich, Jérôme de Seze, Fabien Binamé, Christine Patte-Mensah, Laurent Monassier, Ayikoé Guy Mensah-Nyagan
Publikováno v:
Neurology and Therapy. 11:981-1042
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) resulting in demyelination and neurodegeneration. The therapeutic strategy is now largely based on reducing inflammation with immunosuppressive drugs. Unfor
Autor:
Valérie Jolivel, Susana Brun, Fabien Binamé, Jérémie Benyounes, Omar Taleb, Dominique Bagnard, Jérôme De Sèze, Christine Patte-Mensah, Ayikoe-Guy Mensah-Nyagan
Publikováno v:
Cells, Vol 10, Iss 3, p 698 (2021)
Microglial cells are key players in neural pathogenesis and microglial function regulation appears to be pivotal in controlling neuroinflammatory/neurological diseases. Here, we investigated the effects and mechanism of action of neurosteroid allopre
Externí odkaz:
https://doaj.org/article/56041ace58d848b0b70fecb739a9e217
Autor:
Thomas Pradeu, Paôline Laurent, Valérie Jolivel, Pauline Manicki, Lynn Chiu, Cécile Contin-Bordes, Marie-Elise Truchetet
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Though the immune system is generally defined as a system of defense, it is increasingly recognized that the immune system also plays a crucial role in tissue repair and its potential dysregulations. In this review, we explore how distinct immune cel
Externí odkaz:
https://doaj.org/article/96270cdf1c6c459ea7eb8e6b3100cd1c
Autor:
Edouard Forcade, Pierre Duffau, Estibaliz Lazaro, Emeline Levionnois, Carlo Chizzolini, Benoit Allard, Patrick Blanco, Julien Izotte, Joël Constans, Pauline Henrot, Pauline Manicki, Damien Leleu, Paôline Laurent, Thomas Pradeu, Valérie Jolivel, Alexis Groppi, Christophe Richez, Thierry Schaeverbeke, Julien Seneschal, Mohamed Jeljeli, Marie-Elise Truchetet, Frédéric Batteux, Cécile Contin-Bordes
Publikováno v:
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2021, pp.annrheumdis-2020-219748. ⟨10.1136/annrheumdis-2020-219748⟩
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2021, pp.annrheumdis-2020-219748. ⟨10.1136/annrheumdis-2020-219748⟩
ObjectiveInnate lymphoid cells-2 (ILC2) were shown to be involved in the development of lung or hepatic fibrosis. We sought to explore the functional and phenotypic heterogeneity of ILC2 in skin fibrosis within systemic sclerosis (SSc).MethodsBlood s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f351de10dc768e6672ce110189328a8
https://hal.archives-ouvertes.fr/hal-03386391
https://hal.archives-ouvertes.fr/hal-03386391
Autor:
Fédération Hospitalo-Universitaire Acronim, Joël Constans, Béatrice Demoures, Julien Seneschal, Cécile Contin-Bordes, Pierre Duffau, Marie-Elise Truchetet, C. Jacquemin, Jean-Luc Pellegrin, Jorge Eduardo Guimaraes, Valérie Jolivel, Christophe Richez, Anne Bertrand, Paôline Laurent, Marie-Sylvie Doutre, Estibaliz Lazaro, Isabelle Douchet, Thierry Schaeverbeke, Patrick Blanco, Liliane Khoryati
Publikováno v:
Arthritis & Rheumatology. 68:2784-2794
OBJECTIVE To investigate the relationship between vascular damage and fibrosis in systemic sclerosis (SSc) by testing the hypothesis that platelets contribute to skin fibrosis via the activation of human dermal microvascular endothelial cells (HDMECs
Autor:
Valérie Jolivel, Florian C. Kurschus, Ari Waisman, Morad Zayoud, Hayrettin Tumani, Felix Luessi, Stefan H.P. Kraus, Sinah Engel, Karolina Rosenfeld, Roberto Furlan
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
Neurology Neuroimmunology & Neuroinflammation
Neurology Neuroimmunology & Neuroinflammation, 2021, 8 (1), pp.e908. ⟨10.1212/NXI.0000000000000908⟩
article-version (Version of Record) 3
Neurology Neuroimmunology & Neuroinflammation
Neurology Neuroimmunology & Neuroinflammation, 2021, 8 (1), pp.e908. ⟨10.1212/NXI.0000000000000908⟩
ObjectiveTo assess the impact of laquinimod treatment on monocytes and to investigate the underlying immunomodulatory mechanisms in MS.MethodsIn this cross-sectional study, we performed in vivo and in vitro analyses of cluster of differentiation (CD1
Autor:
Verena Opitz, Julia Bruttger, Mirko H. H. Schmidt, Stefanie Keller, Betty Jurek, Tobias Bäuerle, Fabien Binamé, René Gollan, Frank Bicker, Michael K. E. Schäfer, Frauke Zipp, Jérôme Birkenstock, Valérie Jolivel, Robert Ploen, Laura Poisa-Beiro, Serge C. Thal, Ari Waisman
Publikováno v:
Acta Neuropathologica. 129:279-295
The contribution of microglia to ischemic cortical stroke is of particular therapeutic interest because of the impact on the survival of brain tissue in the ischemic penumbra, a region that is potentially salvable upon a brain infarct. Whether or not
Autor:
Felix Luessi, Valérie Jolivel, Steffen Lerch, Bettina Trinschek, Mario Hubo, Helmut Jonuleit, Laura Poisa-Beiro, Stefan H.P. Kraus, Magdalena Paterka, Frauke Zipp
Publikováno v:
International Immunopharmacology. 18:347-357
Cladribine is a purine nucleoside analog developed to treat lymphoid malignancies. Reported therapeutic benefits for the autoimmune disease multiple sclerosis indicate additional immunomodulatory effects beyond the well-characterized cytotoxic activi
Autor:
Valérie Jolivel, Raphaël Dumeunier, Anthony Romieu, David Vaudry, Pierre-Yves Renard, Yves Meyer, Jean-Alexandre Richard, Hubert Vaudry, Marc Massonneau
Publikováno v:
Bioconjugate Chemistry. 19:1707-1718
The self-immolative spacer para-aminobenzyl alcohol (PABA) was used as a key component in the design of new protease-sensitive fluorogenic probes whose parent phenol-based fluorophore is released through an enzyme-initiated domino reaction. First, th