Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Valérie, Janelle"'
Autor:
Shirin Lak, Valérie Janelle, Anissa Djedid, Gabrielle Boudreau, Ann Brasey, Véronique Lisi, Ali Smaani, Cédric Carli, Lambert Busque, Vincent-Philippe Lavallée, Jean-Sébastien Delisle
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 230-245 (2022)
Antigen-specific T cell expansion ex vivo followed by adoptive transfer enables targeting of a multitude of microbial and cancer antigens. However, clinical-scale T cell expansion from rare precursors requires repeated stimulation, which may lead to
Externí odkaz:
https://doaj.org/article/69663426dd644361ad6f2f2b985cbce2
Autor:
Valérie Janelle, Mathieu Neault, Marie-Ève Lebel, Dave Maurice De Sousa, Salix Boulet, Ludovic Durrieu, Cédric Carli, Chloé Muzac, Sébastien Lemieux, Nathalie Labrecque, Heather J. Melichar, Frédérick A. Mallette, Jean-Sébastien Delisle
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T-cell dysfunction arising upon repeated antigen exposure prevents effective immunity and immunotherapy. Using various clinically and physiologically relevant systems, we show that a prominent feature of PD-1-expressing exhausted T cells is the devel
Externí odkaz:
https://doaj.org/article/1007f9fb6e534841863c22c013ae6191
Autor:
Valérie Janelle, Mathieu Neault, Marie-Eve Lebel, Dave De Sousa, Salix Boulet, Ludovic Durrieu, Cedric Carli, Sebastien Lemieux, Nathalie Labrecque, Heather Melichar, Frederick Mallette, Jean-Sebastien Delisle
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/52c78fe87ac64d1399810f892f4f2e4e
T-Cell Immunotherapies Targeting Histocompatibility and Tumor Antigens in Hematological Malignancies
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Over the last decades, T-cell immunotherapy has revealed itself as a powerful, and often curative, strategy to treat blood cancers. In hematopoietic cell transplantation, most of the so-called graft-vs.-leukemia (GVL) effect hinges on the recognition
Externí odkaz:
https://doaj.org/article/865fd5cc57f6411691184099e1feafe9
Autor:
Jean-Sébastien Delisle, Jonathan L. Bramson, Ksenia Bezverbnaya, Mathieu Goupil, Myriam Khalili, Caroline Lamarche, Manon Richaud, Cédric Carli, Valérie Janelle, Amina Dahmani
Additional Tcm markers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140bad7026bcc0e5a92afa47a70a3e2b
https://doi.org/10.1158/2326-6066.22543915
https://doi.org/10.1158/2326-6066.22543915
Autor:
Jean-Sébastien Delisle, Jonathan L. Bramson, Ksenia Bezverbnaya, Mathieu Goupil, Myriam Khalili, Caroline Lamarche, Manon Richaud, Cédric Carli, Valérie Janelle, Amina Dahmani
The adoptive transfer of ex vivo–expanded T cells is a promising approach to treat several malignancies. Several lines of evidence support that the infusion of T cells with early memory features, capable of expanding and persisting after transfer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020c6aff842ba1937dd84cb6221f624e
https://doi.org/10.1158/2326-6066.c.6550456.v1
https://doi.org/10.1158/2326-6066.c.6550456.v1
Autor:
Alain Lamarre, Laurent Poliquin, Pascal Lapierre, Esther Tarrab, Marie-Pierre Langlois, Valérie Janelle
PDF file - 24K, Supplementary Figure 1. Complement system inhibition by CVF.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7806f2acc5a92f390b07aec1301741
https://doi.org/10.1158/2326-6066.22536092.v1
https://doi.org/10.1158/2326-6066.22536092.v1
Autor:
Alain Lamarre, Laurent Poliquin, Pascal Lapierre, Esther Tarrab, Marie-Pierre Langlois, Valérie Janelle
PDF file - 135K, Supplementary Figure 3. Effectiveness of NK cell depletion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ea46898a8fa071475af49cd0d84e16
https://doi.org/10.1158/2326-6066.22536086.v1
https://doi.org/10.1158/2326-6066.22536086.v1
Autor:
Alain Lamarre, Laurent Poliquin, Pascal Lapierre, Esther Tarrab, Marie-Pierre Langlois, Valérie Janelle
PDF file - 26K, Supplemental Figure 2. MDSC proportions following CVF treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b25cb9bc459c543519c9b8e2640691
https://doi.org/10.1158/2326-6066.22536089
https://doi.org/10.1158/2326-6066.22536089
Autor:
Alain Lamarre, Laurent Poliquin, Pascal Lapierre, Esther Tarrab, Marie-Pierre Langlois, Valérie Janelle
Although the role of the complement system in cancer development has been studied, its involvement in the development of an antitumoral immune response remains poorly understood. Using cobra venom factor (CVF) to inhibit the complement cascade via C3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d31b402a7724bd79cbbfe4213abb6f
https://doi.org/10.1158/2326-6066.c.6548045.v1
https://doi.org/10.1158/2326-6066.c.6548045.v1